Rate in U [S] in mM No Inhibitor 0.5 1.0 2.0 4.0 8.0 16.0 32.0 64.0 0.22 0.41 0.73 1.12 1.57 2.01 2.3 2.5 3.0 mM Inhibitor Copy and paste the above data into Excel. Create an Eadie-Hofstee plot of the give dataset. 0.08 0.15 0.29 0.52 0.85 1.3 1.78 2.16 Calculate the Vmax, and Vmax/ Km parameters for both the uninhibited and inhibited trials (Inhibited parameters are marked with an apostrophe (')). Finally, determine the mechanism of inhibition. Note: give all parameters to two decimal places, and do not include the units. For th method of inhibition, state competitive, uncompetitive, or mixed as your answer. Vmax 1. Vmax= U-mM-1. Mechanism of inhibition = inhibition N U. Vmax/Km U. Vmax/Km= A U.mM
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- A patient is prescribed venlafaxine 75mg daily for 7 days, increasing by 75mg daily every week until a maximum daily dose of 375mg is reached. A total of 6 weeks treatment must be dispensed. You supply your total stock of 56 venlafaxine 75mg tablets. How many boxes of 28 tablets are still owed to the patient? unit- boxesgraph the data from the table after taking recipocals of [S], V without inhibitor and V with inhibitor. It should be Lineweaver - Burke. use graph paper or excel. however upload graph and answers as 1 document as jpeg, pdf, or word. there should be 2 lines on 1 graph and both lines should cross the Y axis and hit the X axis (negative X axis). label both axes, determine Km and Vmax (show work) in the presence and absence of inhibitor State type of inhibition and if inhibitor resembles the substrate or not. can more substrate relieve the inhibition? [S] (UM) 3 10 30 5 90 Velocity (umol minute-¹) No inhibitor 10.4 14.5 22.5 33.8 40.5 Inhibitor 4.1 6.4 11.3 22.6 33.8Your pharmacy has on hand Tetracycline 250 mg/5 mL liquid.You receive a prescription for Tetracycline syrup 500 mg qid for 7 days. How many total milliliters would you dispense? Your pharmacy has on hand Prednisone 5 mg tablets.You receive a prescription for Prednisone 5 mg ii tabs stat and qid x 1 day, then ii tabs tid x 2 days, then ii tabs bid x 2 days, then i tab tid x 3 days, then i tab bid x 3days, then i tab qd x 4 days How many tablets would you dispense for this prescription? How many days will the patient take this medication for? Your pharmacy has on hand Dilantin 100mg capsules.You receive a prescription for Dilantin 100 mg 1 cap po in the AM & PM, 200mg (2 caps) po at noon, and 300mg (3 caps) po at hs. Dispense a 30 day supply. (using the 100mg capsules you have in stock) How many capsules will you dispense? Your pharmacy has on hand Dakins Irrigation Solution 1 liter.You receive a prescription for Dakins Irrigation Solution Irrigate chest tube with 100 mL…
- You have an order for 1 gram of Cefazolin in D5W 100 ml. You have added 5 ml of sterile water to the 1 gram vial to reconstitute powder. However the recommended manufacturer’s diluent amount is 10 ml of sterile water for a final concentration of 100 mg/ml. How would reconstituting the vial with 5 mls affect the concentration and the final calculated dose?A client has been ordered methyl Pprednisulune 30omg luPB In 30mL D5W Over 15 min.stat fur an asthma att-acis. in Stous,you have methylpredrisolune 500mg vials . The reconstitutiun Instructions are: Add 7.8mL G Sterile uater and shale genly Each reconstituted uial contains 8mL. a) Houw nmuch medieation will you draw up? 6) what is the Infusion rate in mt/ hr ?A patient is receiving morphine sulfate intravenously via a patient controlled analgesia (PCA) pump. The concentration of the solution is 11 mg/mL and is being infused continuously around the clock at a rate of 0.1 mL/hr. The patient may also access a 2-mg bolus dose every hour for breakthrough pain if needed and they are currently using an average of 5 additional bolus doses per day. The patient is to be converted to fentanyl using the table below. But before using the table we must determine their morphine usage, so what is this patient's total daily dosage of IV morphine? TABLE 10.3 FENTANYL TRANSDERMAL DOSAGE CONVERSION GUIDELINES", b Current Analgesic Oral morphine IM/IV morphine Oral oxycodone Oral codeine Oral hydromorphone IV hydromorphone IM meperidine Oral methadone 60-134 10-22 30-67 150-447 8-17 1.5-3.4 75-165 20-44 Recommended fentanyl transdermal system dose Fentanyl transdermal system 25 mcg/h Daily Dosage (mg/day) 135-224 23-37 67.5-112 17.1-28 3.5-5.6 166-278 45-74…
- om/webapps/assessment/take/launch.jsp?course_assessment_id%= 498749_1&course_id%3= 111786 1&content id3= Ac... Customize Links Free Hotmail Windows Windows Media Imported From IE Importe Differential . QUESTION 4 What do you do in between each streak on a streak plate? Dip the loop into the culture252F%252Fbbniagaraccc.sin.suny.edu%252Fwebapps signment Saved He One of the uses of diazepam is as an antiepileptic that can be administered by slow IV infusion at a rate of 0.5 mg/min for 1 hour. If the infusion solution consists of 6 ml and there are 15 drops per milliliter of solution, how many drops per minute should be administered? drops per minuteDoris has reconstituted a bottle of Cefprozil® Oral Suspension to fill a patient's prescription. The prescription calls for 400 mg CefprozilⓇq12h for 7 days. Doris needs to know if the amount of reconstituted medication in the bottle will be enough to last the patient for 7 days. Calculate the total amount of medication in the bottle after this medication has been reconstituted: TEVA Seferle, PA 18960 PHARMACEUTICALS USA SHAKE WELL BEFORE USING KEEP THIS AND ALL MEDICATIONS OUT OF THE REACH OF CHILDREN 5 mL (approx. one teaspoonful) of suspension. Phenylketonurics: This product contains 10.1 mg of phenylalanine per Store constituted suspension in refrigerator. Discard after 14 days Ruv. A 7/2005 L52974 NDC 0093-1075-78 CEFPROZIL for Oral Suspension USP 125 mg/5 mL* Each 5 mL, when constituted according to directions, contains 125 mg anhydrous cetprozil, Ronly 75 mL (when mixed) TEVA To the Pharmacist: Prepare suspension at time of dispensing. Add to the bottle a total of 59 ml water.…
- tablets will you give 3 tablets 11. A client is ordered 100 milligrams of Pehthidine HCL. 50 milligram tablets are available. How many tablets will you give? Etablets 12. A client is ordered 30 milligrams of Codeine phosphate. 60 milligram tablets are available. How many tablets will you give? Stablet 13. A client is ordered 2.5 grams of Neomycin sulphate. 500 milligram tablets are available. How many tablets will you give? 100 d 50cc = 14. A client is ordered 30 milligrams of Diltiazem hydrochloride. 60 milligram tablets are available. How many tablets will you give? 5 tabletTime point (min) Absorbance of culture at 660nm Approximate cell concentration Approximate # cells in 1mL extract 0 0.298 1.49 x 108 cells/mL 1.49 x 108 cells 10 0.316 1.58 x 108 cells/mL 1.58 x 108 cells 20 0.374 1.87 x 108 cells/mL 1.87 x 108 cells 30 0.429 2.145 x 108 cells/mL 2.145 x 108 cells 40 0.512 2.56 x 108 cells/mL 2.56 x 108 cells 50 0.544 2.72 x 108 cells/mL 2.72 x 108 cells 60 0.607 3.035 x 108 cells/mL 3.035 x 108 cells a. Using these data, prepare a growth curve of this strain ofEscherichia coli (E. coli).b. Estimate the doubling time for this strain of E. Coli. Clearly showhow you estimated this value from the empirical data presented.For each of the following examples, indicate whether the drug is acting on physical process, chemical process or enzymatic system (your answer should be only; Physical, Chemical or Enzymatic). Group of answer choices 1. A drug is used as an antidote in lead poisoning and acts by binding to lead particles in body (chelation therapy). 2. A drug acts to reduce flatulence and acts by reducing the surface tension of intestinal gas bubbles in the GI tract (e.g. Simethicone). 3. A drug competes with alpha-glucosidase in intestine to reduce glucose conversion from disaccharides (e.g. Acarbose).