Identify the type of mutation that occurred to produce the abnormal hemoglobin. Explain why you chose this mutation. Begin by transcribing and translating BOTH the normal and abnormal DNA sequences. The genetic code below is for your reference.

Q: Write an accurate and precise differential report on the sanger sequencing technique

A: The sanger sequencing technique is also called chain-termination method which is made to determined…

Q: What are frameshift mutations with an example

A: Gene mutations are rare and random changes in DNA sequence which result in alteration of polypeptide…

Q: Please explain this statement "Treatment of genetic disorders using gene therapy " Please explain at…

A: GENETIC DISORDER:- A genetic disorder is an illness caused in part or entirely by a deviation from…

Q: What are the particular changes in the gene and protein sequences shown on the screen? Name the…

A: Mutation is the sudden change of a gene or chromosome from one to another. position 3 wild type…

Q: Identify which mutagen is described by the following statement. Results to the formation of thymine…

A: Thymine dimer: a. It consists of two adjacent pyrimidine nucleotides, which are usually thymine…

Q: From your knowledge about DNA microarray, answer the following: Mention the name and the color of…

A: DNA microarray is basically a collection of microscopic DNA spots that are attached to the solid…

Q: Write a report on the controversy over NgAgo gene-editing along with your personal opinion?

A: Genome editing is a molecular biology tool which scientist uses to edit the genome of an organism to…

Q: What is the transcribed sequence

A: Sequence that is transcribed from the template DNA using complementary base pairing rules are known…

Q: Give a schematic diagram of how we can Treatment Sickle Cell Anemia by using gene therapy? Please…

A: Sickle cell anemia can be defined as the clinical condition which occurs because of a defect in…

Q: Could you please explain to me what the following terms mean; “methylase”, “methylates” and…

A: Methylase: it is an enzyme that causes methylation, addition of methy group (CH3) on the substrate.…

Q: What do the spacers within the CRISPR region correspond to?

A: CRISPR that is clustered regularly interspaced short palindromic repeats. It is found in the…

Q: what is a palindromic sequence?

A: If a nucleic acid sequence in a double stranded DNA or RNA molecule is read in a particular…

Q: Please describe the Watson-Crick proposal.

A:

Q: Name the mapping technique used to determine the position of restriction sites in a DNA molecule.

A: DNA or deoxyribonucleic acid is a polymer of deoxyribonucleotides connected together via…

Q: Why is it a large undertaking to construct a DNA library?

A: A deoxyribonucleic acid library could be an assortment of cells that carry cloned items of the whole…

Q: What different methods were used to help break the genetic code? What did each method reveal and…

A: The genetic code is a triplet code, in which three nucleotides encode each amino acid in a protein.…

Q: How was the genetic code deciphered?

A: Answer: Introduction: The Nirenberg and Matthaei experiment was a logical research done in May 1961…

Q: What do you mean by restriction fragments?

A: Recombinant DNA technology is the process of combining two or more DNA fragments from a different…

Q: What do you understand by treatment of genetic disorders using gene therapy?  Please answer at your…

A: GENETIC DISORDER:- A genetic disorder is an illness caused by a change in an individual's DNA…

Q: Compare, substitution, insertion, deletion to the normal gene.

A: Mutation refers to the alteration of the nucleotide sequence of the gene. Types of mutation include…

Q: What does SDS–PAGE stand for? What is the benefit of doing SDS– PAGE?

A: Electrophoresis is the migration of charged particles under the influence of an electric current.…

Q: How do you use CRISPR to treat a patient with sickle cell anemia? Please provide a detailed…

A: In sickle cell anemia the blood cells become sickle shaped. This may result into painful blood flow,…

Q: Where does the primer come from?

A: Naturally, Primers are single-stranded nucleic acid sequences that initiate the synthesis of DNA…

Q: Why was it risky for the chinese scientist to change the twin’s genome sequence?

A: It was risky for the chinese scientist to change the twin's genome sequence as it may lead to more…

Q: Draw the structure of a typical insertion sequence and identify its parts.

A: There are two types of transposons such as replicative and non-replicative transposons. They are…

Q: What is meant by the phrase reading frame?

A: The genetic sequence is comprised of nucleotides, which are joined together to form polynucleotides…

Q: Why was sequencing the human genome such a formidable task?

A: Human Genome Project is a project which tells about the DNA sequence of the complete human genome.…

Q: Describe the purpose and process of DNA finger printing.

A: DNA fingerprinting is the method of recognizing the genetic makeup of individuals through the…

Q: What is a read (Sanger sequencing)?

A: DNA sequencing is the process of determining the sequence of nucleotides (adenine, guanine,…

Q: How we can select Tm value for the primers? Please answer at your own words.

A: DNA replication is considered a biological process during cell division, where DNA can make a copy…

Q: Explain why an investigator might want to create aconditional knockout mouse.

A: A conditional Knockout mouse defines an animal model in which a gene of interest can be: inactivated…

Q: TACAT

A: Solution :There are three types of DNA Mutations: base substitutions, deletions and insertions.

Q: Consider the following wild-type and mutant sequences:Wild-type ....CTTGCAAGCGAATC....Mutant…

A: Introduction A mutation occurs when the sequence of DNA changes. Mutations can occur as a result of…

Q: gene definition

A: Allele are considered as  the variant of the gene. DNA is composed of different nucleotides that…

Q: riefly explain this Statement "Treatment for the genetic disorders by using gene therapy "

A: Gene therapy includes changing the genes inside your body's cells with an end goal to treat or stop…

Q: Refer to the figure. What method would you use if you wanted to determine the sequence of the cDNA…

A: cDNA is complementary DNA. This DNA is artificially synthesized from the mRNA template. In genetic…

Q: Name the scientist who developed a DNA sequencing technique. Understand the sequencing technique

A: The method of determining the order of nucleotides that are adenine, thymine, cytosine, and guanine…

Q: Draw an annotated diagram outlining the steps involved in a Next Generation sequencing technology of…

A: DNA is the genetic material of almost all living organisms. It consists of a ribose sugar, a…

Q: translation

A: m RNA strand is 5' - AAG AUG GCG UUU UAA CCG -3'

Q: Describe how a mutation can occur using the image shown

A: A nucleotide is an organic molecule that serves as the foundation for DNA and RNA. They also play…

Q: What is a Sanger Sequencing ?

A: The term DNA sequencing encompasses biochemical methods for determining the order of the nucleotide…

Q: Define Reading frame as they apply to the genetic code

A: The central dogma of life is- DNA ---> mRNA ---> Protein The process of formation of mRNA from…

Q: Draw a diagram of how we can treatment the Sickle cell anemia by using gene therapy?  Please draw at…

A: Gene therapy is a technique that modifies a person's genes to treat or cure disease. Gene therapy in…

Q: Please Write at your own words -Explain this How we can treatment for the genetic disorders by using…

A: Gene therapy is the introduction of a normal functional gene into cell that content defective allele…

Q: Write and discuss about the analysis procedure used for carrier screening for the single-gene…

A: Carrier screening is a  genetic test that determine whether the individual is carrying a gene for…

Q: What key molecules are essential for Sanger sequencing?

A: DNA sequencing is used to determine the exact arrangement of the nucleotide bases adenine (A),…

Q: Discuss what is meant by the term genome

A: Organisms are classified as monoploid, diploid, triploid, tetraploid, etc based on the number of…

Q: If you have access to the necessary computer software, make asequence file and analyze it in the…

A: The sequencing of genetic information is important for proper study and analysis, and with the…

Gene Interactions

When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.

Gene Expression

Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.