Korsakoff Syndrome Research Paper

BACKGROUND: Ms. Copeland is a 58-year-old left handed white female who was referred to the Hillcrest memory Diagnostic Center by the emergency room physician for evaluation of memory problems and difficulties in functioning including suicidal ideations.

In Jonathon Edwards' homily Sinners in the Hands on an Angry God, he incorporates imagery, hyperbole and personification in order to persuade the audience they will spend eternity in hell if they do not repent.

Erythema multiform: target lesion is the classic presentation, and the 3 skin manifestations are dusky center, inner pale ring, and erythematous outer border. It usually affect age 10-40y/o. Hypersensitivity reaction is most commonly triggered by infection so treat the underlying cause. HSV is most common cause so treat with acyclovir. It is a self limiting condition.

Hutchinson-Gilford Progeria Syndrome (HGPS) is a rare, fatal genetic condition that is characterized by premature aging in children. Its name is derived from the Greek and means “prematurely old.” There are different forms of Progeria, but we will be looking at the classic form that was named after the doctors who first discovered it, Dr. Jonathon Hutchinson in 1886 and Dr. Hastings Gilford in 1897.

She denied having any difficulty with activities of daily living and did not have any problems with memory, concentration, understanding and following directions, completing tasks, or getting along with people. She did not help with house chores. She stated that did not sleep well, took her medication, watched television, played videogames, and “do nothing at home.”

Purpose – The purpose of this paper is to discuss Ekbom Syndrome, also known as primary delusional parasitosis.

Sometimes there are no words. Everyday people discuss a multitude of issues but often the real issue that requires addressing is left as the so called “elephant in the room.” Hemingway expresses through this evasive writing how we are often not strong enough to stand up for what we want and think is right and fall to the desires of others.

Stevens-Johnson Syndrome, a form of Toxic Epidermal Necrolysis, is a rare life-threatening disorder of the skin and mucous membranes which arises from an intense autoimmune sensitivity to mild infections, cancers, and most commonly, medications.

Kinefelter syndrome is a genetic condition that occurs in men as a result of an extra chromosome. The most common symptom is infertility. Humans have 46 chromosomes, which contains all of a person's DNA and genes. Two of which that determines a persons gender. Kinefelter syndrome is the result of one extra X written as XXY. Some of the cells in a male's body have an additional x chromosome. It is found in about 1 out of every 500-1,000 newborn males. The additional sex chromosome results from a random error during the formation of the egg or sperm. Women who have pregnancies after the age of 35 have a slightly increased chance of having a boy with this syndrome. Males who have Kinefelter syndrome may have the following symptoms: small firm

Korsakov's syndrome is a devastating impairment of recent memory that is caused by a thiamine deficiency which can result from alcohol abuse, mal-absorption, hyperemesis or starvation. Furthermore, other causes of Korsakov's syndrome also include heavy metal poisoning, head injury and tumors. A patient suffering from Korsakov's syndrome will most likely have an extensive pathology in the bilateral hippocampus and will actively exhibit confabulation. Confabulation occurs when a patient creates pseudo-memories about what happened during a forgotten episode. Also, during confabulation the patient's recall of the events of the past seem more imaginative than logical. Fortunately, although the patient may exemplify confabulation there

Thiamine is an essential vitamin needed by all cells in the body. When the body lacks thiamine for an extended period of time, many problems arise, mainly in the brain and heart. Alcoholism and malnourishment are two of the leading causes of thiamine deficiency. Although fairly rare, Wernicke-Korsakoff syndrome (WKS) can be a severe consequence of thiamine shortage. WKS is a neurodegenerative disease that affects the brain and disrupts the neuronal signaling. Not only does it make daily life very difficult, it can become life-threatening and cause permanent damage. The lack of thiamine interrupts many biochemical pathways in the body, including the pentose phosphate pathway, glycolysis, and the Citric Acid cycle. Disrupting these pathways causes WKS to present along with multiple other complications.

Wernicke-Korsakoff syndrome is a disease that can cause life-threatening brain damage and mental health issues. The primary cause for the disease is a deficiency of vitamin B1. Most sufferers who contract and recover from the syndrome suffer permanent brain damage. Alcoholism is the predominate – but no only - catalyst for the sickness. Physicians identify most Wernicke-Korsakoff during alcoholism treatment. The disease’s 20 percent mortality rate poses a serious health threat. To date, there is no plausible vaccine for the illness.

The XXY syndrome, most commonly known as Klinefelter syndrome (KS), only affects males of all ages. This syndrome occurs when there is a random genetic error after conception and is not curable, however treatment can help.All females have XX chromosome and all males have XY chromosomes. Unlike the normal XY type that all males have, males affected have an additional X chromosome which results into many symptoms such as impaired spermatogenesis, low testosterone, and male hypogonadism. Since Klinefelter syndrome is related to the sex chromosomes of males, it is a sex link trait.

After this episode a professor convinced her to go to the hospital and reluctantly she complied. This hospital did not take kindly to her psychosis and restrained her numerous times with straps. She had never been treated this way before and was confused and frightened. She later said for a hospital for the mentally ill it had been a brutal experience (157). She then was moved to a different hospital, memorial Unit 10 (MU10) where she was first diagnosed with “Schizophrenia with acute exacerbation” (167). Though she had finally gotten a diagnosis for her broken brain it seemed more like a death sentence than a diagnosis. She continued on with life in depression, psychosis, and denial.

Resident Evil, Andromeda, The Walking Dead, Guardians of the Galaxy, for people everywhere these names ring a bell, but what do these names share in common? They are all popular movies-shows-books titles, centered on genetically engineered humans, that are part of a much larger obsession with genetic modification. Take a stroll into the nearest Barnes and Nobles and in less than an hour one could procure enough books about genetically engineered humans to last their lifetime; that is if science doesn’t allow them to extend their life span another 50 years or so first. What’s with this obsession to create a superhuman, or to be able to choose our capabilities or the looks and smarts of the next generation? This acute fascination is precisely why I believe that alteration of the human genome should be approached with equanimity, not impulsivity. As of yet, we do not have the full information we need to be able to confidently progress forward the process of genetic alteration in humans. While researchers in the medical and science fields are finding themselves caught in the middle of a highly contentious ethical debate, movie makers and writers alike are lining their pockets undermining the possibilities that are teetering on the precipice of our fingertips. To approach this situation we have to be able to sort out what’s fact from what’s fiction. Currently, the rate of success is far too low