Asthma causes may include allergens, environmental irritants, respiratory illnesses, sulphites in food, reflux, or medications like beta blockers.2 The airways of asthmatics are narrowed due to the plugging by accumulated mucus, and smooth muscle contraction. During inspiration, the diaphragm moves downwards into the abdomen, and the ribs move upward and outward movement due to diaphragm and inspiratory intercostal muscles’ contraction respectively. This enlarges the lungs due to the changes in intrapleural pressure, and expands the alveoli. Hence, airway resistance decreases during inspiration, because, as the lungs enlarge, the airways within the lung are subject to the same forces as the alveoli, becoming widened. During passive expiration, the inspiratory intercostal muscles relax, causing the lungs to recoil. During active expiration, expiratory intercostal muscles and abdominal muscles contract, decreasing thoracic dimensions, and increasing …show more content…
Adrenoceptor agonists relax airway smooth muscle, and inhibit the release of bronchoconstricting mediators from mast cells. They can also increase mucociliary transport via increasing ciliary activity, and inhibit microvascular leakage. These are achieved through stimulation of adenylyl cyclase, which increase the formation of intracellular cAMP. 2-selective drugs include ephedrine, albuterol, terbutaline, pirbuterol, salmeterol, formoterol, and indacaterol. Anti-inflammatory agents such as an inhaled corticosteroid can provide long-term control. These inhibit the production of inflammatory cytokines, and the infiltration of asthmatic airways by mast cells, lymphocytes, and eosinophils. If taken frequently, these decrease bronchial reactivity, and reduce the frequency of asthma exacerbations. Some inhaled corticosteroids include beclomethasone, budesonide, flunisolide, ciclesonide, fluticasone, mometasone, and
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Asthma is a respiratory disease that many people deal with every single day. “According to World Health Organization, approximately 180,000 people die from asthma each year.” (Jardins and Burton 187) Most people never think of asthma as a life threatening disease, but it can be crucial. As the number of people with asthma increases, the more likely you are to come in contact with someone who has been diagnosed with this disease. Asthma is a severe breathing problem that has many complications that is dealt with daily like shortness of breath, chronic cough, tightness of the chest and shortness of breath, my main focus is childhood asthma, allergic asthma, and medication to treat asthma.
On 2/22/17 Child Protective Services received a referral stating Tristan, comes to school with bites on him, and that he has serve asthma. It is believed the bites came from roaches in the home. has a rash all over his body which he says is from his home being infested with fleas, roaches, rats and mice. Ongoing- Student is almost daily having asthma issues at school. Risk: Jana Shepherd is a parent who has experienced CPS as a teenager with a child.
Fluticasone propionate is a synthetic triflourinated corticosteroid that possess anti-inflammatory properties (RxList). This corticosteroid targets cells and mediators involved in inflammation, having an anti-inflammatory effect on the airways (RxList). Salmeterol Xinafoate is a long acting- beta agonist (LABA), targets the beta2-adrenoceptors that are present in the smooth muscle of the bronchioles (RxList). By targeting the beta2-adrenoceptors, intracellular adenyl cyclase is stimulated, which will lead to the production of more cyclic AMP. An increased level of cyclic AMP then leads to relaxation of the smooth muscle of bronchioles
1.13. In your own words describe how asthma, which is a chronic illness, can become an acute and life threatening emergency? Asthma is a chronic long term issue where the airways become tightened making it harder to breathe. Acute asthma or exacerbation of asthma is when the airways again become tightened and inflamed, swollen and make it hard to breathe which sounds like wheezing, coughing and difficulty in consuming enough oxygen. Can be caused by a allergenic(Chrisp & Taylor, 2011)
The mode of quiet breathing involves the diaphragm and intercostal muscles contracting during the inhalation process. Following the diaphragm muscles contracting, it then travels passively towards the abdominal cavity, resulting in a larger thoracic cavity and an increased lung space. The intercostal muscles also contract, and then moves in an ‘upward and outward’ direction which expands the rib cage and increases chest volume. The expiration process is the opposite of inhalation, this process requires no muscle contractions, instead is influenced by the elasticity of the lungs. As the lungs expand, the elasticity of lung tissue causes the lungs to retreat. This retreat occurs as the diphram and intercostal muscles relax after inhalation.
[Q2] The adrenergic receptors stimulated to improve breathing is the beta-2 receptors. When stimulated, they cause the bronchial muscles to dilate. This dilation relaxes the brachial smooth muscles, allowing for breathing to occur again.
The Australian average statistic for people that smoke is 23.3%. The employed adult average statistic is 84%. Knowing this we can roughly estimate that in the average workplace 1 out of 4-5 people will smoke. The Australian average for people that suffer from asthma is 18%. This makes 1 out of 5 people in the workplace will suffer from some form of asthma. Unfortunately, having smokers allowed to smoke in and around the premise of a workplace limits the interactions the asthma sufferers can have with other workmates as well as limiting the areas the sufferers may go due to the thick, tar soaked air.
The pathophysiology of Asthma includes inflammation of the airway. The way in which this works is from an irritant which can include dust, pollen, cedar, or cat hair. When a reaction occurs, the airways become inflamed and narrow. The narrowing occurs because once the inflammatory response is triggered by an irritant, histamines, immunoglobulin E antibodies, and leukotrienes are released. Because of this, mucous production occurs. Since the bronchioles are inflamed and narrow, breathing becomes difficult. Wheezing sounds can be heard due to the lack of air being able to easily move in and out of the narrowed bronchioles.
The bronchi and bronchiole tubes are loosely wrapped with muscle. During regular breathing, the muscles around these airways are relaxed (5). This allows air to flow freely through these passageways to the alveoli. However, during an asthma attack, air has trouble reaching the alveoli, which prevents the body from receiving oxygen. This is because the airways become smaller. Firstly, the muscles around the airways spasm and contract. This then causes inflammation of the bronchioles and bronchi themselves, which causes a mucus to be produced.
Allergies and asthma are an everyday part of living for many people. Some of these people must avoid eating seafood, others are intolerant of ragweed, and still others might be forced to boycott the zoo because their allergies relate to animals. Animal allergies are no more or less common knowledge than seasonal pollen allergies, but they do sometimes cause a greater change in the behavior of those who suffer the effects. So why are people allergic to animals that they’ve shared the planet with for generations upon generations? And furthermore, if people have allergic responses to some animals, why do they still choose to keep certain ones as house pets? The goal of this paper is to provide an evolutionary perspective on this matter and to determine a cause that is supported by scientific data.
Scientists have for the first time identified the root cause of asthma and the importance CaSR’s in the treatment. As a result they have been able to produce a treatment that counteracts the many side effects associated with asthma. Although researchers have shown calcilytic are able to block the receptors, the longevity of the effect is still unknown. It’s still unclear how long the treatment will stop the lungs producing large numbers of receptors.
Asthma is a chronic lung disease characterized by episodes in which the bronchioles constrict due to oversensitivity. In asthma, the airways (bronchioles) constrict making it difficult to get air in or out of the lungs. Breathlessness is the main symptom. The bronchi and bronchioles become inflamed and constricted. Asthmatics usually react to triggers. Triggers are substances and situations that would not normally trouble an asthma free person. Asthma is either extrinsic or intrinsic. Extrinsic is when the inflammation in the airway is a result of hypersensitivity reactions associated with allergy (food or pollen). Intrinsic asthma is linked to hyper responsive reactions to other forms of
What causes asthma, exacerbations can be caused by multiple different triggers as I have kind of mentioned already. Your body becomes sensitive to certain things. These substances and conditions are your triggers, and can be anything from allergens, dust, mites and small particles. Exactly where asthma comes from is still a mystery. Some people have asthma from birth. “It isn't clear why some people get asthma and others don't, but it's probably due to a combination of environmental and genetic (inherited) factors.” (Mayo Clinic.org) One theory as to where asthma comes from is that it might be inherited from your parents. Another thing that may cause asthma are respiratory infections when you are young. Allergies and viral infections may also
The topic I choose to write about is asthma. The reason being, is because I have personal friends that are close to me that have it, even including family. To get things started I would like to tell you an experience that has happened to us during a high school basketball game. The height of my high school career was playing basketball. Most of the members of the team are my closet friends. Our best shooter on the team was named Odell, an asthmatic. We had a tournament in Naples prior to the week of school starting. Halfway into the second quarter a timeout was called. We all rushed to coach but Odell was slower than the rest of us. He was moving a step or two slower than us. Most people would think he was just exhausted or even upset. Odell