Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN: 9781305389892
Author: Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher: Cengage Learning
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Chapter 9, Problem 14TYK
Discuss Concepts Why do you suppose cells evolved internal response mechanisms using molecules that bind GTP instead of ATP?
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Why is the GTPase activity of G proteins crucial to the proper functioning of a cell? Propose a theory as to why G proteins have not evolved to catalyze GTP hydrolysis more efficiently.
Researchers use a technique call RNA interference to knock down (i.e. not completely gone) the Bcl-2 gene in the amygdala of lab animals. What cellular response would you expect to occur?
Question 1 options:
A)
An increase in apoptosis; many cells in the area would die
B)
An increase in axon regrowth after injury
C)
A decrease in cytochrome c levels released from the mitochondria
D)
A decrease in glial cell infiltration after injury
compare and contrast how GPCRs and RTKs transduce their signal to the cell? include the types of ligands they bind, the GTP binding protein that is activated, and how the signal is transduced and amplified. what effects does it have on the cell?
Chapter 9 Solutions
Biology: The Dynamic Science (MindTap Course List)
Ch. 9.1 - What accounts for the specificity of a cellular...Ch. 9.2 - Prob. 1SBCh. 9.2 - Prob. 2SBCh. 9.3 - Prob. 1SBCh. 9.3 - Prob. 2SBCh. 9.3 - Prob. 3SBCh. 9.3 - Prob. 4SBCh. 9.3 - Prob. 5SBCh. 9.3 - Prob. 6SBCh. 9.4 - What distinguishes a steroid receptor from a...
Ch. 9.4 - By what means does a specific steroid hormone...Ch. 9.5 - Prob. 1SBCh. 9 - In signal transduction, which of the following is...Ch. 9 - Which of the following could not elicit a signal...Ch. 9 - A cell that responds to a signaling molecule is...Ch. 9 - Prob. 4TYKCh. 9 - Prob. 5TYKCh. 9 - Which of the following is incorrect about pathways...Ch. 9 - Which of the following would not inhibit signal...Ch. 9 - Prob. 8TYKCh. 9 - Prob. 9TYKCh. 9 - Prob. 10TYKCh. 9 - Discuss Concepts Describe the possible ways in...Ch. 9 - Discuss Concepts Is providing extra insulin an...Ch. 9 - Discuss Concepts There are molecules called GTP...Ch. 9 - Discuss Concepts Why do you suppose cells evolved...Ch. 9 - How would you set up an experiment to determine...Ch. 9 - Prob. 16TYKCh. 9 - Prob. 1ITDCh. 9 - Prob. 2ITDCh. 9 - Prob. 3ITD
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- The video showed one way that a G protein-coupled receptor (GPCR) can deliver a signal using heterotrimeric G proteins. Place the steps in this signal transduction pathway in the correct order, starting with the earliest on the left and the latest on the right. Drag all steps into the box below, placing them in the correct order from first to last. Avoid stacking answers on top of each other. The Gs alpha subunit dissociates ATP is converted to cyclic AMP First step GDP is exchanged for GTP on the G protein Ligand binding to the GPCR Reset Help Adenylyl cyclase is activated Last steparrow_forwardWhy is the GTPase activity of G proteins crucial to the proper functioning of a cell? Why have G proteins not evolved to catalyze GTP hydrolysis more efficiently?arrow_forwardWhich of the following statements is false? Question 11 options: a) Nucleotides and amino acids can act as extracellular signal molecules. b) Some signal molecules can bind directly to intracellular proteins that bind DNA and regulate gene transcription. c) Some signal molecules are transmembrane proteins. d) Dissolved gases such as nitric oxide (NO) can act as signal molecules, but because they cannot interact with proteins they must act by affecting membrane lipids.arrow_forward
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Intro to Cell Signaling; Author: Amoeba Sisters;https://www.youtube.com/watch?v=-dbRterutHY;License: Standard youtube license