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Biostatistics Student Journal Club

Satisfactory Essays

Biostatistics Student Journal Club Questions and Answers 10/17/2016 Group #12: Jenna Nixon, Vu Le, Sarah Jacob, Kajri Shah, Andres Brito, Isis Sanders Question #1: What was the null hypothesis of the study and was it accepted or rejected? Answer: The null hypothesis was that there is no association between lower blood sugar and taking the oral glucagon receptor antagonist LY2409021 in healthy and diabetic individuals. The study found that taking the glucagon receptor antagonist does indeed help lower blood sugar in healthy and diabetic individuals with very limited hypoglycemia; therefore, the null hypothesis was rejected Question #2: What ethical guidelines, if any, were used during this research study? Answer: The study used the Declaration …show more content…

Answer: The primary objective was to test if the glucagon receptor antagonist use is safe and if study participants will be able to tolerate the drug. Also, they wanted to test the therapeutics effect of the LY2409021 drug on the study participants and how the participants’ body will affect the drug. Question #4: What measurements were conducted during the study to ensure that the participants were safe? Answer: The subjects in the study were regularly tested on their vital signs, echocardiogram and clinical laboratory tests. Question #5: Was this journal peer reviewed and what was its impact factor? Answer: The journal (Diabetes, Obesity, and Metabolism) had a journal impact factor of 6.198 in 2015, according to InCites. The journal, however, is not peer-reviewed per Ulrich’s Periodicals Directory. Question #6: How were the participants selected for the studies? Answer: The study participants for the studies were selected based on the following criteria: For Type 2 Diabetes Study Participants: Hemoglobin A1C level that 11.1/1, following an oral glucose tolerance test For Healthy Study Participants: BMI 18.5–29.9 kg/m2, Fasting blood glucose level of

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