Using induced pluripotent stem cell technology, cardiac ventricular myocytes were generated using cells taken from Patient X and also from a donor who displayed normal cardiac function. Figure 1.1 displays the action potentials from myocytes expressing either the wild type or the mutant form of channel D. Q 1c. Wild-type channel D 100ms 20mV Mutant channel D 100ms 20mV Figure 1.1. Action potentials recorded from cardiac myocytes expressing either wild type or the mutant form of Channel D. Describe and explain how the mutation in Channel D could lead to the difference in the action potential traces shown in Figure 1.1. [20 marks]
Using induced pluripotent stem cell technology, cardiac ventricular myocytes were generated using cells taken from Patient X and also from a donor who displayed normal cardiac function. Figure 1.1 displays the action potentials from myocytes expressing either the wild type or the mutant form of channel D. Q 1c. Wild-type channel D 100ms 20mV Mutant channel D 100ms 20mV Figure 1.1. Action potentials recorded from cardiac myocytes expressing either wild type or the mutant form of Channel D. Describe and explain how the mutation in Channel D could lead to the difference in the action potential traces shown in Figure 1.1. [20 marks]
Biomedical Instrumentation Systems
1st Edition
ISBN:9781133478294
Author:Chatterjee
Publisher:Chatterjee
Chapter13: Artifacts And Noise In Medical Instrumentation
Section: Chapter Questions
Problem 1CS
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i found this past paper however i cannot find the solutions, please can you answer question 1c
![Using induced pluripotent stem cell technology, cardiac ventricular myocytes were
generated using cells taken from Patient X and also from a donor who displayed normal
cardiac function. Figure 1.1 displays the action potentials from myocytes expressing either
the wild type or the mutant form of channel D.
Q 1c.
Wild-type channel D
100ms
20mV
Mutant channel D
100ms
20mV
Figure 1.1. Action potentials recorded from cardiac myocytes expressing either
wild type or the mutant form of Channel D.
Describe and explain how the mutation in Channel D could lead to the difference in
the action potential traces shown in Figure 1.1.
[20 marks]](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F56a1e488-0afe-4000-88b1-ad107f482cc8%2Fa934df85-29e9-442a-bfa2-f44295ea7ce5%2F0sex0av_processed.png&w=3840&q=75)
Transcribed Image Text:Using induced pluripotent stem cell technology, cardiac ventricular myocytes were
generated using cells taken from Patient X and also from a donor who displayed normal
cardiac function. Figure 1.1 displays the action potentials from myocytes expressing either
the wild type or the mutant form of channel D.
Q 1c.
Wild-type channel D
100ms
20mV
Mutant channel D
100ms
20mV
Figure 1.1. Action potentials recorded from cardiac myocytes expressing either
wild type or the mutant form of Channel D.
Describe and explain how the mutation in Channel D could lead to the difference in
the action potential traces shown in Figure 1.1.
[20 marks]
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