Pernicious Anemia Research Paper

As a provider, one will care for many patients that have different types of anemia. Anemia is not so much as a disease as a symptom of an underlying issue. Although there can be particular signs and symptoms associated with anemia, the basis of a diagnosis is from laboratory data. For the purpose of this discussion, I will evaluate a case study and give a differential diagnosis. I will also assess how patient history, physical exam, and lab reports support my diagnosis. I will explain the pathophysiology of the type of anemia and give causes and treatment options available.

1. Anemia, pp. 989. Anemia is a areduction in the total number of erythrocytes in the circulating blood or a decrease in the quality or quantity of hemoglobin. Anemias commonly result from (1) impaired erythrocyte production, (2) blood loss (acute or chronic), (3)increase erythrocyte destruction, or (4) a combination of these three. sThe fundamental physiologic manifestation of anemia is a reduced oxygen-carrying capacity of the blood resulting in tissue hypoxia.

Iron deficiency anemia, one of the most common types of anemia, is a blood disorder where

Yearly, around six hundred to nine hundred people are diagnosed with Aplastic Anemia within the United States. Aplastic Anemia is a autoimmune hematological disorder that causes pancytopenia which is a reduction in major blood components, namely, erythrocytes, leukocytes and platelets. This disease has been labelled as a type of bone marrow failure, that is often due to not one but a variety of disorders that occur simultaneously. Aplastic Anemia can therefore be defined as a bone marrow disorder that is often rare, non contagious, and can often be life threatening.

Sickle cell anemia has a less serious condition known as Sickle Cell traits. This is a heterozygous condition where less than half of the number of red blood cells is sickle shaped while the rest are normal and they are involved inefficient oxygen loading. An individual with the sickle cell trait experiences a mild case of anemia but always leads a normal life. Treatments that have been prescribed for the sickle cell condition include medication as well as blood transfusions and rarely a bone-marrow

Sickle cell anaemia (sickle cell disease) is a disorder of the blood caused by an inherited abnormal hemoglobin (the iron-rich protein that carries oxygen from your lungs to the rest of the body).

Pernicious anemia is the etiology of vitamin B12 deficiency due to the lack of production of an intrinsic factor (IF), altered pH in the small intestine, and lack of absorption of B12 complexes in the terminal ileum as well as folic acid deficiency. Impairment of IF production can occur in adults due to autoimmune destruction of parietal cells, which secrete IF; gastrectomy can significantly reduce the production of IF. A rare congenital autosomal recessive disorder can result in deficiency of IF without gastric atrophy. Other disorders that interfere with the absorption and metabolism of vitamin B12 can produce cobalamin deficiency, with the development of a macrocytic anemia and neurologic complications. Some autoimmune diseases such as Graves' disease, Hashimoto's thyroiditis and vitiligo the depigmentation or blanching of skin areas. (Center Disease Control &Prevention (CDC), 2015)

Sickle Cell Anemia is a hereditary disease that has a gene that causes red bone marrow in the body to make sickled shapes, when this happens; it causes the red blood cells to die faster. This is what causes Hemolytic Anemia. Older children and adults with sickle cell disease may have very few complications, or have patterns of ongoing problems that ultimately shorten their lives. The most serious and common problems with sickle cell disease are organ failure, fatigue and pain. There are many opportunities and alternatives for treatment and symptom management that a sickle cell patient can consider today.

This paper outlines the etiology of sickle cell anemia and the nutrition considerations that is needed to maintain this disease. It also provides a five day menu plan that will greatly provide nutrition needs to prevent having a sickle cell crisis.

In 1872 Michael Anton Biermer described a blood condition in a German article. He chose to name the rare disease he discovered “Pernicious anemia” because of the lethality and incurability at the time. Biermer’s disease or Pernicious anemia is a genetic disease where patients’ stomachs do not produce intrinsic factor which is a protein of the mucus membrane layer of the stomach.When the stomach does not make enough intrinsic factor, the intestine cannot properly absorb vitamin B12. The body needs vitamin B12 in order to function properly and remain healthy. Vitamin B12 assists in the production of red blood cells, DNA, and tissues, while helping keep nerve cells alive and healthy.This vitamin is found in many animal products such as beef, poultry, shellfish and more.

I was surgery last month. After surgery, my doctor told me I had an amount of blood. So, I felt very tired. I become more interested in anemia. Accordingly, I had picked iron deficiency anemia. According to the Health line, anemia occurs when I have a level of red blood cells (RBCs) in my blood that is lower than normal. They explained iron deficiency anemia that is the most common type of anemia, and it occurs when my body do not have enough of the mineral iron. My body needs iron to make a protein called hemoglobin. This protein is responsible for carrying oxygen to my body’s tissues, which is essential form my tissues and muscles to function effectively. When there is not enough iron in my blood stream, the rest of my body cannot get the

Doreen Flynn is a mother of five children living in Maine. Three of her girls, Jordan, Jorja, and Julia, have a severe form of a life threatening disease called Fanconi anemia. Fanconi anemia is a recessive genetic disorder that interferes with normal blood cell production and causes deficiencies with organ growth. A victim will often have abnormalities in the heart, lungs, bones, spine, kidneys, eyes and ears from the lack of healthy blood. It also puts he or she at an extremely high risk for developing several different types of cancer. Medications and hormone therapy can be used to help a child survive for a while, but ultimately, a bone marrow transplant is needed.

Anemia is a medical condition defined as having low amounts of red blood cells, thus transporting low levels of oxygen in the blood. Common symptoms include fatigue, weakness, and shortness of breath. Causes for anemia vary, depending on the severity and duration of illness. Regular anemia can result with low levels of iron in the blood. (Mayo Clinic, 2014)

Anemia is a disorder of the blood. It occurs when your body does not produce enough erythrocytes or red blood cells (RBCs). Without the erythrocytes oxygen can not be adequately delivered to the tissues and organs throughout the body. This will cause you to become weak and tired. A person may also experience headaches, skin pallor, and faintness. Your body may attempt to compensate for these symptoms by speeding up the heart rate and respiratory rate. This is the body’s attempt to return oxygen levels to normal(Thibodeau and Patton, 2005).

Introduction:Fanconi anemia or FA, is first described in 1927 Guido who was a Swiss paediatrician. FA is a rare inherited blood disorder that causes to bone marrow failure. FA prevents bone marrow from making enough new blood cells necessary for our body and cause to make many defective blood cells. FA is a blood disorder that can be inherited as Autosomal recessive disorder ,also in some cases it can be inherited as an X-linked recessive condition. It affect many of our body's organs, tissues and system. Children who inherit FA have a higher risk of being born with birth defects.FA is one of many types of Anemia that refers to a condition to lower red blood cells in the body.