Introduction The question of antibiotic resistance is a growing phenomenon in contemporary society and modern medicine; it pertains to pathogenic organisms and is one of the most eminent issues of public health in the twenty-first century. Though resistant genes are ancient, its increasing prevalence poses a threat. It demands a greater need for antibiotic therapies. New resistance mechanisms may spread globally and limit our ability to treat disease and lead to a giant hole in the pillars of modern medicine. The immense increase in antibiotic resistance can be attributed to many factors. Along with spontaneous gene mutation, natural selection, and cell-to-cell gene transfer, humans play a huge part in the worsening of the epidemic. The Union of Concerned Scientists estimated in 2001 that more that seventy percent of the antibiotics used in the United States are given to food animals without disease to increase growth and decrease probability of mortality; medicine is used ensure and maximize profit. The misuse of antibiotics leads to an increase in resistance in that it exposes bacteria to antibiotics when this exposure is not necessary. Additionally, culturally-ingrained practices of using antibiotics sans prescription, sharing antibiotics with others, and over-prescription and dispensing antibiotics either incorrectly or needlessly due to the commercialization of medicine in combination with patients’ exaggeration of disease symptoms all contribute to the excessive use
Antibiotics are inarguably one of the greatest advances in medical science of the past century. Although the first natural antibiotic Penicillin was not discovered until 1928 by Scottish biologist Alexander Flemming, evidence exists that certain plant and mold growths were used to treat infections in ancient Egypt, ancient India, and classical Greece (Forrest, 1982). In our modern world with the advent of synthetic chemistry synthetic antibiotics like Erithromycin and its derivative Azithromycin have been developed. Antibiotics have many uses including the treatment of bacterial and protozoan infection, in surgical operations and prophylactically to prevent the development of an infection. Through these applications, antibiotics have saved countless lives across the world and radically altered the field of medicine. Though a wonderful and potentially lifesaving tool, antibiotic use is not without its disadvantages. Mankind has perhaps been too lax in regulation and too liberal in application of antibiotics and growing antibiotic resistance is the price we must now pay. A recent study showed that perhaps 70% of bacterial infections acquired during hospital visits in the United States are resistant to at least one class of antibiotic (Leeb, 2004). Bacteria are not helpless and their genetic capabilities have allowed them to take advantage of society’s overuse of antibiotics, allowing them to develop
Throughout my life, adults have insisted the use of antibiotics to fight against the most inconsequential illnesses, whether it’s the cold or the flu. However, neither illness is due to invasion of bacteria. This misuse can lead to antibiotic resistance, also known as antimicrobial resistance(AMR), currently one of the central issues facing the public health system. While the process for antibiotic resistance occurs naturally through the process of adaptation, the mismanagement of antibiotic resources has accelerated the rate at which the bacteria adapt. The occurrence of this misinformation isn’t limited to a few adults: even some of my peers suggest taking antibiotics when faced with the flu. This leads to asking whether AMR is truly a problem and are present regulations enough to combat the issue.
Antibiotic resistance can develop wherever antibiotics are: medical facilities, animal products and communities. Breaks in infection control, inadequate water sanitation and poor hygiene all contribute to the spread of resistant bacteria from person to person (Collignon, et al., 2015). The majority of antibiotic usage worldwide is in animals raised as a food source (Collignon, et al., 2015). 80% of antibiotic use in the United States is for growth promotion and disease prevention of farm animals used for food sources (CDC, 2015). This usage of antibiotics leads to the development of resistant bacteria, which spread to people via the food chain or water (Collignon, et al., 2015).
Since antibiotics, such as penicillin, became widely available in the 1940s, they have been called miracle drugs. They have been able to eliminate bacteria without significantly harming the other cells of the host. Now with each passing year, bacteria that are immune to antibiotics have become more and more common. This turn of events presents us with an alarming problem. Strains of bacteria that are resistant to all prescribed antibiotics are beginning to appear. As a result, diseases such as tuberculosis and penicillin-resistant gonorrhea are reemerging on a worldwide scale (1).
Antibiotic resistance has emerged as one of the greatest public health concerns of the 21st century. Nearly every type of bacteria has become stronger and less responsive to antibiotic treatment. This can eventually make it impossible to treat certain infections, leading to serious disability or death. The increasing prevalence of antibiotic-resistant bacterial infections can be attributed to overuse and over prescription. The uses of antibiotics in livestock are increasing resistance for animals and humans.
Antibiotic resistance is when microorganisms, such as bacteria, are able to survive an exposure to antibiotics and these bacteria are now resistant to the effects of these antibiotics. Antibiotic resistance in bacteria has been an issue since antibiotics were discovered. The fact that bacteria can become resistant to our medical treatments such as antibiotics is a natural evolutionary process, but there are certain human contributions that definitely speed up the process. For example, one of the main contributions that will be discussed is the problem of over prescription of the antibiotic drugs. The
Widespread use of antibiotics has been very controversial in the media as well in the general population. Due to these controversies, it is very misunderstood to how antibiotics work leading to many patients in the hospital setting wanting to take them when it is not necessary or refusing to take when it is necessary for their survival. Some of this controversy is due to antibiotic resistance, which has spread an alarming rate in the 21st century (Walsh, 2000). Antibiotic resistance is the result of very strong bacteria or microbes that are resistant to the antibiotic prescribed and those microbes accumulate overtime by their survival, reproduction and transfer, leading to increased levels of antibiotic resistance.
Also known as superbugs, these bugs are resistant to our modern day antibiotics. People around the world are trying to figure out alternatives to this plague. These bugs have evolved over years and years becoming stronger and passing down genes from generation to generation, To slowly become the super bugs that they are known as today. Often these resistant genes are caused by overuse of antibiotics by humans and farm animals, but this is not always true. Recently the ARS (the American Recorder Society) found antibiotic resistance in prairie soils that had no human contact. Antibiotic resistance is commonly viewed as a result of antibiotic overuse in humans and animals, Recently found antibiotic-resistant
In the past tense 60 years, antibiotic drugs have been critical to the fight against infectious disease caused by bacteria and other microbe. Antimicrobial chemotherapy has been a lead cause for the dramatic rise of norm life expectancy in the Twentieth Century. 1 However, disease-causing bug that have become resistant to antibiotic drug therapy are an increasing public health trouble. “Wound contagion, tuberculosis, pneumonia, gonorrhea, childhood ear infections, and septicemia are just a few of the diseases that have become hard to treat with antibiotics.” 2 One part of the job is that bacteria and other germ that cause infections are remarkably resilient and have developed several ways to resist antibiotics and other antimicrobial drug. 3 Another part of the problem is due to increasing use, and abuse, of existing
Supporting Data:Over the past century of antibiotic discovery and development, few parallel and independent lines of discovery have been fruitful. The development of strategies to prevent the evolution of resistance strains of microbes has been a top priority. In clinical practice, several measures that have been tested to reduce the incidence of resistance development, including
The development of antibiotics was an important advancement in 20th century medicine. Previously deadly infectious diseases are now routinely treated with antibiotics. Moreover, for modern-day medical procedures such as chemotherapy treatment to be successful, antibiotic use is necessary. For these reasons, the prospect of bacteria developing widespread resistance to antibiotics is a major concern as it would render many modern-day medical therapies unviable.
This research will investigate whether antibiotics, as an effective treatment for bacterial diseases, have become inadequate and ineffectual and, if so, conclude whether the world may be on the precipice of a post-antibiotic era by determining if antibiotic resistance is on the rise in the 21st century.
According the World Health Organization (WHO), antibiotic resistance is one of the world’s greatest health threats to date (Haddox, 2013). In the article, The Health Threat of Antibiotic Resistance, Gail Haddox (2013) discusses the danger antibiotic resistance poses in today’s society and strategies to prevent the expansion of antibiotic resistance. In Europe alone, an estimated 25,000 deaths have been attributed to multi-resistant infections (Haddox, 2013). Common infections are now harder to treat due to the increased resistance to antibiotics across the world, in fact some are becoming untreatable. Antibiotics should be treated like oil, a non-renewable resource (Haddox, 2013).
Antibiotic resistance does not evolve frequently. However, due to the rapid social development, more and more bizarre diseases are appearing around us. The diversity in the standards and perceptions of living has brought us bunch of consequences, including the illogical treatments toward illness and pharmaceutical production. Many people don’t know how to use drugs correctly or refuse to do so; some industry owners know how to properly manage their production lines but refuse to do that. Human’s
The overuse of antibiotics has been a problem for well over a decade. This misuse leads to many nonvisible problems arising within the human population. As the use of antibiotics increases, the number of antibiotic resistant bacteria also increases. When bacteria become resistant to an antibiotic, another antibiotic must be used to try and kill it and the cycle becomes vicious. Michael Martin, Sapna Thottathil, and Thomas Newman stated that antimicrobial resistance is, “an increasingly serious threat to global public health that requires action across all government sectors and society” (2409).