The Skeletal System Of Human Body

Exploring the Skeletal System The precise number of bones in the adult human skeleton varies from one person to another, but on average there are 206 bones varying shapes and sizes. The skeleton is divided into two main parts. The central bones of the skull, ribs, spin (vertebral column) and breast bone (sternum) form the axial skeleton. The bones of the arms and legs, along with the shoulder blade (scapula), collar bone (clavicle) and pelvis make up the appendicular skeleton.

Osteitis deformans or as we all know it as Paget’s disease, was first described in the year 1876 by an English surgeon named Sir James Paget. This disease results in enlarged or deformed bones due to excessive breakdown and formation of bone tissue (Reumatología Clínica). Since there is a disturbance in the bone remodeling stage, the bones may look enlarged but it is brittle, softer, and weaker which leads to fractures and deformities (MedicineNet). This disease is a chronic bone disorder, which means that it is long term and cannot be prevented or cured by medications. Also, this disease is mostly asymptomatic meaning it does not produce or show any symptoms, which is quite terrifying. It is mostly detected when patients get an x-ray for something else. This is most commonly located in the

Paget’s disease of the bone (PDB), also called Osteitis Deformans, is a chronic, slowly progressive skeletal condition of abnormally rapid bone destruction and reformation. PDB is the second most common bone remodeling disease after osteoporosis. The new bone is structurally abnormal, dense and fragile. The bones that are frequently affected are in the spine, skull, pelvis and lower legs. The disease does not spread bone to bone, it will stay constant in the affected bone or bones throughout the patient’s life. This condition can cause bone pain, arthritis, deformities and fractures. The osteoclast is the primary cell affected by PDB, this will show morphological and physiological abnormalities4. Osteoblasts are increased in

Most persons with Paget disease are asymptomatic. In these patients, the incidental finding of an elevated serum alkaline phosphatase level or characteristic radiographic abnormality may lead to detection of the disease. However, when symptoms do occur, bone pain is the most common

The skeletal system consists of bones, joints, and associated cartilages. These provide shape and support for the body and protect internal organs and structures. The marrow cavities within some bones serve as the site of hematopoiesis. The also skeleton serves as the reservoir of calcium and phosphorus. A common pathology of the skeletal system is rheumatoid arthritis (RA). It is a chronic systemic disease characterized by autoimmune inflammatory changes in the connective tissue throughout the body. • Celecoxib (Celebrex) is a type of non-steroidal anti-inflammatory drug (NSAID) that will directly target cyclooxygenase-2, COX-2, an enzyme responsible for inflammation and pain. Celecoxib is available in 50 mg, 100mg, 200 mg, and 400 mg capsules.

The etiology of paget’s disease of bone (PDB) is unknown, but I would consider the influence of hereditary and environmental factors in paget disease. A viral cause has been proposed based upon

Paget's disease of bone (PDB), also known as osteitis deformans, is named after Sir James Paget, an English surgeon, who first described the disease in 1877. Since then, research has determined that 15% to 40% of cases are inherited and the balance is thought to be caused by exposure to a “slow” viruses like human respiratory syncytial virus or canine distemper virus, however, symptoms may not appear for many years afterward. In about half of cases that are hereditary, a mutated gene has been isolated that is known to cause osteoclasts to become rogue and un-regulated. PDB causes long bones to grow unnaturally long causing pain and osteoarthritis, hearing loss and nervous systems disorders from pressure on the brain caused by cranium overgrowth,

Patients who have osteolytic lesions of Paget’s disease is suggested to have a repeat x-ray approximately 1 year after radiological diagnosis to determine whether there has been improvement with therapy or worsening in the absence of therapy. Subsequent x-rays may be considered in the event of persistent elevations of biochemical markers of bone turnover or the presence of bone pain and to determine when there is resolution of the lesion.

Clinical manifestations of osteoporosis include back pain caused by a fractured or a collapsed vertebra, Loss of patient height over time, stooped posture, and also bone fracture which occurs more easily than expected. Clinical manifestation for Paget’s disease depend on the affected part. Manifestations include hip pain, hearing loss or headache due to the overgrowth of skull bone, pain, numbness, and tingling in the arm or

The skeletal system is made up of 206 bones which protects, support and allows the human body to move. The skeletal system also consists of tissues such as; tendons, ligaments and cartilage - these components connect the bones together which results to the posture and framework of the body. The skeletal system of a new born baby consists of more bones than an adult (roughly 300 bones); this is because the bones have not been joined together by the tissues. As the human body grows, the smaller bones are joined together to form larger bones in the body. Teeth are also a part of the skeletal system - they are made of dentin and enamel. Enamel is the strongest substance in the body. The structure of the skeletal system on a whole consists of ligaments, tendons, cartilage, joints, sockets and bones which all interrelate and play a massive part in the functioning of the body by protecting the internal organs and allowing the body to maintain balance and posture.

The MS Kinect has evolved for gaming purposes initially but sooner it came out with many more possibilities higher than just gaming so Microsoft decided to launch a separate device (similar to Kinect for XBOX 360) called as Kinect for Windows , along with a SDK for the developers. One such possibility is human authentication system based on the anatomy of human skeletal structure which is more advance and reliable security system.

The skeletal system includes the osseous tissues of the body and the connective tissues that stabilize or interconnect the individual bones. The bone is a dynamic tissue. Throughout the lifespan, bone adjusts to the physiologic and mechanical demands placed on it by the processes of growth and remodeling.

Two hundred and six individual bones compose the adult human skeleton. In addition to providing structure and protection for our most vital organs, bones store minerals and aid in blood cell production. They are considered to be just as much a vital organ as the heart or liver. Under normal circumstances, throughout a person’s life as older bone is broken broken down it is immediately rebuilt and replaced but when there is an imbalance in this delicate cycle the bones integrity becomes compromised. Osteoporosis, meaning porous bone, is a disease that occurs when an individual loses too much bone mass, makes to little or a combination of both. This imbalance leaves the bones weak and brittle putting an individual at risk for break or

The Skeletal system is comprised of joints and bones as well as tendons, ligaments, and cartilage that connect them. Our skeletal system works together with the body to provide movement and protection for humans to live. However, skeletal disorders and diseases can threaten the system causing pain, inability to move, breakage, defects, and other harmful conditions. For instance, Paget’s disease is one that disturbs the normal process of bone growth. About one millions adults in the U.S. were reported to have this bone disease and many more may not even know it.

The human body is a complex network that has many organ systems designed for proper functioning. As the body ages over time, it also affects the effectiveness of these organ systems. One of the organ systems that demonstrated the most significant age-related changes have to be the musculoskeletal system. The musculoskeletal system provides the most obvious external signs of aging because its main function is to provide protection, support and movement of the muscles and bones (Aldwin). These functions are essential to the mobility and strength of the adult population in order to preserve their quality of life.