Why The Worm, C. Elegans

In this project, C. Elegans are hermaphrodite worms that will be used since they are easy to maintain in lab, as well as have short life cycles. The gene that the project attempted to knockdown in C. Elegans with RNAi treatment is the unc-22 gene. RNAi disrupts gene expression in the presence of double stranded RNA (dsRNA) that is complementary to target gene sequence. The unc-22 gene codes for a muscle protein called twitchin in wild-type worms. The Unc-22 is required for muscle regulation and maintenance in C.Elegans. To verify that the RNAi treatment worked, would check the unc-22 mRNA levels in the worms, in addition to phenotype observation.

Living organisms contain molecular and cellular machinery that maintain homeostasis. All of this machinery is governed by the laws of Physics and Chemistry and with our increased understanding of the biological sciences we understand the complex relationship of all three of these sciences in living systems. Each science is inherently dependent on another: Biology Chemistry Physics Mathematics.

Pascale et al. (2000), adds that as this experimentation and discovery is taking place, the components of the living systems self-organize; thus, creating new forms that emerge from the turmoil.

Please use your own words. Any direct quote would result in an automatic zero for the pertaining question.

Mark Twain Tons of writers use their pasts to influence their style of writing. Writers have used their past for centuries to write. Mark Twain is known as one of the greatest writers of his time. He uses his sense of humor and irony to captivate readers. Mark Twain’s books give us knowledge of the past and the events of his life.

Next year, I plan to major in Computer Engineering and begin a career helping make the world a better place through innovative technology. I realized my talents for math and sciences during freshman year of high school, and remember the exact moment I knew engineering was meant for me. While exploring the engineering shop at my vocational technical high school, the teacher showed my class a video of MIT students designing prosthetic limbs for amputees. It was then that I realized I could use my love of math and science to really help people.

When I was in 6th grade, my mother had to drag me by the ear to join the CTMS Science Team. At first, I hated every moment of it as I avoided the competitions by whining and crying. As time progressed, I would sit down every day with my neatly organized binder and stepped into a world of chemicals reactions. I soon realized that I wasn’t doing it because my parents were forcing me to; I was doing it because the science behind every ionic and covalent bond enthralled

In Year 8, a radiotherapist came into my school with a request - to help him develop a game to explain the process of radiotherapy to his patients. I decided to help out of curiosity, thinking that it would be interesting and that I'd learn something new. It was during the development process that I learnt my first lines of Python - which I now use extensively for my programs. That experience fueled my fascination with technology and its impact on the world around me, watching how the application of computing in other fields has bettered the lives of others.

Ironically, these interests stemmed from the least scientific place possible--my 4th grade reading test. While taking the test, I came across an article about AIDS, something I had heard about but never tried to understand. As it was an assessment, I was forced to read the intimidating article, only to find it extremely interesting! Immediately after, I wanted to find out more. However, these are not topics generally taught in elementary and middle schools, so I did a lot of self-studying, reading scientific journals--such as AAAS Science--and watching videos online. Then, as an eighth grader, I was given the opportunity to participate in a weeklong bioengineering summer camp at the University of Illinois, which was filled with exciting lectures and activities covering topics ranging from cell culture to imaging techniques; it covered so much that my naive eighth grade self could barely retain all that information. However, in particular, I vividly remember one specific lecture about quantum dots and how they could be the next big frontier of cancer research. Throughout the lecture, the more the professor elaborated on his studies of these nanocrystals, the more giddy I became with questions. How do quantum dots interact only with specific cells? Could quantum dots be used to monitor radiation levels in patients? When the professor finally took questions at the end of his talk, all my curiosities poured out, turning it

My mentor, professor Rob Phillips has always advocated for applying these principles to solve biological problems. I helped teach his class biology lab course Bi1x, as a TA and the curriculum emphasizes the principles derived from physics and mechanics in approaching biological questions. The modules reflect how we can through the use of quantitative analysis and our basic understanding of theories form hypotheses and models. For example, in our drosophila module, we quantify the bicoid gradient in the embryo and compare how its expression affects the placement of the cephalic furrow. Throughout the process, we compare the textbook French flag model and learn how to quantitatively measure the levels of bicoid and furrow in the embryo. In the module I developed, we engineered strains of C. elegans that would allow us to look at the network circuitry of neurons using optogenetics.

If you have noticed that the wood around one of your window frames has become soft to the touch, the wood around your window is rotting. Unfortunately, once the wood starts rotting, you can’t stop the process. However, you can patch the wood and allow yourself some time to save up to replace the frame.

The central idea of the passage is that worm like creatures live i total darkness and the story is about how they have adapted and how do they stay alive. On the ocean floor there is small vents coming from volcances and the creatures saty on the vent and that is how they stay alive because while beging on those vents there is heat transfered into there enrgey and food. and so that is mainly the whole passage is how they stay

In the course of AP Biology, there are four “Big Ideas”. The first one is “The process of evolution drives the diversity and unity of life”. The second is “Biological systems utilize free energy and molecular building blocks to grow, to reproduce and to maintain dynamic homeostasis”. The third is described as, “Living systems store, retrieve, transmit and respond to information essential to life processes.” And finally the four is “biological systems interact, and these systems and their interaction possess complex properties”. (College Board).

Staring at engine components of a car as well as holding a smartphone with almost unbelievable thickness fascinated me in many ways indirectly leaded me into getting to know more through different sources about machines ranging from transportation to communication devices. Two years of A-level preparation, further solidified my interest in this area as I found myself very fond of learning mathematics, physics and mechanics in particular. In addition, my curiosity in the operation and dynamics of objects naturally influences my choice of degree, leading me towards Engineering as it is a discipline which satisfy my own interest and most probably bring out the best of me.

I would spend hours together experimenting and analyzing various mechanics around me like the ball bearings in my bicycle & roller skates and would be fascinated by my spring loaded toy cars. During my higher secondary schooling, I showed special interest in mathematics and physical sciences and in order to supplement the education that I received in school, I became a habitual reader of science magazines and books. As a direct consequence of this, I came to know about the latest developments in the field of science and engineering, especially aerospace and manufacturing engineering as it deeply interested me and I was naturally inclined to like the subject. The basics I learnt in school only whetted my appetite for more learning. It was but natural I would choose to take up manufacturing engineering as a career choice when I joined