The data below depicts the tissue-specificity for mRNA expression of the RAG1 gene in various human tissues. Which of the following are mechanisms that could account for the RAG1 gene being expressed the thymus, but not other tissues (select all that apply)?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
icon
Related questions
Question

The data below depicts the tissue-specificity for mRNA expression of the RAG1 gene in various human tissues. Which of the following are mechanisms that could account for the RAG1 gene being expressed the thymus, but not other tissues (select all that apply)?

 

Kidney. 1
Tonsil.1
Lymphnode.1-
Thymus. 1-
Bonemarrow. 1 9.65
Adrenalgland. 1-
AdrenalCortex. 1-
OlfactoryBulb.1
Tráches.1
Salivarygland. 1
Pituitary. 1
Fetalliver. 1
Fetallung.1
Fetal Thyroid. 1
Uterus. 1
Adipocyte. 1
Pancreaticlslet. 1
Pancreas. 1
Testis SeminiferousTubule.1
TestisLeydigCell.1
TestisIntersitial.1
Testis GermCell.1
Testis. 1
Colorectaladenocarcinoma.1
BronchialEpithelialCells. 1
SmoothMuscle. 1
CardiacMyocytes. 1
Leukemialymphoblastic(MOLT-4).1
Leukemis_chronicMyelogenousk-582.1
Lymphoma_burkitts (Daudi). 1
Leukemis_promyelocytic-HL-60.1
Lymphoms burkitts(Raji). 1
Thyroid. 1
Prostate. 1
Lung.1
Placenta. 1
CD71+ EarlyErythroid. 1
Small intestine. 1
Colon.1
Liver. 1
Heart. 1
250
500
14.70+/-1.20
750
1.00e+3
1032
A. Transcription of RAG1 is regulated by a transcription activator only expressed in the thymus
B. The DNA sequence for RAG1 is only found in thymus
C. An enzyme that modifies histones at the RAG1 promoter is only found in the thymus
D. The transcripton factors that activates RAG1 is activated by a hormone only found in the thymus
E. The transcription factor that regulates RAG1 is sequestered in the cytoplasm in all cell types expcept the thymus
Transcribed Image Text:Kidney. 1 Tonsil.1 Lymphnode.1- Thymus. 1- Bonemarrow. 1 9.65 Adrenalgland. 1- AdrenalCortex. 1- OlfactoryBulb.1 Tráches.1 Salivarygland. 1 Pituitary. 1 Fetalliver. 1 Fetallung.1 Fetal Thyroid. 1 Uterus. 1 Adipocyte. 1 Pancreaticlslet. 1 Pancreas. 1 Testis SeminiferousTubule.1 TestisLeydigCell.1 TestisIntersitial.1 Testis GermCell.1 Testis. 1 Colorectaladenocarcinoma.1 BronchialEpithelialCells. 1 SmoothMuscle. 1 CardiacMyocytes. 1 Leukemialymphoblastic(MOLT-4).1 Leukemis_chronicMyelogenousk-582.1 Lymphoma_burkitts (Daudi). 1 Leukemis_promyelocytic-HL-60.1 Lymphoms burkitts(Raji). 1 Thyroid. 1 Prostate. 1 Lung.1 Placenta. 1 CD71+ EarlyErythroid. 1 Small intestine. 1 Colon.1 Liver. 1 Heart. 1 250 500 14.70+/-1.20 750 1.00e+3 1032 A. Transcription of RAG1 is regulated by a transcription activator only expressed in the thymus B. The DNA sequence for RAG1 is only found in thymus C. An enzyme that modifies histones at the RAG1 promoter is only found in the thymus D. The transcripton factors that activates RAG1 is activated by a hormone only found in the thymus E. The transcription factor that regulates RAG1 is sequestered in the cytoplasm in all cell types expcept the thymus
Expert Solution
steps

Step by step

Solved in 3 steps

Blurred answer
Knowledge Booster
Mutation
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:
9780815344322
Author:
Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:
W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:
9781260159363
Author:
Martin, Terry R., Prentice-craver, Cynthia
Publisher:
McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Inquiry Into Life (16th Edition)
Biology
ISBN:
9781260231700
Author:
Sylvia S. Mader, Michael Windelspecht
Publisher:
McGraw Hill Education