Unlike an intravenously (IV) administrated drug, a drug given orally is unlikely to have reached 100% bioavailability. Which of the following factors influence(s) drug bioavailability of an orally administered drug? O Chemical stability of the drug in the gastrointestinal tract O Nature of the drug formulation O First-pass hepatic metabolism O Solubility of the drug O All of choices are possible factors

Ebk:Nutrition & Diet Therapy
10th Edition
ISBN:9780357391747
Author:DEBRUYNE
Publisher:DEBRUYNE
Chapter16: Specialized Nutrition Support: Enteral And Parenteral Nutrition
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Unlike an intravenously (IV) administrated drug, a drug given orally is unlikely
to have reached 100% bioavailability. Which of the following factors
influence(s) drug bioavailability of an orally administered drug?
Chemical stability of the drug in the gastrointestinal tract
Nature of the drug formulation
First-pass hepatic metabolism
Solubility of the drug
O All of choices are possible factors
Transcribed Image Text:Unlike an intravenously (IV) administrated drug, a drug given orally is unlikely to have reached 100% bioavailability. Which of the following factors influence(s) drug bioavailability of an orally administered drug? Chemical stability of the drug in the gastrointestinal tract Nature of the drug formulation First-pass hepatic metabolism Solubility of the drug O All of choices are possible factors
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