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- 44. Parkinson’s disease, Huntington’s disease and Ataxia are motor dysfunctions. Describe and explain the hallmarks/symptoms and the affected brain regions /neurons affected per each disorder.6. The pathophysiology of the Parkinson's disease.?Write notes on clinical strategies for the treatment of (a) Huntington's disease and (b) amyotrophic lateral sclerosis. Include one example of a novel therapeutic strategy currently being investigated for each of these diseases.
- You are called to assess a pt complaining of severe back pain originating at L4 and running down the back of his right thigh and inner right leg. You also observe an associated weakness and sensory deficit in the right leg. which of the following would be the most consistent with these findings A) Sciatica B) Cerebal Palsy C) L4 Lumbar Fracture D) Cerebrovascular accidentDescribe in detail the link between neuroiflammation and Parkinson disease.6. Explain what functional neurologic disorder means. What are some of the challenges that health care practitioners experience when treating persons who may have functional neurologic disorder? Having been made aware of what functional neurologic disorder is, what does this tell you about the state of knowledge regarding the brain and disease?
- 1. Answer BOTH parts of this question (a)Describe in detail the role in the pathogenesis of Alzheimer’s Disease of neurofibrillary tangles, amyloid plaques and E-secretase (b) Evaluate the cholinergic pharmacological agents for the treatment of Alzheimer’s Disease.Q1) A 30 year old male presents to outpatient rehabilitation with previous history of shoulder pain and limited passive ROM .Now the patient complain numbness and tingling on the 4th and 5th fingers of the left hand .Upon further examination, it is noted that the patient has normal sensation on the dorsum of the hand on the ulnar side. 1)What is the possible diagnosis of patient? 2)Where is the most likely source of nerve entrapment and justify your answer? 3)Which nerve will be injured and what will be further symptoms of patient? 4)Would the condition of the patient is suitable for physiotherapy or will refer to some surgeon for further consultation?15. A 22-year-old man is brought to the emergency department 1 hour after being involved in a motor vehicle collision. Neurologic examination shows inaccurate finger-to-nose movements of the left upper extremity. He has an ataxic gait with a tendency to fall to the left. This patient most likely has a lesion in which of the following structures? A) Cerebellar hemisphere on the left B) Cerebellar hemisphere on the right C) Corticospinal tract on the left D) Corticospinal tract on the right E) Vestibular semicircular canals on the left F) Vestibular semicircular canals on the right
- Explain three (3) signs and symptoms of MS(a) Define cerebrovascular accident or CVA. (b) Describe its possible causes and consequences.1 What is the pathophysiology of Parkinson's disease? a. Progressive nervous system disorder that affects movement b. Neural tube dysfunction c. Genetic disorder d. Progressive weakness and loss of muscle mass