A gene normally contains an N' terminal ER signal sequence and an internal stop transfer sequence. The ER signal sequence is recognized and used during the protein trafficking process, as normal. After translation is completed a signal peptidase enzyme cleaves the N' ER signal sequence but the internal sequence is not cleaved. Which of the following figures best represents the orientation of the protein product after translation? N Extracellular Extracellular Extracellular Extracellular N' C' Lumen Lumen Lumen Lumen N' A Oc O A В

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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gene normally contains an N' terminal ER signal sequence and an internal stop
transfer sequence. The ER signal sequence is recognized and used during the protein
trafficking process, as normal. After translation is completed a signal peptidase
enzyme cleaves the N' ER signal sequence but the internal sequence is not cleaved.
Which of the following figures best represents the orientation of the protein product
after translation?
N
Extracellular
Extracellular
Extracellular
Extracellular
-N'
C'
N
Lumen
Lumen
Lumen
Lumen
N'
A
В
C
Transcribed Image Text:gene normally contains an N' terminal ER signal sequence and an internal stop transfer sequence. The ER signal sequence is recognized and used during the protein trafficking process, as normal. After translation is completed a signal peptidase enzyme cleaves the N' ER signal sequence but the internal sequence is not cleaved. Which of the following figures best represents the orientation of the protein product after translation? N Extracellular Extracellular Extracellular Extracellular -N' C' N Lumen Lumen Lumen Lumen N' A В C
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