Microbiology Fundamentals: A Clinical Approach
3rd Edition
ISBN: 9781259709227
Author: Marjorie Kelly Cowan Professor, Heidi Smith
Publisher: McGraw-Hill Education
expand_more
expand_more
format_list_bulleted
Question
Chapter 14, Problem 1VC
Summary Introduction
To determine:
How abnormality in bone marrow and thymus can lead to immune deficiency.
Concept introduction:
B-cell and T-cell are the components of immune system. B-cells provide humoral immunity and are known to develop from hematopoietic stem cells present in bone marrow. T-cells provide cell-mediated immunity and are known to originate in the hematopoietic stem cells but mature in the thymus.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
T-independent humoral immunity may be stunted in children because __________.
View Available Hint(s) for Part A
the repertoire of T cells in children is not fully developed
T cells are overactive in children
children have a weak ability to produce tumor necrosis factor
the repertoire of B cells in children is not fully developed
Match the lymphoid tissue to its function. Some answers may be used more than once. Some questions may have more than one correct response.
1. Transfers excess fluid in the blood to the lymphatic system2. Matures T cells3. Defends against pathogens entering the mouth or nose4. Protects against pathogens in the urinary tract5. Filters lymph
a. Thymus glandb. Lymph nodesc. MALTd. Spleene. Tonsils
List 3 things that helper T cells do:
Chapter 14 Solutions
Microbiology Fundamentals: A Clinical Approach
Ch. 14.1 - Define immunopathology, and identify the two major...Ch. 14.1 - Identify the four major categories of...Ch. 14.2 - Summarize genetic and environmental factors that...Ch. 14.2 - Identify three conditions caused by IgE-mediated...Ch. 14.2 - Identify the two clinical forms of anaphylaxis,...Ch. 14.2 - List the three main ways to prevent or...Ch. 14.2 - NCLEX PREP 1. During a visit to his physician, a...Ch. 14.2 - Prob. 2NPCh. 14.3 - List the three immune components causing cell...Ch. 14.3 - Prob. 8AYP
Ch. 14.4 - Prob. 9AYPCh. 14.4 - Medical Moment Patch Testing Patch testing is an...Ch. 14.5 - Prob. 10AYPCh. 14.5 - List four classes of grafts, and explain how host...Ch. 14.5 - NCLEX PREP 3. A patient receives a kidney...Ch. 14.6 - List at least three autoimmune diseases and the...Ch. 14.7 - Distinguish between primary and secondary...Ch. 14.7 - Medical Moment Hand Washing The importance of hand...Ch. 14.7 - Prob. 4NPCh. 14 - Allergy and atopy might have evolved in human...Ch. 14 - Can you think of a reason why humans have evolved...Ch. 14 - Prob. 3QCh. 14 - Prob. 4QCh. 14 - What feature of antibodies makes them particularly...Ch. 14 - Prob. 6QCh. 14 - Prob. 7QCh. 14 - Prob. 8QCh. 14 - Epi-pens are devices used to instantly inject a...Ch. 14 - Prob. 10QCh. 14 - Steroids administered to stop an allergic response...Ch. 14 - A very small number of people have a condition...Ch. 14 - Prob. 13QCh. 14 - Prob. 14QCh. 14 - Recent research shows that asthmatic patients have...Ch. 14 - Which statement is true of autoimmunity? a. It...Ch. 14 - It is often said that the normal microbiota of a...Ch. 14 - Investigate the link between Streptococcus...Ch. 14 - Which disease would be most similar to AIDS in its...Ch. 14 - Do you think people with B-cell deficiencies can...Ch. 14 - The chapter tells us that the gut microbiome of...Ch. 14 - Prob. 1VC
Knowledge Booster
Similar questions
- Secondary lymphoid organs, such as the lymph nodes, spleen, and mucosa-associated lymphoid tissues, each have distinct features that are important for their role in initiating immune responses focused on different anatomical compartments (i.e., the peripheral tissues, the blood, or the gastrointestinal tract, respectively). Yet these organs share some overall structural features, such as distinct T-cell and B-cell zones. One major difference between these organs is: The presence versus the absence of macrophages and dendritic cells Their function in bringing rare naive lymphocytes into contact with their specific antigen The ability of lymphocytes to enter the organ from the blood The mechanism by which antigens or pathogens enter the organ The ability of naïve T cells to be activated and proliferate in the organarrow_forwardTrue/False: Dendritic cells are tissue resident myeloid cells that are highly phagocytic, like macrophages. However, dendritic cells do not play a major role in large-scale pathogen destruction; instead, they are important in initiating adaptive immune responses of T cells.arrow_forwardWrite T if the statement is correct; write F if the statement is not correct. Bacterial LPS is recognized by TLR3. " " TLRs act as an alarm system to alert both the innate and adaptive immune systems that an infection is brewing. " " Cytokines released by activated macrophages increase permeability of blood vessels. " " Acute phase proteins are produced by activated macrophages. " " TNF-alpha may be released systemically. "arrow_forward
- Johnny has just been infected and needs your help in letting him know how his body is fighting the infection. To do so, describe how the innate and adaptive immune systems work together. You should address the following: 1. define adaptive and innate immunity; 2. Describe the role of natural killer cells (how do they work); 3. what are antigen presenting cells and what is their function, what are MHCs?; 4. describe the role of the complement system; 5. what is the role of interferons?; 6. How do helper T cells, cytotoxic T cells and B lymphocytes work make sure you address adaptive immunity memory?; 7. Define HIV, which cells do they attack and why do some individuals develop persistent lymphadenopathy (swollen or enlarged lymph nodes)?arrow_forwardNew Skin' research center uses mice for studies of skin grafting. To prevent rejection of the graft, the mice are thymectomized (taking out thymus) at birth. Even though B cells do not develop in the thymus, these mice show no humoral immune response and are very susceptible to infection. Explain why the removal of the thymus would improve the success of skin grafts but adversely affect humoral immunity.arrow_forwardThe selection process for T cells is more complex than B cells. Please explain the process, why it is more complex, and how/why autoreactive T cells are allowed to leave the thymus.arrow_forward
- Mention the site in the body where the B-cells and T-cells are formed. Give one difference between them.arrow_forward________and ________are part of the adaptive immune system and able to establish immunological memory. These mark pathogens for destruction by phagocytes and complement proteins, and neutralize pathogens so they cannot attach to cells. Group of answer choices B-cells T-cells Antigen presenting cells Antibodies Cytokinesarrow_forwardCHAPTER 20 The Lymphatic System and Immunity Matching SECTION 3 Revie w Match each lettered term with the most closely related description. a. opsonization 1 b. helper T cells Two parallel pairs of polypeptide chains Found on helper T cells C. antibody d. class II MHC 3 Active and passive 4 Transfer of antibodies e. costimulation Attacked by HIV f. IgM 6 Enhances phagocytosis g. class I MHC h. IgG 7 MHC proteins present in the plasma membranes of all nucleated cells i. passive immunity j. anaphylaxis 8 Differentiate into memory and plasma cells 9 MHC proteins present in the plasma membranes of all APCS and lymphocytes 9 k. CD4 markers 10 I. acquired immunity 10 Antibodies used to determine blood type 11 m. B lymphocytes 11 Secondary binding process required for T cell activation 12 12 Accounts for 80 percent of all immunoglobulins 13 13 Circulating allergen stimulates mast cells throughout body Match each lettered term with thearrow_forward
- Which of the following is TRUE regarding Gram negative bacteria? a- Their cell wall is composed of a large proportion of sugars b- Their cell wall does not absorb the Gram stain and turns pink c- Their cell wall is composed of a small proportion of peptidoglycan d- Two of the above statements are true Which T-lymphocytes activate the B-cell response? 1- suppressor T-cells. 2- cytotoxic T-cells. 3- helper T-cells. 4- memory T-cells. Substances that are injected containing an antigen to stimulate the immune system to respond are called a- antibodies b- medications. c- vaccines d- antibioticsarrow_forwardDescribe HOW the spike protein produced by your own cells results in an immune response, antibody production and memory! You will need to mention the cell receptors involved, the specific T-cells and "other" lymphocytes that are part of this process and explain how all of this leads to antibody production and circulation for three months. Need answer in short but ASAPLYarrow_forwardWith the aid of a hand drawn diagram, briefly explain how T cells are primed or activated by B cells. In your response, briefly outline the major differences between B and T cell activationarrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage Learning
Biology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStax
Human Heredity: Principles and Issues (MindTap Co...
Biology
ISBN:9781305251052
Author:Michael Cummings
Publisher:Cengage Learning
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax