Campylobacter species are one of the most prevalent and widespread bacterial enteric pathogens in both industrialized and developing countries [1]. It account for most cases of human gastrointestinal infections worldwide, causing 400-500 million cases of diarrhea each year [2]. In the European Union (EU) in 2008, 190,566 cases of campylobacteriosis was confirmed [3], while in the United States (USA), an estimated 2.4 million incidents occur each year [4]. A total of 220,209 Campylobacter cases were reported and confirmed by the EU in humans in 2011, and 212,064 established cases in 2010 [5]. In developing countries, Campylobacter-related gastroenteritis rates are most common amongst children less than five years old [6]. Campylobacter infection is primarily a zoonotic disease as it is a commensal of food animals, particularly poultry, which serves as the main reservoir for human infection [7]. Other sources of transmission, include water, milk, and food animal meat products [8]. The disease characteristics vary from watery, non-bloody, non-inflammatory diarrhea to a severe inflammatory diarrhea followed by abdominal pain and fever [9]. Amongst …show more content…
However, the emergence of antibiotic resistant strains poses a challenge in the management of Campylobacter infections. Isolates of C. jejuni and C. coli with resistance to various antimicrobial agents have been reported in both developed and developing countries [12]. There is a dearth of surveillance systems/data? on clinical Campylobacter in South Africa, particularly in the private healthcare environment. We therefore investigated the prevalence of resistance against ciprofloxacin and erythromycin, as well as against newer antibiotics in these classes, viz., gatifloxacin, azithromycin and tetracycline in clinical Campylobacter isolates from a private pathology laboratory in South
According to a trial trying to determine bacterial resistance within the Enterobacteriaceae family “E. cloacae has been proven resistance to ampicillin, amoxicillin-clavulanic acid, first-generation cephalosporins, cephalothin, cefoxitin, broad-spectrum cephalosporins, as well as third generation cephalosporins.”1 The trial also stated that “this vast resistance is due to the bacteria’s
Helicobacter pylori is structurally small, gram negative rods which is microaerophilic in nature and has capability of colonizing regularly in human stomach (Strausbaugh et al., 2002). Due to such colonizing capability, it is regarded as one of the most common bacterial pathogen present in almost 50% of the world’s population (Zhao et al., 2014) and the reason behind such well adaptation or enduring of H.pylori in the Human’s stomach is due to the combined effects of several factors that addresses different challenges or obstacles presented by the nasty environment inside the stomach (Montecucco and Rappuoli, 2001). Helicobacter pylori produce the urease that neutralize the gastric acid or shows the buffering effect around the surroundings within the stomach. Moreover, it has a capacity of crossing the thick mucus lining of the stomach easily and binding itself to the antigen known as Lewis antigen that are basically present in gastric cells and whose function is to secrete different factors associated with stimulating and attracting the inflammatory cells and Toxin VacA that performs the multiple functions and such activities of H.pylori is possible due to its helicoidal shape the mode of action of flagella present. Mainly, the presence of the cag pathogenicity island (Cag-PAI) which is a 40-kb DNA insertion elements containing 32 genes and encoding a type IV secretion system helps in the optimal fitness of the bacteria in the stomach and appearance of pathogenic traits.
Helicobacter pylori are a species of epsilon proteobacteria which colonizes the harsh environment of the human stomach. Its name refers to both its spiral shape (Helicobacter) and the area of the lower stomach which it habitually colonizes: the gateway (pylorus) between the stomach and small intestine (Meyers, 2007). This bacterium is thought to be present within up to 50% of the human population and has been linked to the development of a number of different medical conditions (Chalmers et al. 2004). This report will provide
According to various scientists, the routine use of antibiotics on the farm have promoted drug-resistant superbugs in the factories. An evidence was from Food and Drug Administration (FDA) through the approval of flouroquinolones, an antibiotic class with ciprofloxacin, which has been in the production of poultry since the year 1995 (FDA, 06). In 1999, ciprofloxacin-resistant Camplobacter,
Campylobacter -like organisms can produce an enterocolitis/proctocolitis syndrome in homosexual males, who are at increased risk for Helicobacter cinaedi and Helicobacter fennelliae infections. C jejuni infections may also produce serious bacteremic conditions in individuals with AIDS. Most reported bacteremias have been due to Campylobacter fetus fetus infection. Campylobacter lari, which is found in healthy seagulls, has also been reported to produce mild recurrent diarrhea in children.Campylobacter upsaliensis may cause diarrhea or bacteremia, while Campylobacter
After receiving the test results, the samples confirmed to bacteria that was in the water. The two bacteria’s where Coliform Bacteria and E.Coli. Coliform bacteria is present in the feces of all warm-blooded animals and humans. The three water samples for total coliform bacteria were 57,000 CFUs, 43,000 CFUs and 45,000 CFUs. The team of scientist was in surprise due to the high contamination level of the Coliform
According to Aziz (2013), “C difficile is a spore-forming, Gram-positive anaerobic bacillus that is the most common cause of diarrhea in hospitalized patients” (p.1). C diff. infection occur when a patient is being treated with an anti-biotic for a particular disease and this anti-biotic depletes the number of good bacteria to an extent that it creates an environment suitable for an opportunist pathogen like a fungi or bacteria to take over and infect the patient with a different type of illness. In hospitalized patients, especially those who are taking a lot of antibiotics, normal bacteria in their guts can be killed and in this case leaving C-diff to multiply and cause an infection. Diarrhea and stomach cramps are one of the symptoms of C.diff infection. I some cases serious inflammation of the colon can also occur. The infection can be acute or chronic which means that the infection can last 2-3weeks or more. Isolating infected patients helps to reduce the spread of this infection to other patients in the hospital. Health care workers should also use the appropriate protective equipment to assess the isolation rooms and have these patients not
Gastrointestinal diseases are pervasive problem that is caused by ingestion of contaminated foods or water in which an extensive etiological agents known as enteric pathogen are present, [1]. Salmonella is one of the most opportunistic gram negative, facultative anaerobic food borne pathogens that represent a major health problem and a substantial cause of food poisoning[2]. Salmonellosis caused by Salmonella enterica serovar Typhimurium (S. Typhimurium) stance as the second most prevalent cause of acute gastroenteritis that affecting one million illnesses in the United States, with 19,000 hospitalizations and 380 deaths[3]. Infection begins with the ingestion of contaminated food or water then characterized by attachment of the bacteria by fimbriae or pili to cells lining the
Neonatal calf diarrhea remains an important cause of morbidity and mortality in young calves that causes substantial economic losses (Constable, 2004). Diarrhea in neonatal calves is a syndrome of great etiological complexity, in addition to the influence of various environmental, managemental, nutritional and physiological factors, numerous infectious agents are capable of causing neonatal calf diarrhea (Schumann et al., 1990). Multiple enteric pathogens have been recovered from diarrheic calves, their relative prevalence varies geographically but Escherichia coli, Rotavirus, and Coronavirus, C. perfringens, Salmonella spp. and Cryptosporidium spp. are recognized as the most common infectious agents in most areas (Garcia et al., 2000; Snodgrass et al., 1986).
Fine Line Family K-9 has raised many top Dogs when it comes to Family Protection. You need a Dog that is able to protect you, play with the Kids and adapt to any mode you need them to perform with ease. Most people do not understand how much a Family Protection Dog can bring completeness to your home. Here are some of the facts that would interest you:
faecalis and E. faecium. However, even though tetracycline exhibit clinically significant anti-enterococcal activity, it is generally considered a second-line agent and is seldom used for enterococci treatment nowadays, so these results may not be alarming. Nonetheless, this finding, as well as increasing rifampin resistance in E. faecium urine, although non-significant, should be taken seriously and preventive measures should be taken. More concerning is the emergence of linezolid resistance in both E. faecalis and E. faecium, which remains a crucial therapy for VRE faecium, providing additional evidence of a growing public health crisis. Linezolid resistance in enterococci, although still relatively less common, has been linked with increasing linezolid use previously.18 Our findings could also be related to the involvement of antibiotic selective pressure on changing enterococci resistance, supporting a cautious use of these antibiotics and reinforcing the need for better infection control strategies and alternative therapies to treat enterococci infections. Our findings may explain the linezolid resistance of <30.2% for E. faecalis urine isolates observed in a previous
I selected a presentation on Antimicrobial Resistance given by Dame Sally Davies, England’s Chief Medical Officer, for the Royal Institution of Great Britain. This review will focus on the first five minutes of the lecture (https://www.youtube.com/watch?v=2H_Ox1vVnTc, 0:10-5:35).
Sickness and disease has always been a concern within our society but in recent years treatment and prevention has become more difficult. Resources are being spent on trying to develop vaccinations and antibiotics for wildly diverse and common infections, and none more than the prevalence of the microbial pathogen Salmonella. Our understanding of this pathogen has only reached infancy stage, leaving a high demand for further understanding of the organism, pathways of infection, and its potential effect on our society.
While taking the personal finance course this past spring, I learned many valuable lessons that will greatly assist me throughout my life. One lesson I learned is the importance of paying yourself first. To put this into action, I will save money in an emergency fund to have enough money to live comfortably for 3 to 6 months, in case of emergency. Furthermore, this course has taught me the importance of budgeting. Using budgeting, I will make a plan for my money, so I can avoid over drafting and bouncing checks. Another lesson personal finance taught me is to pay all bills and loans on time to develop a good FICO credit score, which is what companies use to evaluate the risk of loaning to an individual. Knowing this information will help me
The nature of the learner is the most important aspect in the planning process for distance learning. It is one of the elements of the Unit Model Topic (UMT) approach. This design process allows the instructor to consider elements such as the content, the nature of the learner, the process by which the learning will take place (methodology) and the means for assessing the learning experience (Simonson, p. 128). Dr. George Piskurich is in agreement with this point when he discusses the key elements in planning an online course is “to know exactly what the learners need to learn and to know what learners can use.” (Laureate Education, n.d.).