Genetic Disease: Cystic Fibrosis

Cystic Fibrosis, also known as CF, is one of the most common life-threatening genetic disorders found in people. Discovered in 1938 by Dr. Dorothy Hansine Andersen, Cystic Fibrosis severely affects two parts of the human body, including the respiratory system and the digestive system. Cystic Fibrosis causes the mucus glands to secrete very thick and sticky mucus. This mucus then clogs the tiny air passages and traps bacteria in the lungs. The thick mucus also stops the release of digestive enzymes in the pancreas from reaching the small intestine. According to Cystic Fibrosis Queensland (2015) more than one million Australians carry the Cystic Fibrosis Gene, with one in every 25 people, often not realising they are carrying the deadly gene.

A widely accepted Caucasian disease has since changed; as cases of its existence are appearing in the South Asian Population (Orenstein, Rosenstein and Stern, 2000). First discovered in 1989, Cystic Fibrosis (CF) is a genetically predetermined condition, its presences is lifelong and highly complex, which is why many CF sufferers and families develop various mechanisms in order to adapt to the condition (Tippingemail, Scholes, Cox, 2010). Cystic Fibrosis causes the body to develop thick, sticky mucus which clogs the lungs and affects other organs in the body, mainly the pancreas. The layer of mucus if untreated develops in to a chronic infection which can be detrimental. The pancreas of a CF patient is most vulnerable, once the mucus has

Cystic Fibrosis is a genetic disease which is progressive and limits breathing ability. The lungs and other organs are affected by a thick buildup of mucus. This mucus traps bacteria which leads lung damage, infections, and respiratory failure. The digestive enzymes being released is prevented, affecting the breakdown of food and nutrients being absorbed. ?More than 30,000 children and adults in the United States have Cystic Fibrosis. 70,000 people worldwide.? (Diagnosed With Cystic Fibrosis, Cystic Fibrosis Foundation) Someone who has Cystic Fibrosis have a defective gene from each parent which produces faulty protein. The CFTR gene is the gene that is mutated causing this. The channel that transports chloride in and out of cells is created by instructions that are created by CFTR gene. The regulation of chloride ions and water are prevented creating the thick mucus formed on the passageways of lungs, pancreas, and other organs. Cystic Fibrosis doesn?t cause learning problems are mobility of the person. Babies with this still develop and grow up normally. The average life expectancy is close to 40 years, and has been increasing in the last fifty years thanks to improved care. ?Chronic coughing, recurring chest colds, wheezing, shortness of breath, frequent sinus infections, and allergies that last all year, are the most common symptoms of Cystic Fibrosis.? (Cystic Fibrosis Symptoms) Since this disease is progressive

Nearly 1 in every 30 Americans are a carrier of the recessive gene that leads to CF (About Cystic Fibrosis, n.d.). Although CF is a life-threatening condition, through the advancement of treatments and care, there has been a steady increase in life expectancy and improvement in the quality of life. The current mean age of survival is now 40. Although that does not seem very high, sixty years ago, a child diagnosed with CF did not survive childhood (About Cystic Fibrosis, n.d.). CF is a complex disease, where the types and severity of symptoms can differ widely from person to person. Symptoms may include fatigue, salty-tasting skin, persistent cough with phlegm, wheezing and shortness of breath, lung infections, and poor growth and weight loss (Cystic Fibrosis Symptoms, Causes & Risk Factors, 2018). Many different factors, such as the age of diagnosis, can affect an individual's health and the course of the

Cystic Fibrosis is one of the most common and fatal genetic diseases in the United States. Cystic Fibrosis is a disease that causes the body to produce a thick, sticky mucus that clogs the lungs. This can lead to infection and blocks in the pancreas, which stops digestive enzymes from reaching the intestine where they are required in order to digest(“Learning About Cystic Fibrosis,” 2013). Cystic Fibrosis can go undiagnosed for a long period of time. For example, Mackenzie Dondanville 11 years old, four years ago, who had been coughing a lot for the previous year and a half. Due to her being physically athletic while competing in soccer, her pediatrician thought her cough and shortness of breath was due to exercise-induced asthma. It wasn't until Mackenzie's prescribed inhaler isn't working, that they realized something more was going on (“Mackenzies Story,”2018).

The Cystic Fibrosis Foundation provides support to help improve the lives of people who live with the disease. The foundation’s main goal is to find a cure to Cystic Fibrosis is an inherited disease caused by changed in a gene on chromosome seven. It is described as a buildup of mucus in the lungs and organs. The mucus in the lungs clogs the airways and bacteria grows, gets blocked in and eventually leads to infections that causes lung damage. After lung damage has occurred, respiratory failure then happens.

Kaneshiro describes cystic Fibrosis as a system wide disease process that affects the mucous production of organs from the time of birth, most commonly affecting the lungs and intestines (2014). He goes on to say that this is a hereditary disease that is most commonly found in the first 2 years of a child’s life and the symptoms start out as mild and can be easily overlooked, which accounts for the late diagnosis even though the disease started at birth (2014). The most common early life symptoms include a lack of stools in the first couple of days after birth and salty tasting skin though as the child ages there is a significant lack of developmental growth and lack of weight gain along with frequent respiratory infections and constipation (Kaneshiro, 2014). The life expectancy of a child with CF currently is at around 37 years old when that child receives extensive early treatment for the side effects of CF, though there is no cure at this time, though the treatments are getting more effective every year (Kaneshiro, 2014).

What is Cystic Fibrosis? Cystic Fibrosis is a disease inherited past down from many generations. Another name for cystic fibrosis is called clubbing there are many other name terminologies for cystic fibrosis. The name of the disease originates from the tough tissue, which scars inside the pancreas, first documented in the 1930’s. The pancreas is one the major organ attacked by a faulty chromosome no.7 where cystic fibrosis has been found. A cystic fibrosis patient can have the recessive gene and both of his or her parents can carry the gene but not affected by the gene. The disease attacks the external glands, which includes (lungs, perspiration glands, gastrointestinal system, and a man’s masculinity). Cystic fibrosis can cause several different

Cystic Fibrosis (CF or CFTR) is a life threatening disease that causes the buildup of thick and sticky mucus in many organs and body systems, and the mutated genes are passed down from parent to child. It affects about 30,000 people in the US, about 5% of the U.S Population carries the disease, but they do not have it. CF is most commonly present in Caucasians and some Hispanic. CF is less common in African Americans and Asians. Although cystic fibrosis is rare in most race, if it is inherited, it can life threatening when it isn’t treated in the early stages.

Can you imagine struggling and gasping for air for an everyday normal? It all ended for her in the year of 1988. More than 30,000 Americans are diagnosed with it a year. Leslie Adelynn Lacey, a young girl from the small town of Kosciusko, Mississippi, was diagnosed with cystic fibrosis when she was only six months old. Cystic Fibrosis, (CF) is an inherited life-threatening disorder that damages the lungs and digestive system. Mucus builds up in the lungs and blocks the person’s airway, causing this person to have trouble breathing regularly. CF is a genetic disease, meaning that a person does not catch it, it is passed down through DNA. Cystic Fibrosis last with a person his or her entire life time. It occurs throughout the world in every race and ethnicity. There is absolutely no way to prevent a person from contracting CF. Lifespan expectancy is usually 21 for a patient diagnosed. Even though there is no cure for cystic fibrosis, the advancements in learning about the condition, genetics and therapy are a working progress throughout medical experts, and maybe, one day there will be a cure.

Cystic Fibrosis is a recessive disorder that is a life threatening disease that causes persistent lung infections and progressively limits the ability to breath. Unfortunately, there is no cure for this genetic disorder, but Airway Clearance, Inhaled Medicines, and Pancreatic enzyme supplements can increase the person’s lifespan incredibly. There are about 70,000 people worldwide with this disease. Approximately 1,000 new cases of cystic fibrosis are diagnosed each year. The average human with cystic fibrosis lives to about 30 if they take their medicine.

Imagine drowning, lungs filling with water that swallows the air and suffocates those caught in it. Now, imagine drowning in a hospital bed surrounded by doctors and family members who can only stand by and watch the inevitable. This is the fate of a person with Cystic Fibrosis. Cystic Fibrosis is a disease that forces a person to drown in mucus that fills their lungs while it wreaks havoc on the body. This chronic disease causes devastating health problems, has no cure, and forces patients to endure painful temporary treatments. Taking daily medications, maintaining a social life, and staying moderately healthy are a constant struggle for people with Cystic Fibrosis.

Cystic Fibrosis is a disorder where the exocrine glands secrete abnormally thick mucus, leading to obstruction of the pancreas and chronic infections of the lungs, which usually cause death in childhood or early adulthood. Some mildly affected patients may survive longer. Doctors can diagnose the disease by testing the patients perspiration because people with Cystic Fibrosis have high amounts of salt in their perspiration. Those with respiratory infections are treated with antibiotics, with aerosols that relieve constriction of the airways and liquefy the thick mucus, and by physical therapy to help patients cough up the obstructing secretions. Patients with pancreatic insufficiency can take pancreatic enzymes with meals.

introduction: Cystic Fibrosis is a genetic condition that causes the internal organs (the lungs and digestive system) to become clogged with thick sticky mucus that results in chronic infections and inflammation of the lung.

Cystic Fibrosis, a very serious inherited genetic disease, is also known as CF and sixty-five roses. This disease affects one in every 3,000 live births. It may first appear in a newborn, but can appear all the way up until a young adult. However, ten percent of most cases are apparent at birth. CF affects the lungs and causes a build-up of abnormally thick mucus which leads to chest infections, and CF also affects the reproductive system. Doctors do not know what causes the mucus to thicken. CF’s infections usually lead to death in childhood and early adulthood. Most people infected with CF had a life span into their teens long ago. Now, due to advanced technology, the life span is in the fifties or older.