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Polycystic Kidney Disease

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Polycystic Kidney Disease, also referred to as PKD, is an inherited disorder characterized by the growth of abnormal fluid-filled cysts in the kidneys (NKUDIC). There are two types of PKD, Autosomal Dominant and Autosomal Recessive, these depending on the genes of the client’s parents. PKD is a chronic, incurable disease that can lead to further renal complications including end stage renal disease and uremia. Approximately 600,000 Americans are affected by PKD, according to the Kidney and Urologic Diseases Statistics for the United States: NIDDK.
It is thought that PDK is caused by mutations of the genes on chromosome 16 or chromosome 4. The disease process begins with the appearance of cysts, which grow out of the nephrons of the kidneys. …show more content…

Diagnostic exams for PKD are commonly kidney imaging studies, including ultrasounds, CT scans, and magnetic resonance imaging (NKUDIC). According to the NKUDIC, “diagnosis can also be made with a genetic test that detects mutations in the autosomal dominant genes.” Autosomal recessive PDK is diagnosed using ultrasound images of the fetus or newborn, revealing enlarged kidneys or kidneys with an abnormal appearance. It has also been found that higher serum uric acid levels are associated with Polycystic Kidney Disease, according to …show more content…

When/if transplantation is not an option, medical management primarily focuses on relief of symptoms. Pain is managed by pain medications such as aspirin and acetaminophen. Urinary tract infections are controlled by antibiotics. Lifestyle changes and various antihypertensives are used to maintain normal blood pressure. In some cases, surgeons will attempt to remove cysts surgically, but it is only a temporary treatment, for cysts will regrow. When a PKD patient is faced with the complication end stage renal disease, their only two options are dialysis and transplant. “If serious liver disease develops, some people can undergo combined liver and kidney transplantation” (NKUDIC). When a transplant is performed, the donor kidneys will not develop

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