Osteoporosis Disease

Osteoporosis is a disorder of bones that affects bones making them low in bone mass fragile and will lead to bone fracture. Bone fracture will easily occur as this disease cause the matrix inside the bone become weak and brittle.Bones can become so brittle due to activities such as coughing can cause fractures.According to Macgill (2015) the origin of the word osteoporosis explain the condition of ‘osteo’ is for bone and ‘porosis’ means porous that resulting in weakness. At this condition, the bone tissue is mineralized normally, but the production is not enough to preserve the normal skeletal architecture. 80% of women and 20% men of 28 million American are affected with the osteoporosis. Approximately, women with the age of 50 will develop osteoporosis. Thin bones are the cause of 1.5 million fractures a year. As in Malaysia, the statistic shows that osteoporosis related to fractured is the common health problem especially in elderly..

Osteoporosis is a progressive bone disease that is characterized by structural deterioration of bone tissue and reduced bone mineral density(BMD). Consequences include increased pain, increased risk of fracture, loss of mobility, and death (Osteoporosis Canada 2014).

Osteoporosis is a treatable disease, but not a curable one. There are different types of treatment for osteoporosis. Some of the medications that can be taken for treatment of osteoporosis are estrogen, bisphosphonates, calcitionin, raloxifene, parathyroid hormone, and testosterone replacement (UCSF Medical Center, 2010). Some of the more common names for bisphosphonates are Fosamax, Actonel, Boniva, and Reclast (Mayo Clinic, 2009). These treatments are taken orally once a week or once a month. In addition to the medications, there is also the treatment of exercise and diet. With a diet high in calcium, stopping unhealthy habits, like smoking and drinking, and regular exercise can reduce the likelihood of bone fractures in people with osteoporosis (The New York Times, 2010). In Ms. Duckworth’s incident, it would be recommended that she increase the amount of calcium in her diet and exercise, and depending on the severity of the osteoporosis, medication.

Osteoporosis is when bones become weak or brittle, and have reduced mass. The bones in the human body are constantly renewing themselves, meaning, the old bone is replaced by new bone and then broken down. At a young age, the body makes new bone at a faster rate than it tears down old bone resulting in an increase of bone mass. However, at a older age, the body stops producing new bone and has to rely on the bone mass that was built up at a younger age.

Osteoporosis is a detrimental bone condition, the tissue in the bones deteriorate and thus the bones become progressively brittle which presents a risk for rupture. Osteoporosis impacts more than 44 million Americans and is linked to a suggested 2 million bone fractures each year. According to the National Osteoporosis Foundation, the amount of fissures due to osteoporosis may escalate above 3 million by the year 2025. Osteoporosis is typically undetected and advances with slight warning signs until a fissure ensues. Effects of osteoporosis encompass height reduction and a curved upper back, anyone can have osteoporosis, however it is prevalent in elderly women and many may break a bone due to this condition. Recovery and prevention are vital in combating osteoporosis, though it may never be eradicated one can take measures to stabilize bone density and gain strength.

The condition of osteoporosis is when the bone tissue of a human being weakens over time, which makes the bones thinner and more porous than a healthy bone. While the bones is getting thinner it is also becoming weaker that will lead to a reduced ability for the bone to endure the weight. The more it increases to get thinner it also sets a person to a high risk of a fracture resulting from falls and they are worst in the wrist, hip and the vertebrae. 2.

To understand osteoporosis, it is important to learn about the bone. Bone is a living, growing tissue that is formed by specialized cell. It provides structure and support, protect the organs and store 99% of the body's calcium; It needs exercise to gain strength. It is made up mostly of collagen, a protein that provides a soft framework, and calcium phosphate, a mineral that adds strength and hardens the framework. The combination of both collagen and calcium phosphate makes the bone both flexible and strong.

According to Elaine N. Marieb & Katja Hoehn (2016). Human Anatomy & Physiology, vol. 10 p192 “Osteoporosis has traditionally been treated with calcium and vitamin D supplements, weight-bearing exercise, and hormone (estrogen) replacement therapy (HPT)”. These are a few things for treatment or prevention. This can be a treatment and a way to prevent osteoporosis from the beginning. Hormone replacement therapy does not reverse the disease but it does help it decrease slower. For example, if the disease is already developed the supplement can help it be slower rather than faster. When this happens then the bone does no become weak faster. Even though this can be an opinion of treatment the topic is debatable because it can come with a lot of other risk factors such as a stroke, a heart attack, or even breast cancer. Many people would take this treatment but others will

These mice had a high bone mass of the vertebrae and long bones and increased cortical thickness. Which is a bone closed to patients with pycnodysostosis. The author decided that mice are not like humans because humans have proteases that can degrade collagen during skeletal development. They decide to try blosozumab and romosozumab. Blosozumab and romosozumab work great together they strongly stimulate bone formation during the first six months of the treatments. At the same time bone resorption is suppressed at the baseline levels then decreases the levels for the remaining time of the treatment. This formula is to help avoid fractures in osteoporosis patients. At this moment this treatment is being considered if measurable targets can be identified for osteoporosis treatment. This treatment raises two new questions. If this target can be defined. Should this target be reached? And how the target should be maintained once it has been reached? Because this would mean patients’ needs repeated courses of anabolic

According to Judith (2010), Osteoporosis is a loss of the reabsorption in the bones by way of calcium, plasma, and phosphate. Estrogen production helps bones metabolism by stimulating osteoblastic activity and limiting osteoclastic effects of the parathyroid hormone. It develops when the new formation of bones fall behind in the reabsorption process (Judith, 2010). In simpler terms, it’s a loss of bone mass due to a metabolic bone disorder affected by the rate of bone resorption advances while the rate of the bone formation reduces. According to Judith (2010), the bones end up losing calcium, phosphates and end up brittle making them prone to fractures and further complications (P . 236).

Osteoporosis is a condition of the bones, which causes weak bones that break easier. According to the FDA, women are five times more likely to develop osteoporosis than men. Currently, there is no cure for osteoporosis but there are lifestyle changes that you can make to slow it down and medications you can take to build stronger, healthier bones. Osteoporosis can run in families. It occurs when a person does not get enough calcium and vitamin D in the diet, as well as not enough exercise. Women who have gone through menopause have a higher chance of having osteoporosis. Anyone can develop osteoporosis but there are some risk factors to keep in mind that increase your chances. Women, people with thin, small frames, a family history of broken bones and/or stooped posture, women who went through menopause before age 45, people who have had eating disorders, and people over age 50 have a higher chance of getting osteoporosis. Also, people who have used certain medicines for extended periods of time, including certain hormones, seizure medications, and certain drugs for asthma, arthritis, or cancer, are at a higher risk. To determine if you have osteoporosis, a test can be done that uses x-rays or sound waves to determine your bone density. Your doctor will know which test would be best for you. To lower your chances of developing osteoporosis, you can make a few lifestyle changes and take medications to help build stronger bones. Be sure you are getting enough calcium. If

A condition that causes bones to become weak. So weak, a fall or bending over, or coughing causes fracture. Osteoporosis related fractures happen in, wrist or spine. Bone is a tissue that needs replacement, breaks down a lot. Occurs when creation of new bone does not keep up with removal of old bone. It affects anyone, but elderly women are a higher risk of getting Osteoporosis. Medicine, balanced diet, exercise prevents bone loss and strengthens weak bones.

Osteoporosis is a condition characterized by a decrease in the density of bone, decreasing its strength and resulting in fragile bones (Shiel). According to The National Osteoporosis Foundation (NOF),the released updated prevalence data estimating that a total of 54 million U.S. adults age 50 and older are affected by osteoporosis and

Osteoporosis is an imbalance between bone loss and bone remodeling. Basically the bone density has become extremely low causing much pain and a higher chance of fractures and or bone breakages. Bone remodeling is responsible for removing mature bone tissue and replacing it with new bone tissue. This disease is more common in older adults, Asians, and Hispanics due to the lack of calcium consumption. Women are often more prone to getting osteoporosis than men because women are born with less bone mass than men. This disease often occurs if full bone mass was not achieved during the bone-building years.

Studies have shown that both estrogen and raloxifene, a Selective Estrogen Receptor Modulator, can prevent the loss of bone mass in postmenopausal women. Alendronate, a bisphosphonate is an alternative to estrogen for bone protection. Calcitonin is another treatment used by women for osteoporosis. This drug has been shown to slow bone breakdown and also may reduce the pain associated with osteoporotic fractures. Treatments under investigation include other bisphosphonates, sodium fluoride, para-thyroid hormone, vitamin D metabolites, and other selective estrogen receptor modulators.