A total of 1000 members of a Central American population are typed for the ABO blood group. In the sample, 421 have blood type A, 168 have blood type B, 336 have blood type O, and 75 have blood type AB. Part A Use this information to determine the frequency of ABO blood group alleles in the sample. Recall that when considering genes with three alleles whose frequencies are represented by the variables p, q, and r, the sum of genotype frequencies resulting from trinomial expansion is: (p+q+r)² =p² + 2pq+q2+2pr+r²+2gr = 1

A total of 1000 members of a Central American population are typed for the ABO blood group. In the sample, 421 have blood type A, 168 have blood type B, 336 have blood type O, and 75 have blood type AB. Part A Use this information to determine the frequency of ABO blood group alleles in the sample. Recall that when considering genes with three alleles whose frequencies are represented by the variables p, q, and r, the sum of genotype frequencies resulting from trinomial expansion is: (p+q+r)² =p² + 2pq+q2+2pr+r²+2gr = 1

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter19: Population Genetics And Human Evolution

Section: Chapter Questions

Problem 9QP: Using the HardyWeinberg Law in Human Genetics Suppose you are monitoring the allelic and genotypic...

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A worldwide survey of genetic variation in human populations reported the autosomal codominant MN blood group types in a sample of 1029 Chinese individuals from Hong Kong. The sample contained 342 people with blood type M, 500 with blood type MN, and 187 with blood type N. Part A The number of people expected in each blood-type category is: Enter the values expected for MM, MN and NN blood-type categories, respectively, separated by commas and using two decimal places (example 1.02, 2.30, 3.45).
A total of 6129 North American Caucasians were blood typed for theMN locus, which is determined by two codominant alleles, LM and LN.The following data were obtained:Blood type NumberM 1787MN 3039N 1303Use a chi-square test to determine whether this population is in Hardy–Weinberg equilibrium at the MN locus.
Consider the MN blood system in humans. This blood system consists of only two alleles, M and N, and they are codominant to each other. Three genotypes are possible, and these genotypes can be easily identified through simple blood typing procedures, including the heterozygous MN due to the codominant mode of inheritance. Consider the following data: Phenotype Genotype Number of individuals M MM 89 MN MN 162 N NN 79 1. How many alleles exist in this population? 2. What is the genotypic frequency of the M blood type in the population? 3. What is the allelic frequency of M? 4. What is the allelic frequency of N? 5. What is the genotypic frequency of MN? Write your answers directly. You do not need to show your solution.
A total of 6129 North American Caucasians were blood typed for the MN locus, which is determined by two codominant alleles, LM and LN. The following data were obtained: Blood type Number M 1787 MN 3039 N 1303 Carry out a chi-square test to determine whether this population is in Hardy–Weinberg equilibrium at the MN locus.
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Consider two blood polymorphisms that humans have in addition to the ABO system. Two alleles LM and LN determine the M, N, and MN blood groups. The dominant allele R of a different gene causes a person to have the Rh+ (rhesus positive) phenotype, whereas the homozygote for r is Rh− (rhesus negative). Two men took a paternity dispute to court, each claiming three children to be his own. The blood groups of the men, the children, and their mother were as follows:From this evidence, can the paternity of the children be established?
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Give nine examples of lethal alleles in humans, other animals, and plants and a brief molecular explanation (i.e., why are they lethal).
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