arachidonic acid, taurine, and arginine cannot be synthesized by cats and must be obtained from the diet. Arachidonic acid is a fatty acid, without it, felines may experience reproductive failure and difficulty clotting blood, making it difficult to heal wounds(Zaghini & Biagi, 2005). Taurine is an amino acid found as a free compound in animal tissues. A taurine deficiency in cats can lead to blindness as the retina degenerates (Zaghini & Biagi, 2005). Arginine is also an amino acid, and plays a
The physicochemical and organoleptic qualities of proteins may be refined by controlled enzymatic hydrolysis, which generates free amino acids and abundant short peptides with less salt and carcinogenic compounds (Weir, 1992). Significantly milder conditions are employed: The pH is typically maintained at pH 5–7 corresponding to optimum enzyme activity and the hydrolytic process occurs at 50–60°C for 10–24 h, which minimizes unwanted side reactions (Clemente, 2000). Proteins are only partially hydrolysed
serve as blueprints for protein synthesis during translation. Translation is the process of a protein that is synthesized from information contained by a molecule of messenger RNA. In translation mRNA defined is translated into a 20 letter code of amino
The Role of Folliculin in Amino Acid Sensing SPECIFIC AIMS Birt-Hogg Dubé (BHD) syndrome is a rare autosomal dominant condition that’s characterized by the development of benign skin tumors and lung cysts. Moreover, these manifestations increase patients’ risk to develop renal cell carcinoma (RCC) and/or pneumothorax. Germline mutations in the Folliculin (FLCN) gene are responsible for patients to express the clinical hallmarks of BHD. Most of the BHD patient population contain mutations in the FLCN
nucleic acids. They each play an important role in the synthesis and maintenance of cells. Lipids Lipids are organic compounds such as fats, natural oils, waxes and steroids. They are amphiphilic thus construct structures like vesicles and cell membranes in damp environments. Main functions of lipids are cell signaling, formation of cell membranes and energy storage. (Fahy 2009) There are three main types of lipids found in cells these include fatty acids, phospholipids and steroids. Fatty acids are
a dangerous condition in which over saturation of amino acids in the blood can lead to toxicity progressing to encephalopathy, neurodegeneration, coma or respiratory failure. the etiology of the genetic disease, the mechanism of the genetic disease (if known) MSUD results from a malfunction of the branched-chain alpha-ketoacid dehydrogenase complex (BCKD). This complex produces enzymes necessary for the proper breakdown of common amino acids such as valine, leucine and isoleucine found
a specific amino acid. For example, CAG codes for the amino acid Glutamine and TAT codes for the amino acid Tyrosine. A codon is the base triplets on the mRNA. Each is a copy of the base triplets on the DNA coding strand but in place of the base thymine there is the base uracil (1). Anticodon is a complimentary sequence to the codon base triplets found in mRNA (it is a mirror image). When the mRNA has passed through s pore in the nuclear envelope and arrived at a ribosome, amino acids are brought
synthtaseses attach an amino acid to the transfer RNA. A specific aminoacyl transfer RNA synthestase binds a specific amino acid and a molecule of Adenosine triphosphate to the active site. The bond is broken between the amino acid and Adeonsine monophosphate and the Adenosine monophosphate is then released. At the same time, a covalent bond is formed between the amino acid and the 3’ end of the transfer RNA. A specific transfer RNA has an anticodon that corresponds to the amino acid then binds to the
D1 task 1; protein synthesis Transcription: DNA consists of two strands. One is the coding strand and the other is the template stand. In transcription there is an enzyme called RNA polymerase that ‘unzips’ the two strands. This allows RNA nucleotides (uracil, adenine, guanine and cytosine) to enter the DNA and connect to the corresponding DNA nucleotides (thymine, adenine, guanine and cytosine) on the template strand. After the nucleotides have been paired, phosphodiester bonds, bond the RNA nucleotides
Science Biology Transcript Osteogenesis Imperfecta (OI) Osteogenesis Imperfecta (OI) is an inherited disorder characterized by extreme fragility of the bones also known as ‘brittle bone disease’. Clinical Features The symptoms of OI include malformed bones, short, small body, loose joints, muscle weakness, sclera (whites of the eyes) look purple, grey or blue, triangular face, barrel-shaped rib cage, curved spine, brittle teeth, breathing problems and a collagen deficiency. Classification There