Please help me with this question. More than one answer may be correct. The graph relating to the information is included below. The above graph is looking at the relative entry of SARS-CoV2 isolated spike proteins into human cells in culture at two times points: before introduction of the virus to the cell culture (0 minute) and 5 minutes after introduction of the virus to the cell culture. CHC stands for "clathrin heavy chain" and siRNA stands for small interfering RNA, which is often used in experiments as an easy method to stop expression of a certain gene. So in this case, the CHC siRNA would stop cellular production of CHC. The control siRNA introduces a small RNA fragment that does not match any gene as a negative control. Imagine that the experiment was then allowed to run for 500 minutes in addition to five minutes? How would the relative uptake of the spike protein into the control siRNA cells compare after 500 min to the 5 minute treatment? Options: 500 min time point would have more than 100 times the spike protein uptake as the 5 min time point 500 min time point would have exactly the same amount of spike protein uptake as the 5 min time point 500 min time point would have less than 100 times the spike protein uptake as the 5 min time point 500 min time point would have exactly 100 times the spike protein uptake as the 5 min time point

Essentials of Pharmacology for Health Professions
7th Edition
ISBN:9781305441620
Author:WOODROW
Publisher:WOODROW
Chapter5: Abbreviations And Systems Of Measurement
Section: Chapter Questions
Problem 12CRQ
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Please help me with this question. More than one answer may be correct. The graph relating to the information is included below.

The above graph is looking at the relative entry of SARS-CoV2 isolated spike proteins into human cells in culture at two times points: before introduction of the virus to the cell culture (0 minute) and 5 minutes after introduction of the virus to the cell culture. CHC stands for "clathrin heavy chain" and siRNA stands for small interfering RNA, which is often used in experiments as an easy method to stop expression of a certain gene. So in this case, the CHC siRNA would stop cellular production of CHC. The control siRNA introduces a small RNA fragment that does not match any gene as a negative control. Imagine that the experiment was then allowed to run for 500 minutes in addition to five minutes? How would the relative uptake of the spike protein into the control siRNA cells compare after 500 min to the 5 minute treatment?

Options:

500 min time point would have more than 100 times the spike protein uptake as the 5 min time point

500 min time point would have exactly the same amount of spike protein uptake as the 5 min time point

500 min time point would have less than 100 times the spike protein uptake as the 5 min time point

500 min time point would have exactly 100 times the spike protein uptake as the 5 min time point

Relative spike uptake
150
100-
50
Control siRNA
CHC siRNA
n.s
0 minute
****
H
5 minute
Transcribed Image Text:Relative spike uptake 150 100- 50 Control siRNA CHC siRNA n.s 0 minute **** H 5 minute
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