When Rb is mutant: |the generic intercellular pathway is activated. CDK-G1 cyclin is activated and ubiquitinates Rb CDK-G1 cyclin is inactivated and Rb becomes active active Rb protein is phosphorylated by CDK-G1 cyclin and becomes inactive inactive or missing Rb protein is phosphorylated and becomes active active Rb protein becomes a transcription factor and activates genes inactive or missing Rb protein becomes a transcription factor and represses genes active Rb protein inactivates transcription factors and represses genes inactive or missing Rb protein releases transcription factors that activate genes

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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When Rb is mutant:
the generic intercellular pathway is activated.
CDK-G1 cyclin is activated and ubiquitinates Rb
CDK-G1 cyclin is inactivated and Rb becomes active
active Rb protein is phosphorylated by CDK-G1 cyclin and becomes inactive
inactive or missing Rb protein is phosphorylated and becomes active
active Rb protein becomes a transcription factor and activates genes
inactive or missing Rb protein becomes a transcription factor and represses
genes
active Rb protein inactivates transcription factors and represses genes
inactive or missing Rb protein releases transcription factors that activate genes
Transcribed Image Text:When Rb is mutant: the generic intercellular pathway is activated. CDK-G1 cyclin is activated and ubiquitinates Rb CDK-G1 cyclin is inactivated and Rb becomes active active Rb protein is phosphorylated by CDK-G1 cyclin and becomes inactive inactive or missing Rb protein is phosphorylated and becomes active active Rb protein becomes a transcription factor and activates genes inactive or missing Rb protein becomes a transcription factor and represses genes active Rb protein inactivates transcription factors and represses genes inactive or missing Rb protein releases transcription factors that activate genes
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