The figure below shows a signaling pathway activated by the binding of ådrenáline to the beta-adrenergic receptor. Binding of adrenaline to the receptor causes GTP-binding and activation of G proteins. Active GTP-boundG protein activates adenylate cyclase to initiate a signaling cascade that affects cellular responses, and includes cellular changes to mediate increased heart rate and accounts for the flight-or-fight response. activated adrenaline activated B-adrenergic receptor adenylate cyclase G protein subunit adenylate cyclase 2/ 3. GTP GDP conformational ATP CAMP change in receptor heterotrimeric G protein ACAMP inactive protein kinase A active protein kinase A cellular responses Consider the homozygous mutation in which a cell produces a variant of the adrenergic receptor that is constitutively active in the absence of ligand. Which of the following are true in this cell? Select all that apply. Protein Kinase A is always activated CAMP concentration is higher than normal Heart rate decreases Heart rate increases
The figure below shows a signaling pathway activated by the binding of ådrenáline to the beta-adrenergic receptor. Binding of adrenaline to the receptor causes GTP-binding and activation of G proteins. Active GTP-boundG protein activates adenylate cyclase to initiate a signaling cascade that affects cellular responses, and includes cellular changes to mediate increased heart rate and accounts for the flight-or-fight response. activated adrenaline activated B-adrenergic receptor adenylate cyclase G protein subunit adenylate cyclase 2/ 3. GTP GDP conformational ATP CAMP change in receptor heterotrimeric G protein ACAMP inactive protein kinase A active protein kinase A cellular responses Consider the homozygous mutation in which a cell produces a variant of the adrenergic receptor that is constitutively active in the absence of ligand. Which of the following are true in this cell? Select all that apply. Protein Kinase A is always activated CAMP concentration is higher than normal Heart rate decreases Heart rate increases
Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter4: Principles Of Neural And Hormonal Communication
Section: Chapter Questions
Problem 18RE
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