Research Paper On Sickle Cell Anemia

Sickle cell anemia occurs when a person inherits two abnormal genes (one from each parent) that cause their red blood cells to change shape. Instead of being flexible and round, these cells are more rigid and curved in the shape of the farm tool known as a sickle - that's where the disease gets its name. The shape

Sickle Cell Disease is an illness that affects people all across the globe. This paper will give a description of the sickness through the discussion of the causes, symptoms, and possible cures. Sickle Cell Disease (SCD) is a "group of inherited red blood cell disorders."(1) These disorders can have various afflictions, such as pain, damage and a low blood count--Sickle Cell Anemia.

Sickle Cell anemia is a group of inherited red blood cell disorders, or a collection of recessive genetic disorders characterized by a hemoglobin variant called Hb S. Normal red blood cells are round like doughnuts, and they move through small blood tubes in the body to deliver oxygen. Sickle red blood cells become hard, sticky and shaped like sickles used to cut wheat. When these hard and pointed red cells go through the small blood tube, they clog the flow and break apart. This can cause pain, damage and a low blood count, or anemia. There is a substance in the red cell called hemoglobin that carries oxygen inside the cell. One little change in this substance causes the hemoglobin to form long hard rods in the red cell when it gives

Sickle Cell Anaemia is a heredity disorder in which the red blood cells are affected by altering into a mutated-form of haemoglobin, most commonly at low oxygen levels. The altered-form of haemoglobin are crescent-shape; which are not flexible and can easily block the blood flow in smaller blood vessels and arteries (refer to figure 1). When both alleles inherited carry the sickle cell anaemia disease; 100% of the body’s haemoglobin will mutate into the sickle (crescent) shape. Sickle cell disease is the codominance of only one inherited sickled allele, in which; the carrier can pass the disorder but does not express any significant symptoms or the anaemia itself. Sickle cell anaemia is an autosomal recessive disorder, thus both alleles must

Sickle cell anemia can cause numerous symptoms, which the severity of this can vary between individuals. Symptoms that might vary from person to person that change over time, include anemia, episodes of pain, frequent infections, delayed growth, vision disorder, acute chest syndrome, and more. Indeed, of each symptom; anemia, sickle cell breaks red blood cell faster and die living people without enough red blood cells. Sickle cell anemia usually dies in 10 to 20 days while normal live for about 120 days before it replaced. Episodes of pain is a major symptom of this disease and the most common reason for people to get hospitalization; Pain develops when sickle-shaped red blood cells block blood flow through tiny blood vessels to the chest,

The term sickle cell infection (SCD) depicts a gathering of acquired red platelet issue." Normal red blood cells are shaped like discs or donuts. They are soft and flexible so they can easily move through very small blood vessels"(anonymous, 2015).Individuals with SCD have anomalous hemoglobin, called hemoglobin S or sickle hemoglobin, in their red platelets. Hemoglobin is a protein in red platelets that conveys oxygen all through the body. The most well-known sort is known as, sickle-cell frailty (SCA) and there is A few Types of Sickle Cell Sickness: Hemoglobin SS, Hemoglobin SC, Hemoglobin SD. In the Unified States, a great many people with sickle cell illness (SCD) are of African family line or recognize themselves as dark. About1 out of 13 African American children is

Normal red blood cells are flexible and round and last up to four months. Sickle red blood cells are hard and sticky and looks like farm tool called a “sickle”. These cells die within twenty days which

Signs and symptoms of sickle cell disease usually begin in early childhood. Sickle cell disease is a group of disorders that affects hemoglobin, the molecule in red blood cells that delivers oxygen to cells throughout the body. Characteristic features of this disorder include a low number of red blood cells or anemia, repeated infections, and periodic episodes of pain. The severity of symptoms varies from person to person. Some people have mild symptoms, while others are frequently hospitalized for more serious complications. Infections are common with sickle cell such as infections in the urine making it unclear and sometimes bloody. It can also cause pain in the joint. This pain is why most victims of sickle cell anemia say their bodys are always sore and uncomfortable. Lastly, people who have the disorder tend to be fatigued and majorly lazy do to the lack of energy due to their aching

The disease that I will be writing my report on is called, Sickle Cell Disease. Sickle cell disease is a disorder that affects the red blood cells, which use a protein called hemoglobin to transport oxygen from the lungs to the rest of the body. The reason I chose Sickle Cell Disease because it is occurred in mostly African-American, South America, and Caribbean islands. Also, Sickle Cell runs in my family so I thought this would be a good idea to write about it and let my class know what I know. Sickle Cell is a blood disorder. Normal blood cells and sickle cell blood cell are two totally different things. Normal blood cells are round, flexible that means they can travel through small blood vessels. Sickle cell disease causes the red blood cells to form into a crescent shape,

In fact there is a vast number of different Sickle Cell disease. The most recognized types of Sickle Cell Disease are Hemoglobin SS Disease, Hemoglobin SC Disease, Hemoglobin SB+ Thalassemia, and Beta-Zero Thalassemia. Hemoglobin SS Disease also known as Sickle Cell Anemia is the most common form of Sickle Cell Disease. Sickle Cell Anemia occurs when the patient inherits two genes that are abnormal and causes the shape of the red blood cell to alter. Hemoglobin SC disease is known as a Hemoglobinopathy. Hemoglobinapathy is a hereditary condition involving the abnormal form of hemoglobin. Hemoglobin SB+ Thalassemia is said to be a variant form of Sickle Cell Anemia. The final common form of Sickle Cell is Beta-Zero Thalassemia. Beta-Zero Thalassemia like Hemoglobin SB+ Thalassemia is similar to Sickle Cell Anemia. These different types of Sickle Cell vary from the type of symptoms and the different types of

Complications of sickle cell anemia are pain crisis, infection, acute chest syndrome, splenic sequestration, vision loss, leg ulcers, stroke, deep vein thrombosis and pulmonary embolism. Pain crisis is a feeling of pain that can happen all of the sudden with mild to severe intensity and last for a period of time (“Facts About Sickle Cell Disease,” 2016). Serious bacterial infections are potential life threatening due to the damage to the spleen in some people who have sickle cell anemia (https://www.nhlbi.nih.gov/health/health-topics/topics/sca/signs). Acute chest syndrome can be life threatening and symptoms included chest pain, coughing, difficulty breathing, and fever. Splenic sequestration is can be life threatening

In most cases, people with sickle cell begin experiencing symptoms at the age of 4 months’ symptoms include fatigue which happens due to the loss of red blood cells after they rupture as they are extremely fragile. Another symptom will be the pain, it develops when other is a blockage within the blood vessels in your chest, abdomen, and joints. Intensity varies and can even lead to hospitalization. Delayed growth and vision problems of blood cells blocking areas of the body. You are more prone to infections and will also experience swelling of the hands and feet.

The sickle cell disease is an inherited blood disorder that affects red blood cells. People with sickle cell have red blood cells that have mostly hemoglobin's, Sometimes these red blood cells become sickle-shaped or crescent shaped and have trouble going through small blood vessels. When sickle-shaped cells block small blood vessels, less blood can get to that part of the body. Tissue that does not get a normal blood flow eventually becomes damaged. This is what causes the problems of sickle cell disease.

Sickle Cell Disease is an autosomal recessive genetic disease that occurs due to a mutation in the β-globin gene of hemoglobin. Autosomal meaning that it is not linked to a sex chromosome, so either parent can pass on the gene to their child. This mutation is a result of a single substitution of amino acids, Glutamic for Valine at position 6 of a β globin chain. The presence of this mutation causes

Sickle Cell Anemia is a disease that affects how oxygen is carried throughout the body by blood. Specifically, sickle cell anemia is characterized by a change in the shape of red blood cells from a smooth donut shape to a crescent or sickled shape, almost the same shape as a crescent moon. The sickled cells are very long and stiff, so sometimes