How does bisulfite treatment coupled with PCR enable the identification of DNA methylation? And, How could a Southern blot be used to determine if a given DNA sequence contains methylated CpGs in paper "Amyloid-β Alters the DNA Methylation Status of Cell-fate Genes in an Alzheimer's Disease Model." Taher, N., McKenzie, C., Garrett, R., Baker, M., Fox, N., & Isaacs, G. D. (2014). Amyloid-β alters the DNA methylation status of cell-fate genes in an Alzheimer’s disease model. Journal of Alzheimer’s Disease: JAD, 38(4), 831–844. https://doi.org/10.3233/JAD-131061

How does bisulfite treatment coupled with PCR enable the identification of DNA methylation? And, How could a Southern blot be used to determine if a given DNA sequence contains methylated CpGs in paper "Amyloid-β Alters the DNA Methylation Status of Cell-fate Genes in an Alzheimer's Disease Model." Taher, N., McKenzie, C., Garrett, R., Baker, M., Fox, N., & Isaacs, G. D. (2014). Amyloid-β alters the DNA methylation status of cell-fate genes in an Alzheimer’s disease model. Journal of Alzheimer’s Disease: JAD, 38(4), 831–844. https://doi.org/10.3233/JAD-131061

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter14: Biotechnology And Society

Section: Chapter Questions

Problem 7QP

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