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Benefits Of Physical Training Patients With Diabetes And Chronic Kidney Disease

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BENEFIT OF PHYSICAL TRAINING IN PATIENTS WITH DIABETES AND CHRONIC KIDNEY DISEASE. Yetunde M. Fajulugbe Department of Pharmacology and Toxicology, Boonshoft School of Medicine, Wright State University Dayton OH. Keywords: Diabetes, Chronic Kidney Disease, Physical Training, Abstract: Introduction Diabetes occur when there is a combination of inadequate secretion of insulin by the pancreatic beta cells and the peripheral insulin resistance. Insulin resistance leads to a reduced glucose transport into the muscle cells, increases both hepatic glucose production and breaking down of fats because it has been attributed to the elevated level of free fatty acids and proinflamatory cytokines in the plasma.1 Major factor across the spectrum of prediabetes to diabetes is the beta cells dysfunction, there is an early development in the beta cells dysfunction in the pathological process and may not certainly follow the insulin stages.2 According to the report from the center for disease and prevention (CDC) in 2011, nearly 26million Americans are suffering from Diabetes.3 Furthermore, CDC reported in 2014 that there are chances of 40% American adults developing diabetes in their lifetime and half of the ethnic minorities will be affected. It is worthwhile to note that obesity was reported as the reason for the tremendous increase.4 Chronic kidney disease (CKD) is a common disorder and occurs in the elderly population. In younger patients, it

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