2) An individual plasma [Na+] is measured and found to be 130 mEq/L (normal = 145 mEq/L). What is the patient's estimated plasma osmolality? (Normal osmolality of the plasma is 290 mOsm/Kg H2O).
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- What are major factors that determine blood osmolality? The osmolality of 0.9% NaCl is ___________. How is the osmolality different from the molarity? Also, predict the effect of 1 L of 600 mOsm/L infusion of sucrose on patients RBC’s osmolality and volume, if previous osmolality of RBC’s was 250 mOsm/L, plasma volume – 3.6 L and RBC’s volume – 2.4 L.A 5% dextrose is isoosmotic to plasma. What effect would infusion of 1L of a 5% dextrose solution have on ECF and ICF volumes? How it would affect body fluid osmolality of a 70 kg individual and why?A 60-year-old woman with history of lung cancer is admitted for weakness and lethargy for 4 weeks. Her serum [Na*] is 120 mEq/L. She weighs 60 kg. Her serum osmolality is 250 mOsm/kg H2O with urine osmolality of 616 mOsm/kg H2O. The diagnosis of SIADH is made. What would be her serum [Na], if she receives 1 L of isotonic saline? A. 122 mEq/L B. 116 mEq/L C. 118 mEq/L D. 120 mEq/L E. 124 mEq/L
- 35. Identify the osmolality (including units) of MOST body fluids (cytosol, ISF, blood, CSF, etc.) vs. the osmolality range created and maintained in the renal medulla ISF by the countercurrent mechanism. Include the units. I Most body fluids except urine Renal medulla ISF Urine7.Your patient weights 160 lbs. Her hematocrit is 43%. Calculate her blood volume in L 8.Your patient weights 150 lbs. Calculate her ISF volume in L 9. The 10-month old patient with hyponatremia (from our osmolarity case study) had a serum osmolarity of 255 mOsm/L. Given the normal neuronal osmolarity of 300 mOsm/L, answer the following: A. Compared to the neuronal ICF, is the ECF space hyperosmotic/hyposmotic/isosmotic? B. What effect does this have on the neurons? ( C. What effect might this have on the brain? Why? 9.A 68-year-old lady with bowel cancer who had been admitted to hospital following a fall had a persistent low plasma sodium including the following plasma results (refer- ence ranges are given in brackets): Sodium Potassium Urea Creatinine Glucose Osmolality 120 mmol/L 3.9 mmol/L 3.4 mmol/L 53 μmol/L 5.2 mmol/L 255 mOsm/kg (135-145) (3.5-5.0) (3.5-6.6) (70-150) (3.5-5.5) (285-305) In this patient, the urine volume was low and relatively concentrated, the urine osmo- lality was 374 mOsm/kg and its sodium concentration was 75 mmol/L. Comment on these results.
- At 10 am you received a doctors order that you have to Infuse 1,000ml of PNSS in 10 hours to Mr. Dela Cruz. What is the correct rate of this isotonic solution when the drop factor is 10 gtt = 1ml? 15.73 qtts/min- 31.249 qtts/min 16.67 qtts/min 18 qtts/minA normal saline solution (0.9 mg of sodium chloride per 100 ml of solution) is given intravenously and a total of 0.5 L of the solution was given over a 4 hour period. What is the flow rate in units of milliliter per hour?. What is the flow rate in units of mg ( of sodium chloride) per hour?. During 4 hour period how much sodium chloride is delivered?Calculate the flow rate for a solution of 18 mg in 300 mL with a maintenance dose of 5 mcg/min.
- Adult male suffered myocardial infarction and is currently in cardiogenic shock. Blood pH = 7.25, [HCO3-] = 14 mmol/L, PaCO2 = 38 mmHg. What kind of acid-base imbalance is the patient suffering from? Briefly describe fully how this occurred.At 8 am you received a doctor order that you have to Infuse 1, 500 ml of D5W in 12 hours to Mr. Dela Cruz. What is the correct rate of this isotonic solution when the drop factor is 15gtt =1m? 29 qtts/min 34 qtts/min 31 qtts/min 15 qtts/minBlood plasma has an osmolarity of about Group of answer choices: 100 mOsm/L. 900 mOsm/L. 1200 mOsm/L. 300 mOsm/L. 30 mOsm/L.