Introduction Antibiotics are amongst the most important medical discoveries and their introduction represents a remarkable success story (Hedin, 2011). The term antibiotics literally means against life (Walsh, 2000). Thus antibiotics can be used against any microbe such as bacteria, viruses, fungi, and protozoa. However, some people use the term to only apply to bacteria, but in this paper, the more appropriate term will be used.
Widespread use of antibiotics has been very controversial in the media as well in the general population. Due to these controversies, it is very misunderstood to how antibiotics work leading to many patients in the hospital setting wanting to take them when it is not necessary or refusing to take when it is necessary for their survival. Some of this controversy is due to antibiotic resistance, which has spread an alarming rate in the 21st century (Walsh, 2000). Antibiotic resistance is the result of very strong bacteria or microbes that are resistant to the antibiotic prescribed and those microbes accumulate overtime by their survival, reproduction and transfer, leading to increased levels of antibiotic resistance.
I have chosen this topic due to the controversies of using antibiotics due to antibiotic resistance.
…show more content…
There is a huge need for antibacterial drugs as infectious diseases are the second leading cause of death worldwide and the third leading cause of death in developed countries (Projan, 2003). Over the past 60-70 years, most antibiotics have been discovered by screening of soil samples for natural products that kill bacteria, including known pathogens, first on culture plates and then in animal infections (Walsh, 2000). There are three proven targets for the main antibacterial drugs, bacterial cell all biosynthesis, bacterial protein synthesis, and bacterial DNA replication and
According to previous, excessive use of antibiotics is one of the causes of drug resistance in different pathogens, this concern has caused many hospitals around the world develop guidelines and strategies to use appropriate antibiotics and are committed themselves to
Antibiotics have played an essential role in the fight against diseases and infections since the 1940’s. Antibiotics are a leading cause for the rise of global average life expectancy in the 20th and 21st century. They have greatly reduced illnesses and deaths due to diseases. With the introductions of antibiotics in the 1940’s, like penicillin into clinical practice, formally deadly illnesses became immediately curable and saved thousands of lives (Yim 2006). Antibiotic use has been beneficial and when prescribed and taken correctly their effects on patients are exceedingly valuable. However, because these drugs have been used so widely and for such a long period of time the bacteria that the antibiotics are designed to kill have adapted,
Antibiotic resistance is a phenomenon in which germs evolve to be able to resist the action of drugs. This causes illnesses that were once easily curable with antibiotics to become dangerous infections, requiring alternative medications or higher doses. With millions of deaths increasing every year, antibiotic resistance has become one of the world's most pressing public health problems. This essay will explain the key causes of the emergence of resistant bacteria, including antibiotic misuse, inappropriate prescribing and availability of few new antibiotics, and outline relevant effects of antibiotic resistance.
The misuse of antibiotics has the potential to set society back in time to the dark ages. It is time to end the careless use of these valuable antimicrobial that so many take for granted. Antibiotic resistance continues to expand and evolve and solutions to this epidemic need to implemented. By establishing stewardships, educational programs, and restrictions it teaches the severity of this issue and action that must be taken in order to decrease resistance. Antibiotic resistance is a multifactorial issue. Introducing preventative measures in hospitals will be most effective in reducing resistance, as well as eliminating the trend of misusing antibiotics.
The general populace of western civilization may believe that modern medicine is limitless and that numerous afflictions that are common can be easily resolved with the major strides medicine has taken in the past century. In the case of antibiotics, this couldn’t be farther from the truth and its use leaves a nasty prospect for the future. Antibiotics, the type of drug that is capable of killing harmful bacteria, is widely regarded as a simple gift from medical research and is expected to be prescribed for even the mildest of illnesses. However, the use of antibiotics has proved that it comes with a terrible byproduct: leftover bacteria that survives the drug and evolves strains that are resistant to the drugs the world currently
Modern day society is constantly in motion. The miracle drug, known as antibiotics, was a remarkable scientific advancement of the 1940’s era and seems to keep up with our demands. It has become the foundation of medicine and health care in today’s society.
“The Antibiotic Resistance Crisis” is an article on the National Center for Biotechology Information's website and consequently follows many of the conventions expected of an online article. Before the main body of text is even shown, the author's name is written and link to further information about the author is provided. This allows the reader to research what the author has published before and gain a better appreciation of their past work. The article itself is single-columned and divided into a a series of headings and subheadings that help organize and divide the text into smaller pieces. These pieces relate to the overall topic of how the overuse and misuse of antibiotics over the past century has led to the increasing ineffectiveness of antibiotics against various strains of bacteria. Because the article is published by a scientific organization, it is a fairly
Without a doubt, the issue with antibiotic resistance has become one of the most urgent health problems in the world. Recent studies have proven that antibiotics are becoming less effective in the recent years. For instance, developing countries like China and Kuwait experienced rapid growth in antibiotic resistance. In the years between 1994 and 2002 the reported cases of hospital and community-acquired antimicrobial infections for China boosted from 22% to 41% and Kuwait also experienced an average of 17% growth from 1999 to 2003 (Zhang 1). As the prevalence of superbugs is becoming more common due to excessive or incorrect use of penicillin and quinolones, people are more susceptible to contact this lethal microbe. The existence of antibiotic is meant to be beneficial to the human population because the drug itself is very effective at curing illnesses and enhancing food safety (Clemmitt 1). At the same time, people are generating a more serious issue by overusing the drugs.
The development of antibiotics was an important advancement in 20th century medicine. Previously deadly infectious diseases are now routinely treated with antibiotics. Moreover, for modern-day medical procedures such as chemotherapy treatment to be successful, antibiotic use is necessary. For these reasons, the prospect of bacteria developing widespread resistance to antibiotics is a major concern as it would render many modern-day medical therapies unviable.
This research will investigate whether antibiotics, as an effective treatment for bacterial diseases, have become inadequate and ineffectual and, if so, conclude whether the world may be on the precipice of a post-antibiotic era by determining if antibiotic resistance is on the rise in the 21st century.
Antibiotics have become a very important part of medicine. It is used to treat all kinds of bacteria, infections, diseases. Sadly, antibiotics have been coming to an end, they are being used more and more often everyday. They are being used so much that the bacteria they are being used to treat have been starting to become resistant to these antibiotics. Many infections that were once so easy to be treated have been gaining a stronger resistance. This is because of how the bacteria have a special enzyme that kills and eats up the antibiotics. As well as how the resistance that bacteria have can easily be passed off from one bacteria to another. This makes the resistance to antibiotics spread faster and increase rapidly. Much of the bacteria with resistance usually have it in their genes.
According the World Health Organization (WHO), antibiotic resistance is one of the world’s greatest health threats to date (Haddox, 2013). In the article, The Health Threat of Antibiotic Resistance, Gail Haddox (2013) discusses the danger antibiotic resistance poses in today’s society and strategies to prevent the expansion of antibiotic resistance. In Europe alone, an estimated 25,000 deaths have been attributed to multi-resistant infections (Haddox, 2013). Common infections are now harder to treat due to the increased resistance to antibiotics across the world, in fact some are becoming untreatable. Antibiotics should be treated like oil, a non-renewable resource (Haddox, 2013).
The phenomenon of antibiotic resistance occurs when bacterial organisms can resist – via several different avenues – the harmful effects of antibiotic drugs, which ultimately results in a selective advantage that is not shared amongst the remainder of the population that is still susceptible to the effects of the drugs. There are numerous ways that bacteria are known to show resistance to antibiotics. Some bacteria can modify the chemical nature of the drug, making it ineffective, and yet some possess a different form of target site that the drug is not compatible with, which inhibits the drug’s ability to bind to the bacterial cell. When coupled with prevalent antibiotic use amongst human populations, these acquired mechanisms of resistance can be selectively advantageous to the bacteria in possession of them. Being resistant to one or more antibiotic drugs means that these bacteria can survive and pass on their genes for resistance to their offspring, which can have negative effects on human populations, especially in the healthcare setting. Antibiotic resistance has garnered much attention in recent years across the developed world, as pathogenic microbes become resistant to more and more antibiotics thanks to both the overuse and misuse of these drugs. The increased frequency of which this problem has
The overuse of antibiotics has been a problem for well over a decade. This misuse leads to many nonvisible problems arising within the human population. As the use of antibiotics increases, the number of antibiotic resistant bacteria also increases. When bacteria become resistant to an antibiotic, another antibiotic must be used to try and kill it and the cycle becomes vicious. Michael Martin, Sapna Thottathil, and Thomas Newman stated that antimicrobial resistance is, “an increasingly serious threat to global public health that requires action across all government sectors and society” (2409).
The question of antibiotic resistance is a growing phenomenon in contemporary society and modern medicine; it pertains to pathogenic organisms and is one of the most eminent issues of public health in the twenty-first century. Though resistant genes are ancient, its increasing prevalence poses a threat. It demands a greater need for antibiotic therapies. New resistance mechanisms may spread globally and limit our ability to treat disease and lead to a giant hole in the pillars of modern medicine.