1. BH3 THF 2. H2O2, NaOH

Draw the major prodct from this reaction. Use a dash and/or wedge bond to indicate the stereochemistry of substituents on asymmetric centers, where applicable. Ignore acid byproduct. Incorrect, 1 attempt remaining 1. Br2, H₂O 2. NaOH 0

1. Consider two SN1 reactions: (A) water and tert-butylbromide and, (B) water and 2- bromopropane, both having the same concentration of reactants. a. Draw the reactants (nucleophile and substrate) for both reactions (A & B). b. Draw a curved arrow mechanism for the reaction between water and tert-butylbromide (A). Show all reactants, intermediates, and products do not show transition state structures. c. Draw products of each reaction (A & B). d. Predict which reaction will be faster (A or B). - e. Draw an energy vs. reaction coordinate diagram showing only the rate-determining step for both reactions on the same set of axes (axes available on the next page). Draw the reaction (A) with a dotted line and (B) with a solid line, and assume that the potential energies of the reactants are the same in both reactions (i.e. the only difference is in the energies of the two different transition states and resulting intermediates).

Please answer correct

Curved arrows are used to illustrate the flow of electrons . Using the provided starting and product structures, draw the curved electron - pushing arrows for the following reaction or mechanistic step(s) . Be sure to account for all bond - breaking and bond - making steps.

all one answer both

5. Our textbook gives two reactions that result in anti-Markovnikov additions with alkenes. i. ii. iii. The first is hydroboration forming an anti-Markovnikov Draw the single mechanistic step of the "syn" addition which determines the anti- Markovnikov addition. I The second, the radical addition of HBr to an alkene, has a critical propagation step which determines the addition selectivity. Draw this step below.

2. Determine an appropriate synthetic step that could be used to carry out the following transform in the forward direction. (one step) th-st

True/False : Two separate questions shown in picture.

1. Design a synthesis of the following epoxide from the indicated alkyne. Be sure to consider how to get the required geometry of the two methyls. H "Me Me H (+ enantiomer)