In Accordance to our survey question number 13 asks when should the drug be stopped? There where 78 responders 53 responders (67.95 %) replied tachycardia, 6 responders replied vomiting (7.69%), 12 responders (15.38%) replied feeding intolerance, 8 responders replied jitteriness(10.26%) and the 21 responded other. Moreover, the respondents that replied other had Tachycardia as the highest number thus this accounts for the highest overall respondents which believed that the drug must be stopped if the caffeine cause the heart rate to increase more than 200bpm. 4 respondents said necrotizing entercolitis (NEC) was the primary reason the drug should be stopped. Followed by two respondents that said both tachycardia >200bpm and NEC. …show more content…
A double blind randomized control trial conducted by Mohammed S et all (2015)., aimed to prove that using a higher, than current standard, loading and maintenance doses of caffeine for treatment of apnea of prematurity is well tolerated, may decrease the chance of extubation failure in ventilated patients, and significantly decrease the frequency of apnea. Moreover, the high-dose of caffeine was associated with significant increase in episodes of tachycardia (p < 0.05) without a significant impact on physician decision to withhold caffeine. In addition to that, no increment in the rates of NEC in preterm infants after receiving a loading dose of caffeine citrate of 20 mg/kg per day followed by maintenance doses of 10 mg/kg per day compared to standard-dose regimen. [55]. https://link.springer.com/article/10.1007%2Fs00431-015-2494-8 A retrospective study included 89 patients, illustrated that there was a low incidence of tachycardia attributed to caffeine therapy, with 9 infants experiencing one episode of tachycardia and 2 infants experiencing three episodes (Figure 7). In addition to that, the critical threshold for serious toxicity with caffeine therapy is >50 mg/L. Suzanne J. Francart et all (2013). An article written by Gian Pacifici (2014), revealed that jitterness occurred in an infant with plasma concentration level of 61.7microgram/ml, and toxic effects start to show at levels ranging from
According to the results, the columns of caffeine in figure 1, of this experiment the hypothesis for caffeine is partially accepted. There is an increasing trend in the change of pulsation rates with increasing
Pregnancy and certain contraceptives may bring on jitters, a side effect of caffeine, to the female population. “A two- hundred-pound man who drinks a cup of coffee with a hundred milligrams of caffeine will have a maximum caffeine concentration of one milligram per kilogram of body weight. A hundred- pound woman having the same cup of coffee will reach a caffeine concentration of two milligrams per kilogram of body weight, or twice as high” (Gladwell, 233). I can usually consume two to three cups of coffee before noon, while my wife can only handle one to two before the jitters set in. The metabolism of medications changes with aging; therefore, the older population should monitor caffeine intake. My parents have switched from caffeinated to decaffeinated beverages due to how caffeine affects their body, making them feel jittery after one cup of
If and when caffeine crosses the placental barrier it means the maternal blood levels of caffeine are virtually equal to fetal blood level (Collines, 2007). There are certain enzymes needed for the metabolism of caffeine and these enzymes are absents in fetus (Collines, 2007). Due to the lack of this enzyme, this could lead to malformations in the fetus (Collines, 2007). Previous studies done in rats show high caffeine levels have an effect on blood vessels in the placenta which causes them to contract therefore restricting or diminishing blood flow (Fernandez, 2016). Studies of animal models show caffeine can delay ossification, because missing digits, stillbirth and low birth weight (Fernandez, 2016). (MS & RL, 2001). Caffeine’s chemical formula is C8H10N4O2 (Collines, 2007).
About 80% of American adults consume 200 mg of caffeine a day. “A 12-oz. (tall) coffee from Starbucks will run you about 260 mg, while a 14-oz. Dunkin’ Donuts coffee contains 178 mg.” The daily intake of caffeine differed between products; one should always check the amount before consumption. There are no limits on how many energy drinks a person can purchase, which make it easy to abuse. Especially in younger children the addiction rate outstandingly high. Which may lead to other drug usage in the future and the committal dependence on stronger drugs.
Caffeine has many negative effects on humans, such as increased heart rate (Lane, J.D., 2002), depression (Goldstein, 2008), and addiction to this “drug.” You may be asking yourself, “What is caffeine?” Well, caffeine is actually a stimulant (Barone, Roberts, 2008) that is found in beverages such as tea, coffee, and soft drinks. In fact, caffeine is the highest grossing and most used stimulant in the United States (Barone, Roberts, 2008). It is estimated that 85% of adults living in the United States consume caffeine on a daily basis (Barone, Roberts, 2008). That means for every 100 adults, 85 of them have had a drink that contained caffeine on any given day. One reason caffeine is so widely available compared to other stimulants is
The problem of this research is to determine the effects of the caffeine to the babies and the abuse of the caffeine to the pregnant women. To know the things that the caffeine can do, we need to have a research about it. To know these, the researchers should work out to these following questions:
The metabolism results of study A showed caffeine results (Fig. A) as expected. Pre-caf gave the earliest caffeine reading, followed by dur-caf. Urinary caffeine levels (Fig. B) were well below the International Olympic Committee regulation of 12µg/ml. Plasma analysis showed that blood glucose levels were higher in the pre-caf treatment, possibly due an increase in metabolic rate from the
Apnea of prematurity is a developmental disorder in preterm infants and is one of the most common NICU diagnosis that requires therapeutic intervention. Caffeine citrate is used in the NICU for the treatment of apnea of prematurity (AOP) in infants between 28 and 32 weeks gestational age, and neonates weighing less than 2 kilograms. Usually given for about seven days with the goal of decreasing apneic spells by 50% (lexi). This drug can be given by mouth or IV. It is generally considered a diagnosis of exclusion.
III. “The U.S. Food and Drug Administration (FDA) and the American Medical Association (AMA) have estimated that the average daily caffeine
The daily consumption and reliance on caffeine in the United States is increasing exponentially. Although many studies have demonstrated the negative effects caffeine imposes on the human body and brain development, there has been no notable decrease in society’s caffeine intake. A vast majority of the publicity that caffeine receives is based on the positive indicators that it can reduce the risks of other health factors. Caffeine is a psychostimulant drug that affects not only the human body postnatally but also the fetal brain during development. Consumption of caffeine includes variety of beverages and foods that are ingested daily such as coffee flavored products, tea, chocolate, energy drinks, and soft drinks. Research is being furthered on the negative implications of the consumption of caffeine on fetal brain development. Outcomes after birth may result in characteristics of “low birth weight, intrauterine growth retardation, and miscarriage” (Mioranzza et al., 2014). Research however has focused on the negative effects specifically in the central nervous system, examining the short term and long term effects on brain development. The effects include behavioral and chemical modifications and consequences induced by prenatal exposure of caffeine on the developing fetal brain. Much of the publicity caffeine receives is positive image that promotes its health benefits rather than risks. Despite
Some of the main side effects include Headache, Tremor or Shaking, Chest pain, and many others include death. Around eleven deaths have been blamed for consuming the drink. Young consumers should not consume more than 2 at max within a timespan of twenty-four hours. Around 17 to 20 hospitalizations has been caused by the drink. There has been a discussion between the company and factories to lower caffeine levels by 00.2% but has never happened. Depending on who the human is and the shape he or she is in the caffeine may affect differently to that specific type of person.
This article discusses the affects caffeine has on several aspects of human health. These included toxicity, cardiovascular effects (arrhythmia, heart rate, cholesterol and BP), bone/calcium balance, behavior, and reproductive and developmental effects. It also discussing the affect caffeine intake has on children and reproductive-aged women.
Thesis: Caffeine can have many different effects on the body depending on the amount of consumption.
In some cases, some people may need to avoid or limit caffeine consumption due to a health conditions or individual sensitivity. Certain sensitive groups, such as pregnant women and
is derived from a bean or from tea leaves and can be found in the