Rheumatoid Arthritis Research Paper

Rheumatoid Arthritis(RA) is the most common type of autoimmune arthritis. RA is a progressive and debilitating musculoskeletal disorder that affects the joints symmetrically, causing a range of systemic effects. What it causes is still not well known; nevertheless, findings of new research points towards a believe that it is triggered by a defective immune system, which causes the release of inflammatory chemicals. These chemicals cause damage to cartilage and bone, usually affecting the wrists, the joints of the hand, including the knuckles, the middle joints of the fingers and feet. While this condition can affect any joints, besides, important body organs such as the eyes and the lungs can also be affected by the inflammation that occurs as a result of this chronic condition. Only in America 1.3 million of people are affected by this ailment, and 75 % of them are mainly women. Its onset usually occurs between fourth and sixth decades; however, RA can occur at any age("Diseases And

Rheumatoid Arthritis has been subject of numerous studies and researches in the look for a better understanding of how it effects the individuals diagnosed with it. There is a higher incident of females diagnosed with RA than male as well as a relationship with genetic and environmental factors involved. Around one percent of the world population is affected by RA; therefore, diverse studies have been performed to understand how the lives of the diagnosed patients can be impacted by the disease. For example, how RA affects the mobility, safety and activities of daily living in general as well as the development of interventions to better approach RA. On

Rheumatoid Arthritis or (RA) is an autoimmune disease that attacks the joints and connective tissue. The result is inflammation that produces permanent damage in the joints. Rheumatoid arthritis is a chronic syndrome that tends to be progressive and destructive as compared to Osteoarthritis or (OA), which is more of an age related disease caused by “wear and tear” of the joints. In contrast to (OA), rheumatoid arthritis is characterized by inflammation mostly of the joints, but is a general body disease.

Most evidence today support the concept that the pathology of rheumatoid arthritis has its bases in an inflammatory response involving the immune system. Other theory of causation include genetic factors, infectious agents and an antigen-antibody response. It is unlikely that a single factor is responsible for all cases of rheumatoid arthritis.

Rheumatoid arthritis is a systemic disease that affects whole systems of body particularly cardiovascular system, nerves, respiratory system (RACGP, 2009). The causes of rheumatoid arthritis are unknown but it is hereditary which assists to have a risk of rheumatoid arthritis by 50%-60% (RACGP, 2009).

Rheumatoid arthritis is a chronic syndrome that is characterized by inflammation of the peripheral joints, but it may also involve the lungs, heart, blood vessels, and eyes. The prevalence of this autoimmune disease is between 0.3% to 1.5% of the population in the United States (Feinberg, pp 815). It affects women two to three times more often than men, and the onset of RA is usually between 25 and 50 years of age, but it can occur at any age (Reed, pp 584). RA can be diagnosed by establishing the presence of persistent joint pain, swelling in a symmetric distribution, and prolonged morning stiffness. RA usually affects multiple joints, such as the hands, wrists, knees, elbows, feet, shoulders, hips, and small hand joints. RA is

Rheumatoid arthritis is an autoimmune disease that accounts for roughly 0.6% of the population in the United States. The disease typically affects the elderly, but also affects older teenagers, young adults and affects women three times more than men. Rheumatoid arthritis is when a person’s immune system to attack the synovial membranes of the joints and causes inflammation. The genetic link of rheumatoid arthritis is not completely clear. However, it has been shown that having a family member with rheumatoid arthritis will increase the risk of developing the disease. There are currently two genes being looked at that has shown to be involved in the development of rheumatoid arthritis, HLA-DRB1 and PTPN22. These were discovered by looking at

The process involves an inflammatory response of the capsule around the joints (synovium) secondary to swelling (hyperplasia) of synovial cells, excess synovial fluid, and the development of fibrous tissue (pannus) in the synovium (Gerd et al.,2014). RA is more prevalent among women than men, and usually develops in the fourth and fifth decades of life, with 80% of the total cases occurring between ages 35 and 50 (Kavanaugh and Lipsky 1996).RA reduces lifespan on average from three to twelve years. RA is associated with decreased physical function, disability, under employment, and overall diminished quality of life. (Maclean C H et al., 2000). When it occurs in children it is called Juvenile Rheumatoid Arthritis. The incidence and prevalence of RA differs significantly over time and between continents. The prevalence in developing countries ranges between 0.1 and 0.5% (Akar et al., 2004). Rheumatoid arthritis (RA) is a chronic systemic inflammatory illness with prevalence of approximately 0.75% in India (Ausaf et al.,

Rheumatoid arthritis or (RA) can be difficult to diagnose for several reasons and there are many ways to diagnose it. Since there is no single test for the disease, there are just three ways to specify whether the patient has the disease or not. In addition, the symptoms of rheumatoid arthritis and other types of arthritis diseases can be similar that makes the diagnosing process inaccurate. Moreover, the symptoms vary from patient to another and it develops over time, so it can be severe in some people than the others can. As a result, doctors use several ways to diagnose this disease and to rule out the others. At the beginning, doctors always ask the patients to describe the symptoms and if it changed over time or not. In addition, they

Rheumatoid arthritis is a chronic autoimmune disease that is characterised by the inflammation of the joints, often accompanied by deformities. Moreover, rheumatoid arthritis is a gradual condition, developing over several months and years. Furthermore, diagnosis of rheumatoid arthritis the moment its symptoms appear is vital for its treatment and prevention. Considering the fact that rheumatoid arthritis has no exact cause and no known cure, many people are participating in rheumatoid arthritis clinical trials.

Rheumatoid arthritis (RA) is a chronic inflammatory disorder that typically affects the small joints in the hands and feet. Unlike the wear-and-tear damage of osteoarthritis, RA affects the lining of the joints, causing a painful swelling that can eventually result in bone erosion and joint deformity. In America, RA is the most common form of autoimmune arthritis, affecting more than 1.3 million Americans. Of these, about 75% are women. The disease most often begins between the fourth and sixth decades of life. However, the RA also can start at any age. In Malaysia, RA affects about 5 in 1000 people. According to Malaysian Statistic on Medicine in 2005, the total drug expenditure in 2005 for the treatment of inflammatory and rheumatic diseases was RM 50.7 million, and form 7.8% of the top 40 prescribed drugs in Malaysia. It was ranked 5th as the highest prescribed group of drugs (MOH, 2004).

The diagnosing steps have been directed, practitioners check everything and gets the conclusion based on the whole results they have got. Other doctors take more signs based approach to try to diagnose the Rheumatoid Arthritis while other they only use the blood tests and medical history of the patients just to confirm a diagnostic of Rheumatoid Arthritis. It came in to real conclusion why it is very possible with diagnosis and prognosis of Rheumatoid Arthritis even though it does not test positive for those antibodies or have medical history of Rheumatoid Arthritis in your initial family. If it happens that symptoms themselves are very consistent with the disease Rheumatoid Arthritis, then it can also be diagnosed. So in this case there is generally two classifications ofRheumatoid Arthritis. Somehow the given criteria for diagnosing Rheumatoid Arthritis must exactly include the existing illustrations of signs for more

According to research, rheumatoid arthritis (RA) is the most popular autoimmune disease. RA is known to be a prolonged, systemic disease that causes inflammation. This inflammation can potentially disturb the synovial tissue that is in the body which eventually leads to damage in the joints, disabling functional abilities, and sometimes even leading to death. Many different factors can be held accountable for the diagnosis (Korczowska, 2014). Throughout this display of research many different ranges of aspects will be discussed. This illness is seen in tremendous amounts amongst physical therapy. The etiology, which happens to be the cause of this case of arthritis, and the signs and symptoms, will be revealed. Certain medical and

Rheumatoid arthritis (RA) is characterized by chronic, erosive polyarthritis and the presence of numerous autoantibodies in the serum and synovial fluid and membrane. Rheumatoid arthritis (RA) is a systemic inflammatory autoimmune disease that manifests in multiple joints of the body. The inflammation leads to erosions in the cartilage and bone and can cause joint deformity. Individuals with RA often experience pain and swelling of the joints. It was estimated in 2005 that 1.5 million people in the United States were afflicted with RA. There are three times as many women than men affected with RA (CDC, 2015).

According to, Eichenfield, Athreya, Doughty, Cebul, Juvenile Rheumatoid Arthritis is more common in young girls. The patients that are diagnosed with this disease are more likely to have “roentgenographic” evidence of bony erosion and worse prognosis.