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Antifungal Activity Of Essential Oils

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Antifungal activity of essential oils against respiratory tract pathogens causing Aspergillosis
Abstract:

Invasive Aspergillosis is often found in severely immuno-suppressed patients, and is characterized by invasion of blood vessels which can result into dissemination to other organs. Aspergilloma is a fungal ball that develops in previous cavitary lung lesions. Essential oils and their volatile constituents have been used as antifungal. Inhalation of vapours of the essential oils kill invaders attached to the inner respiratory lining and work synergistically with the body defences. In this study, Five essential oils were used against aspergillus fumingatus using cut plug method and the essential oil showes inhibitory activity against A. flumingatus the most effective oils against A.fumigatus were found to be of Cinnamomum verum (Cinnamon), Lavandula angustifoli (Lavendre), Foeniculum vulgare (Fennel), Zingiber officinale (Ginger) and Cinnamomum camphora(Camphor) with inhibition zones ranging between 11 to 31 mm Treating the organism with cinammom essential oil led to an external changes, irregular cell shape and disintegration of fungus cell wall under transmission electron microscope Analysis by GCMS showed at leas 8 components, esters were the most abundant group of compounds.

The genus Aspergillus includes over 180 species which are ubiquitous and are especially common in soil and decaying vegetation. Around 20 species of the genus Aspergillus have been

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