BENEFIT OF PHYSICAL TRAINING IN PATIENTS WITH DIABETES AND CHRONIC KIDNEY DISEASE. Yetunde M. Fajulugbe Department of Pharmacology and Toxicology, Boonshoft School of Medicine, Wright State University Dayton OH. Keywords: Diabetes, Chronic Kidney Disease, Physical Training, Abstract: Introduction Diabetes occur when there is a combination of inadequate secretion of insulin by the pancreatic beta cells and the peripheral insulin resistance. Insulin resistance leads to a reduced glucose transport into the muscle cells, increases both hepatic glucose production and breaking down of fats because it has been attributed to the elevated level of free fatty acids and proinflamatory cytokines in the plasma.1 Major factor across the spectrum of prediabetes to diabetes is the beta cells dysfunction, there is an early development in the beta cells dysfunction in the pathological process and may not certainly follow the insulin stages.2 According to the report from the center for disease and prevention (CDC) in 2011, nearly 26million Americans are suffering from Diabetes.3 Furthermore, CDC reported in 2014 that there are chances of 40% American adults developing diabetes in their lifetime and half of the ethnic minorities will be affected. It is worthwhile to note that obesity was reported as the reason for the tremendous increase.4 Chronic kidney disease (CKD) is a common disorder and occurs in the elderly population. In younger patients, it
Diabetes affects over 180 million people in the US and is projected that by 2025 this figure will increase to 300 million.
Chronic Kidney Disease (CKD) is a disease that is described as a loss of kidney function gradually over time. As kidney function decreases, the waste collection in the body’s blood becomes high and makes the individual feel sick. This disease can lead to other complications in the body such as anemia, poor nutritional health, high blood pressure, and nerve damage. These complications will begin to progress and show as CKD progresses to advanced stages. Early detection of this disease is essential when it comes to treatment. If CKD is diagnosed early enough the disease progression can be slowed down and managed. This disease will eventually lead to failure of the kidneys
Chronic kidney disease (CKD) is a worldwide problem that is currently three times higher for African Americans, Hispanics, Pacific Islanders, American Indians and seniors (The National Kidney Foundation, 2013). CKD occurs when the kidneys are damaged by a pathogen or injury and they can no longer adequately maintain proper levels of regulated chemicals in the bloodstream. There are many risk associated with CKD. According to the National Kidney Foundation, two of the major risks are Chronic Renal Failure (CRF) and Cardiovascular Disease. Currently twenty million American adults have CKD and millions of others are at increased risk. Age has no barrier on getting CKD. People with pre-existing health issues, and a part of certain population
Diabetes is a major medical problem in the US. In the year 2015, it was reported that 86 million Americans are diagnosed with prediabetes (ADA, 2016). Diabetes is the seventh leading cause of death in the United States (CDC, 2016). Research has
According to the National Kidney Foundation (2012a), everyone is at risk for CKD. Although certain populations of people, diabetics and people with HTN, are at a higher risk, a person may be diagnosed with CKD at any age (National Kidney Foundation, 2012a); therefore, it is important for adults at risk for or diagnosed with CKD and their families to understand how to prevent and care for the CKD because how effectively a person copes with the disease depends on how much support they can receive not only from the health care team but also from
The American Diabetes association (2014) reports that, approximately 29.1 million U. S. residents are diabetic. They found that 35% to 40% of people died from diabetic related causes. 2010 saw 69,071 death certificate reported deaths listing diabetes as the direct/underlying cause of death, while, 234,051 death certificates lists diabetes as the underlying/contributing cause of death. Diabetes still remains the 7th leading cause of death in the United States.
Chronic kidney disease is that is a decline in the function of the of the renal system due that can be measured by the glomerular filtration rate. Long term complication can lead to end stage renal failure which places patient to be on long-term dialysis. The incidence of chronic kidney is on a constant rise. The main cause of chronic disease is diabetes in combination with hypertension. In the United States, there are an estimated 25 million people who have been diagnosed with chronic kidney disease (CKD), and the prevalence is especially high among the elderly with approximately ten million cases in those over the age of 77. The purpose of this paper is to describe the clinical presentation of chronic kidney disease and describe potential factors that may impact the diagnosis and include treatment options.
Diabetes mellitus is related to the hormone insulin, which is secreted by the beta cells of
Chronic Kidney Disease (CKD) is among the leading causes of mortality throughout the world, and its prevalence and the health care costs resulting from it are considerable and increasing. CKD commonly is silent and asymptomatic until its late stages. Accordingly, CKD is diagnosed prior to symptomatic stage of kidney failure, resulting in delays in proper interventions and the emergence of adverse consequences in the CKD patients
Chronic Kidney Disease (CKD) is emerging as a major challenge for the global health-care systems with increasing life-expectancy and rising rates of obesity, diabetes and hypertension (1). Not surprisingly, the incidence-rates of End-stage Kidney Disease (ESKD) have been rising world-wide with rates ranging from 12 to 455 per million population (pmp) (1). ESKD affects 107 individuals per million population in the United Kingdom (2). Although the incidence-rates have been stable from 2006-2010, it has risen from 95pmp in 2001 (2). Prior to the 1960’s when dialysis was available, ESKD was universally fatal. Since the advent of dialysis, ESKD was no longer a terminal condition. With evolving technologies and modifications of the techniques, dialysis developed into a long-term treatment for ESKD. However, survival, morbidity, and quality of life remain poor, while cost stays high.
Chronic Kidney Disease (CKD) is rising in incidence and prevalence placing a significant burden on healthcare resources worldwide. CKD is estimated to affect >10% of the global population, and is currently listed among the leading causes of death in the developed world (ranked ninth by WHO global health) with deaths attributable to CKD is expected to continue to rise. CKD is associated with comorbidities including anaemia, bone disease, diabetes and is recognised as an important risk factor for cardiovascular disease and cancer.
Chronic kidney disease (CKD) is a condition characterized by a gradual loss of kidney function over time (kidney.org, 2015). Renal failure is a complex and challenging health issue that demands the involvement of both specialists and primary care providers (Buttaro, Trybulski, Polgar, Bailey, & Sandberg-Cook, 2013). In this paper I will discuss what chronic kidney disease is, how it is diagnosed, and what treatment options there are, as well as how potential patient factors can impact diagnosis and treatment of chronic kidney disease.
Chronic kidney disease (CKD) is a leading cause of the critical mortality and morbidity, the Global Burden of Diseases 2010 study reported that CKD contributes to approximately 740,000 deaths annually, making it the 18th leading cause of death (Benigni et al. 2010, Lozano et al. 2012). CKD is a progressive condition as either kidney damage or decreased kidney function over time (Figliuzzi et al. 2014). The main causes of CKD include glomerulonephritis, diabetic kidney disease, hypertensive nephropathy, polycystic kidney disease and other factors, which gradually decrease the glomerular filtration rate (Karczewski and Malkiewicz. 2015). The major outcomes of CKD include progression to kidney failure, complication of decreased kidney function, and cardiovascular disease. Moreover, patients with CKD are at high risk for progression to the end stage renal disease (ESRD) (Levey et al. 2003). The increasing number of patients with CKD, medicare spending on these patients exceeds $29 billion annually and expecting an expense of almost 3~5% of annual healthcare budgets in Unite state (Collins et al. 2012, Burgkart et al. 2014).
Since nephropathy is linked with hypertension, providers should closely monitor blood pressure (ref). Diabetic kidney disease may be preventable, so it is important for pediatric health care professionals to understand screening, risk factors, prevention, and treatment options.
Statistics list that a little over two hundred thousand United States citizens that range under the age of twenty have been diagnosed with diabetes. Varying between age groups it is believed that around eighteen thousand citizens have been diagnosed with type 1 diabetes and a little over five thousand have been diagnosed with type 2 diabetes. It is suggested that because of our eating habits in the United States