Meta Description Ovation Fertility is proud of our Nashville genetics lab, which offers our patients PGD using FISH and CCS under the director of Amy Jones, MS.
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Ovation Fertility™ Nashville Genetics Lab
The Ovation Fertility Nashville genetics lab offers comprehensive genetic testing and screening of embryos
Aneuploidy, or an incorrect number of chromosome, is a common occurrence, even in embryos that look normal and healthy. When an embryo with an incorrect number of chromosomes is transferred, it will result in IVF cycle failure, miscarriage or birth defects. To avoid this heartbreak, our Nashville genetics lab is proud to offer a state-of-the-art genetics lab that provides preimplantation genetic
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• FISH stands for fluorescent in situ hybridization, and it does not test all chromosomes. FISH can only test 13, 15, 16, 17, 18, 21, 22, X and Y, because these chromosomes are most commonly associated with miscarriages, failed IVF cycles, and genetic abnormalities caused by advanced maternal age. The testing is 90-95% accurate, and we recommend it for all patients undergoing IVF.
• CCS, or comprehensive chromosome screening, and it has many advantages over FISH. This testing method can screen all 24 chromosomes, and current information suggests that CCS leads to better implantation and live birth rates. Our Nashville genetics lab recommends CCS for patients with a history of failed IVF cycles, recurrent miscarriage or advanced maternal age.
Our Nashville genetics lab can help you get started with PGD
If you’re considering PGD with our Nashville genetics lab, you should first schedule an appointment with an Ovation Fertility partner physician. You will then schedule a consultation or class with the director of preimplantation genetic diagnosis at our Nashville genetics lab Amy Jones,
Therapeutic genetic manipulation is preformed by doctors to prevent diseases that the baby is carrying. The baby is tested by screening the embryo for any possible unknown diseases. Sometimes the PGD or preimplantation genetic diagnosis technique is used for this ("Biotechnology special focus"). The main diseases PGD is used to test for in babies are Hunntington's disease, Tay-sacks, Alzheimers, Familia cancers, Sickle Cell disease, Hemophilia, Neurofibromatosis, Fanconi's Anemia, Cystic fibrosis and most recently, Down's Syndrome ("Hooray for designer babies", 2002). This technique involves removing the unfertilized egg from the female, mating it with a sperm and then testing it for diseases. If all the diseases are absent, the fertilized egg is planted into the mother's uterus to develop into a baby. Some other unpredictable diseases may also be carried in the baby's chromosomes. Chromosome carrying diseases and disorders include: miscarriage of the baby, physical birth defects or down syndrome (Biotechnology special focus").
Making big choices in life can be difficult, especially if that big choice is having children. There are many men and women who are infertile that still want to have children. Most decide to adopt other children who do not have families or their families do not want them. But when adoption is not an option, there is now a way where those men and women can have their own children together through fertility treatments. Fertility treatments could be a good thing:being able to freeze egg and sperm, they can help infertile couples, and avoiding transmitted diseases would be easier.
Dr. Schiewe is the high complexity lab director at Ovagen Fertility Newport Beach and the scientific laboratory director at California Cryobank. Over the last three decades, he has helped IVF labs worldwide protect and transfer embryos in the blastocyst stage and improve pregnancy rates. Dr. Schiewe has published over 35 peer-reviewed papers and 70 abstracts. He also serves as a journal reviewer for Fertility and Sterility and Theriogenology. For more information about Dr. Schiewe and his work, please visit
Modern medicine now relies more and more on genetic science, so the demand for health care professionals who can assess and communicate these health issues is significantly increasing. This is because public awareness is growing in conjunction with scientific advances in reproductive technologies. Health care consumers now want genetics specialists who can provide highly accurate and advanced consultations regarding their unique genetic conditions. Most genetic counselors work with couples or single mothers who
As of 2009, selecting for the sex of a child was already feasible since it requires only identifying an X or Y chromosome, but selecting for nonmedical traits was not due to the amount of genetic material required, and one example has been described where a deaf couple used PGD to select for a deaf baby.
After the failure of several fertility treatments the couple signed up for new-generation sequencing [NGS] (Sample, 2013, para.5). Sample (2013, para. 6) states that, “Abnormal chromosomes account for half of all
Infertility is the fundamental lacking of the ability to conceive a baby, and both men and women can have this problem. Dr. Clark, our guest speaker in class pointed out that approximately 30% of men and women are infertile, while 25% of infertility cannot be explain by science yet. Because of that, infertility is no longer considered as a lifestyle problem but a disease instead. According to Dr. Clark, one of the options for the infertility patients today is the use of stem cell therapies to treat infertility, and one of the recent popular stem cell therapies is reproductive cloning. Reproduction cloning is a process to “produce” a next generation of “you” through somatic cell nuclear transfer. In my paper, I will argue that
Ammonium nitrate is relatively inexpensive to produce, has a 100% bioavailable nitrogen content and is highly soluble in water making it one of the most widely used fertilizers today [6]. However, it also has an established history of being used as an industrial explosive, most significantly in Ammonium Nitrate Fuel Oil (ANFO) which makes up over 80% of explosive use in the US [6]. Although pure ammonium nitrate is not flammable or
Preimplantation genetic diagnosis (PGD) is a form of genetic testing. It is similar to the screening of abnormal chromosome count only used to test for genetic diseases. The fertility institutes have used this to take gender selection to the next level. Stating that this has a greater than 99,9% success rate.
In GATTACA, Preimplantation Genetic Diagnosis is always the answer. Preimplantation Genetic Diagnosis is a procedure used to identify defects within embryos creates through in vitro fertilization. The procedure is as followed; First, a few cells are extracted from the embryo. Next, the cells are evaluated to identify any genetic defects and where they came from. After the embryos have been examined the embryos without any defects will be placed inside the mother’s uterus. Additional embryo’s free of genetic faults can be frozen for future use. The embryos with flaws will be destroyed. There are many reasons I am not a fan of this procedure. The children with faults are not loved as much as “perfect” children. Instead of being born with a defect and dealing with it they are destroyed. Killed. Every child should be loved. Whether the child has a genetic imperfection like Down Syndrome or is a genius they should be treated equally. They should be loved. It upsets me that
To increase implantation and live birth rates, Ovation Fertility turns to our Las Vegas genetics lab for PGS using next generation sequencing.
October 2001 - Fertility experts announce they will begin to offer PGD for use in sex selection to clients
Mosaic Trisomy 21 happens when an egg or sperm come in with an extra copy of chromosome 21, then,
In the United States, an estimated 2.3 million couples are considered infertile [Wekesser, 1996]. This creates a large need for infertility specialists and clinics specializing in fertility treatments. With the quickly advancing field of rep roductive services and the quest for creating better, healthier babies, a new service called Preimplantation Genetic Diagnosis (PGD) is being offered in conjunction with In vitro fertilization.
Trisomy 21, also known as nondisjunction, means that there is an extra copy of chromosome 21 in the cell and is the most common. Translocation occurs when there are two 21 chromosomes plus an extra piece of chromosome 21 that had attached itself to another chromosome during the division process. Those who have mosaic down syndrome contain an extra chromosome 21 in only some of their cells while others are unaffected. People with mosaic down syndrome tend to have milder physical features and intellectual abilities than those who have trisomy 21 and translocation down syndrome. According to Mark Selikowitz, maternal age is a significant factor in causing trisomy 21. When females are born, all the eggs that a woman will produce are already present. The eggs wait years, some longer than others to be released and it is during the wait period (some 20-40 years) that it is believed errors can occur. On the contrary, man’s sperm does not remain standing therefore less probability for error. Additionally, people with a family history of down syndrome and people who carry the genetic translocation are factors to consider whether the child would be at