Risk Factors Scientists have found a number of risk factors that may influence the probability of someone getting Hodgkin’s disease, but it is still not clear how these factors increase the risk (4). For example, some researchers think that infections with the Epstein-Barr virus may sometimes cause damage to the deoxyribonucleic acid (DNA) in the B lymphocytes, which leads to the creation of Reed-Sternberg cells (4). DNA is the set of instructions sent to the genes that dictates cell functions. Some genes are responsible for controlling when cells grow, divide, and die (4). Genes that assist the cells ability to grow, divide, and stay alive are known as oncogenes (4). Genes that slow down cell division or cause cells to die at the proper …show more content…
The risk is also much higher for an identical twin of someone currently experiencing Hodgkin’s Lymphoma (5). However, a family link is still uncommon--many patients living with Hodgkin’s Lymphoma do not have a family history of it (5). It is still uncertain as to why family relation might increase risk of obtaining this disease (5). It is speculated that family members tend to have similar childhood exposures to certain infections, such as the Epstein-Barr virus, because they share inherited gene changes that make them more likely to get Hodgkin’s Lymphoma, or some combination of these factors …show more content…
The lump does not typically hurt, but the area may become tender after consuming alcohol (6). The lump could grow larger over time and new lumps may appear within the same vicinity, or even different parts of the body (6). Hodgkin’s Lymphoma is not the only cause of lymph node swelling. Most enlarged lymph nodes are caused by an infection, these are referred to as reactive or hyperplastic nodes (6). This type of swelling is typically painful to touch and will return to normal size within a few weeks after the infection is gone
The name often refers to just the cancerous ones rather than all such tumors. Symptoms may include enlarged lymph nodes, fever, drenching sweat, weight loss, itching, and feeling tired. The enlarged lymph nodes are usually painless. The sweats are most common at night.
The most common causes of swollen lymph nodes is infection and will normally disappear within a few days. In rarer cases it can be a sign of cancer (Magee and Schneider, 2006).
Non-Hodgkin lymphoma is a type of lymphoma, which is universal term for tumors that develop in the lymphatic system. It is also called non-Hodgkin's lymphoma. Non-Hodgkin represents for about 90% of all lymphomas, and the remaining 10% are indicating to as Hodgkin lymphoma. Non-Hodgkin lymphomas have an extensive variety of histological appearances and clinical components, which can make diagnosis hard. Lymphomas are not uncommon, and most doctors, independent of their and expertise, will presumably have gone over a patient with
Our genes regulate cell growth and cancer occurs due to abnormal changes in these genes. Genes are in each cell's nucleus and control the cells growth in relation to our genetic make up. The cells grow and replace themselves in a natural
An event that marked my transition to adulthood would probably be when my cousin died a couple months ago she was 17 and she had no Hodgkin's lymphoma. A type of cancer that is somewhat like leukemia. NonHodgkin's Lymphoma is a type of cancer that begins in the lymphatic system. In NonHodgkin’s lymphoma, tumors develop from white blood cells. Your body's lymphatic system is part of your immune system, which protects you against infection and disease. When she died it affected me greatly and I didn't understand why at first because I didn't really know her. I didn't even know her favorite color, she was my cousin I didn’t even get time to ask her what her favorite color was. She was the same age as me when she died, and that is when I begin
Lymphomas are one kind of malignant tumor and they often start in locations such as the lymph nodes. Lymphoma is the third fastest growing cancer in the world and affects people of all ages. Lymphoma is a common cancer that has specific symptoms and treatments.
According to Cancer Treatment Centers of America some common symptoms of NHL include fever, night sweats, chills, persistent fatigue, lethargy, loss of appetite, nausea, vomiting, unexplained weight loss, abdominal pain or swelling, skin rash, itchy skin (pruritus), coughing, shortness of breath, headache, difficulty moving, pain in the chest, abdomen or bones for no reason, and swelling in the lymph nodes in the neck, underarms, or groin. (Non-Hodgkin) Certain symptoms of lymphomas are similar to those of an infection; consequently, doctors usually test for infection and then order a biopsy of the enlarged lymph node or other affected area when they believe that the swelling is not caused by infection. (Test) There are many different types of biopsies. The two most common types of biopsies are excisional and incisional biopsies. An excisional biopsy is when a doctor removes the entire lymph node. An incisional biopsy is when a small part of a larger tumor or node is removed.
Tumour suppressor genes: In health this family of genes usually act as a counter balance for oncogenesis. It is thought that they may be responsible for repairing gene damage in cells, or are growth inhibitor genes. In Hodgkin’s disease, there are often evidences of mutation in tumour suppressor genes as well as other genes.
Endosymbiont genomes follow a general trend of reduction and increase in stability over time. Mitochondrial Genomes follow this same trend appearing to be an aggregation of several smaller genomes which have reached a point of stability. The bacterial endosymbiont Hodgkinia, found in various forms throughout cicada populations, have been observed to undergo extreme genome instability possibly as a result of the extended 13 to 17-year cicada life cycles.
Swollen lymph nodes are a symptom of impacted wisdom teeth, or at least that is what I was told that was causing the knots behind my ear when I was at the dentist. My teeth were shoving their way into my jawbone, causing the Smile Center to send me to Ruleville with an aching pain.
The topic I decided to do my paper on is Hodgkin’s Lymphoma in this paper I will talk about what Hodgkin’s Lymphoma is different kinds of Hodgkin’s Lymphoma, treatment, statistics, and the survival rate. I will also talk about the staging system, risk factors, how it can be found early, if it can be prevented, what causes the disease, symptoms and signs of the disease, and how it is diagnosed and treated.
The 27 year old female patient was promptly investigated and the diagnosis of Hodgkin’s lymphoma was timely. Based on the complete work up, diagnosis and results, the patient’s final diagnosis was that she was affected by classical Hodgkin’s lymphoma, nodular sclerosis, in stage IV-A (advanced stage), which is based on the Ann Arbor classification which is used for the staging of Hodgkin’s lymphoma. In conclusion, this case report is subjective but symbolic because it stresses the importance of early diagnosis, staging and risk assessment of Hodgkin’s disease in primary care settings and internal medicine in order to improve the survival rate of patients. (Bolognesi, M. Bolognesi, D and Pasini, G, 2015)
The type of lymphoma and where it is in the body will determine the types of symptoms one may experience. Sometimes it may not cause any symptoms until the tumor grows quite large (Cancer.org). Warning signs that you may have Lymphoma include; swollen glands (lymph nodes), often in the neck, armpit or groin, persistent cough, shortness of breath, fever, night sweats, stomach pain, fatigue (extreme tiredness), weight loss, itching, swollen abdomen, feeling full after only a small amount of food, chest pain or pressure (Cancer.org) Many of these symptoms can be indications and warnings of other illnesses. Be sure to see your doctor if you experience any of these symptoms to rule out any other diseases as well as
Heredity also plays a role in the development of cancer. If a person’s relatives have a history of cancer, then that person has a higher risk of developing cancer. Genetic variations, particularly those influencing how the body responds to carcinogens, may create a greater vulnerability to cancer.
In a typical cell, the progress of organised systems manage the pace and timing of cell development, division and death. Be that as it may, now and again, this cell cycle can go amiss. External components, for example, cancer-causing agents, toxins and UV beams, can harm the cells ' DNA, setting off the loss of the control system that direct when and how quick certain cells partition and die. Heredity can likewise have a part in a few varieties of malignancies, especially when joined with these outer triggers.