A.
To explain: The part of the viral protein which gives rise to the peptide that is recognized by the clone of cytotoxic T cells.
Concept introduction: T cells and B cells are lymphocytes of the immune system which helps to elicit an immune response against an invading pathogen. T cells are antigen-presenting cells (APC). There are three types of T cells: Cytotoxic T cells, Helper T cells and memory T cells. There are other minor types of T cells like natural killer T cell, γδ T cells and many more. The main function of cytotoxic T cells represented as TC have T-cell receptors on the surface of their plasma membrane that has the capacity to recognize specific antigens that can be even nuclear proteins of the pathogen.
To explain: The reason why all viral peptides do not sensitize the target cells for lysis by the cytotoxic cells.
Concept introduction: T cells and B cells are lymphocytes of the immune system which helps to elicit an immune response against an invading pathogen. T cells are antigen-presenting cells (APC). There are three types of T cells: Cytotoxic T cells, Helper T cells and memory T cells. There are other minor types of T cells like natural killer T cell, γδ T cells and many more. The main function of cytotoxic T cells represented as TC have T-cell receptors on the surface of their plasma membrane that has the capacity to recognize specific antigens that can be even nuclear proteins of the pathogen.
B.
To explain: The way in which the experiment worked when MHC molecules come to cell surface with peptides already bound.
Concept introduction: T cells and B cells are lymphocytes of the immune system which helps to elicit an immune response against an invading pathogen. T cells are antigen-presenting cells (APC). There are three types of T cells: Cytotoxic T cells, Helper T cells and memory T cells. There are other minor types of T cells like natural killer T cell, γδ T cells and many more. The main function of cytotoxic T cells represented as TC have T-cell receptors on the surface of their plasma membrane that has the capacity to recognize specific antigens that can be even nuclear proteins of the pathogen.
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