Antimicrobial Resistance To Antibiotic Resistance

A Superbug is a bacterium that can live in the human body and has the ability to withstand all forms of antibiotic medication. Superbugs are becoming increasingly significant in modern medicine as they are becoming more and more resistant to antibiotics. Antibiotics were discovered in 1928 by Alexander Fleming (Walsh and McManus, 2000). This resulted in a huge movement forward in medical history and even greatened human life expectancy. Since then antibiotics have been widely used and abused, people began to treat everything with this ‘miracle’ drug. If antibiotics are continually used as bacteria grows exponentially more resistant to them then eventually society will fall back into an era without the readily

Possible solutions for resistance in the future are to find new antibiotics in niches besides soil, such as the marine environment as globalization and deforestation make new soil discoveries harder each day. Educating people about resistance to prevent misuse is important as well because not everybody knows about the growing resistance problem. If people know about the resistance problem, proper use of antibiotics would increase. Antibiotics today are easily accessible without the need of prescription in most cases, leading to the wrong self-diagnosis based on observation instead of actual tests. Creating more regulations to ensure prescriptions and correct diagnosis will help with the misuse of antibiotics. Stopping their use as growth hormones in agriculture will also help because the antibiotics from the plants and animals are able to unnecessarily get into a person’s body, which promotes more antibiotic resistance since the dosages are not consistent. As the antibiotics pass through the livestock and people, they contaminate the water system. The antibiotic resistance today does not necessarily mean the end of antibiotics as long as

The Centers for Disease Control and Prevention (CDC), describes antibiotic resistance is the ability of bacteria or other microbes to resist the effects of antibiotic treatment. () So instead of being destroyed by the medications, the bacteria survives and continues to reproduce, resultant in new communicable diseases that even more difficult to treat.

When antibiotic is used most of the bacteria die but a few bacteria with antibiotic resistance gene survive and reproduce and pass this advantage to their offsprings. This selective pressure exists naturally, however antibiotic misuse can be accused for fastening the spread of the antibiotic resistance gene [Refer to figure 2] (Learn Genetics 2015). Consequently, inappropriate antibiotic intake will lead to a greater chance of superbugs being developed. Antibiotic resistance can be defined as a new ability which a bacterium has developed to stay unattached in the presence of an antibiotic that was previously effective to destroy the bacterium (ABC science 2015). Four key mechanisms that has been identified for bacterial antibiotic resistance can be listed as: producing enzymes that inhibit the functionality of the drug, reducing the effectiveness of the drug by producing targets against which the antibiotic, reducing the permeability of the drug into the bacterium and active export of antibiotics using various pumps (Pogson 2012). All these mechanisms can be developed by any of the bacteria when the corresponding mutated gene of antibacterial resistance is received. The genes code for specific proteins, and variation in the gene leads to alteration of the shape of proteins. This leads to changing the functionality

A current predicament in the field of science is antibiotic resistance against superbugs.Though fighting against superbugs; which can be defined as a strain of bacteria unable to be killed using multiple antibiotics, is now a large problem, in the past it was not. The evolution of resistance in bacteria due to antibiotic abuse and lack of product development has brought upon us once again the fear of a pre-antibiotic era; one where simple, once easily defeated infections could kill. Already, infectious diseases are the 3rd leading cause of death in the US and the 2nd across the entire world, and drug resistant superbugs send 2 million Americans to hospitals every year; killing 23,000 of those people. And any bacterium can quickly and easily become multidrug resistant, the leading cause of this being antibiotic misuse in both humans and animals.( "Clinical Infectious Diseases." The Epidemic of Antibiotic-Resistant Infections: A Call to Action for the Medical Community from the Infectious Diseases Society of America. UCLA Medical School. Web. 27 Mar. 2016.)

The problem is that antibiotics resistance has become a very big problem in todays society. Antibiotics are no longer effective against certain super-bugs such as MRSA.

(Centers for Disease Control and Prevention, 17 April 2015, para. 7). If your doctor has ever given, or will give you antibiotics, the misuse, the wrong dosage, and even the wrongful prescription of antibiotics, such as for a virus, can eventually contribute to making a superbug, again according to the CDC (Centers for Disease Control and Prevention, 1 February 2017, para. 2-5). There are already many instances of superbugs taking people’s lives. For example, just this January 2017, the CDC reported that a Washoe County resident in Reno, Nevada died in late September 2016 because she had an infection from a superbug that could not be cured by every available antibiotic in the United States (Centers for Disease Control and Prevention, 1 August 2017, para. 1-5). Posted on the Infectious Diseases Society of America website in 2007 by her mother was the story of how Rebecca Lohsen, a 17-year-old high school student and swimmer from New Jersey, died from an MRSA infection, an infection resulting from a superbug (Infectious Diseases Society of America, September 2007, para. 1). On that same website, posted by her parents, a 19-year-old college student, Meredith LittleJohn, died to a superbug after spending time in an intensive care unit in a hospital (Infectious Diseases Society of America, n.d., para. 1-3). And the list of those affected goes way on. So as we can see, superbugs are definitely a threatening and real issue that can affect almost anyone.

Antibiotic resistance is when microorganisms, such as bacteria, are able to survive an exposure to antibiotics and these bacteria are now resistant to the effects of these antibiotics. Antibiotic resistance in bacteria has been an issue since antibiotics were discovered. The fact that bacteria can become resistant to our medical treatments such as antibiotics is a natural evolutionary process, but there are certain human contributions that definitely speed up the process. For example, one of the main contributions that will be discussed is the problem of over prescription of the antibiotic drugs. The

Here is a little background on the topic… “What earns bacteria the title superbug? Bacteria can carry traits or genes that allow them to survive exposure to the medicine we currently have.” This means that infections caused by these bacteria are harder to treat, but that doesn't necessarily mean that they are more harmful or infectious. “What is concerning is that the gene that carries antibiotic resistance can be passed between bacteria, allowing

The misuse of antibiotics has the potential to set society back in time to the dark ages. It is time to end the careless use of these valuable antimicrobial that so many take for granted. Antibiotic resistance continues to expand and evolve and solutions to this epidemic need to implemented. By establishing stewardships, educational programs, and restrictions it teaches the severity of this issue and action that must be taken in order to decrease resistance. Antibiotic resistance is a multifactorial issue. Introducing preventative measures in hospitals will be most effective in reducing resistance, as well as eliminating the trend of misusing antibiotics.

This then means that the illness can spread, because the antibiotic has not succeeded in curing it. The way that bacteria form this type of resistance can be explained through natural selection. To start with, there are variations in the bacteria in the way that some are able to resist the antibiotic and some are not. When the bacteria come into contact with an antibiotic, those that are resistant will survive, while the rest will die. These selected bacteria then pass on the characteristics that allow them to resist the antibiotic. This means that over time, the antibiotic will become ineffective against a larger percentage of the bacteria. A new resistant strain of the bacteria has been formed that can survive even when treated with antibiotics, therefore enabling it to be passed to other people. The main cause of this is the overuse or misuse of antibiotics, which allows the bacteria more of a chance to develop a resistance. Some bacteria such as those found in the digestive tract, are naturally resistant to types of antibiotics. Illnesses that have previously been easy to cure with antibiotics are now harder to treat due to antibiotic

The overuse of antibiotics is creating stronger germs; some bacteria is already resistant to antibiotics. Therefore, when bacteria become resistant to antibiotics, it is difficult and costly to treat that infection. The treat to a serious bacterial infection is a big threat to public health.

Antibiotic resistance does not evolve frequently. However, due to the rapid social development, more and more bizarre diseases are appearing around us. The diversity in the standards and perceptions of living has brought us bunch of consequences, including the illogical treatments toward illness and pharmaceutical production. Many people don’t know how to use drugs correctly or refuse to do so; some industry owners know how to properly manage their production lines but refuse to do that. Human’s

The overuse of antibiotics has been a problem for well over a decade. This misuse leads to many nonvisible problems arising within the human population. As the use of antibiotics increases, the number of antibiotic resistant bacteria also increases. When bacteria become resistant to an antibiotic, another antibiotic must be used to try and kill it and the cycle becomes vicious. Michael Martin, Sapna Thottathil, and Thomas Newman stated that antimicrobial resistance is, “an increasingly serious threat to global public health that requires action across all government sectors and society” (2409).

The antibiotic resistance crisis will cause a lot of issues with human development and the health of humanity, to where 80,000 people can die from a single antimicrobial resistance outbreak (3). The reason why this crisis is a