Concept explainers
Interpretation: The starting carbonyl materials that are needed to prepare X by using a directed aldol reaction are to be identified. The reagents that are needed to convert X to donepezil are to be identified.
Concept Introduction: The directed aldol reaction is a type of cross aldol reaction. This directed aldol reaction categorizes the carbonyl compounds into the nucleophilic enolate and other the carbonyl compound which can react at the electrophilic carbonyl carbon atom.
Aldol reaction is the condensation reaction of the
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Organic Chemistry
- What is the general name for the reaction product formed in an aldol addition reaction? O y-Hydroxy carbonyl compound a,B-Hydroxy carbonyl compound O a-Hydroxy carbonyl compound O B-Hydroxy carbonyl compoundarrow_forwardThe following molecule can be formed via an intramolecular aldol addition reaction. Draw the organic starting material needed to form the given B-hydroxycarbonyl compound. organic starting material B-hydroxycarbonyl NaOH OHarrow_forwardDraw the product formed when each dicarbonyl compound undergoes an intramolecular aldol reaction followed by dehydration, when possible.arrow_forward
- What aldehyde or ketone is needed to prepare each compound by an aldol reaction?arrow_forwardWhy is the Aldol reaction often called an Aldol condensation? 1) The initially formed b-hydroxy carbonyl compound loses an oxygen atom 2) The initially formed b-hydroxy carbonyl compound loses a hydrogen atom 3) The initially formed b-hydroxy carbonyl compound loses water 4) The initially formed b-hydroxy carbonyl compound loses a hydroxyl grouparrow_forwardWhat product result from nitration of benzaldehyde ?arrow_forward
- Draw reaction of an Α,β -unsaturated carboxylic acid derivative with a nucleophile forms a nucleophilic acyl substitution product with a reactive carbonyl group and a conjugate addition product with a less reactive carbonyl grouparrow_forwardDraw the product formed when phenylacetic acid (C6H5CH2COOH) istreated with following reagent. With some reagents, no reaction occurs. NaOHarrow_forwardDraw the product formed when each organometallic reagent is treated with H2O.arrow_forward
- Organic Chemistry: A Guided InquiryChemistryISBN:9780618974122Author:Andrei StraumanisPublisher:Cengage Learning