Biochemistry
Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Chapter 13, Problem 22P
Interpretation Introduction

(a)

Interpretation:

The factor by which an open to closed ratio increases by the binding of the firstacetylcholine molecule and the second acetylcholine molecule needs to be explained.

Concept introduction:

Acetylcholine act as a neurotransmitter which means, it sends messages or chemicals from one cell to another cell of the body. Acetylcholinesterase helps in stopping the excitation of a nerve cell after the transmission of impulse. In other words, this enzyme causes rapid hydrolysis of acetylcholine.

Interpretation Introduction

(b)

Interpretation:

The corresponding free energy contribution of the channel at 250C needs to be determined.

Concept introduction:

Acetylcholine act as a neurotransmitter which means it sends messages or chemicals from one cell to another cell of the body. Acetylcholinesterase helps in stopping the excitation of a nerve cell after the transmission of impulse or in other words, we can say that this enzyme causes rapid hydrolysis of acetylcholine.

Interpretation Introduction

(c)

Interpretation:

Whether the allosteric transition be accounted for the MWC concerted mode or not needs to be explained.

Concept introduction:

Acetylcholine acts as a neurotransmitter which means, it sends messages or chemicals from one cell to another cell of the body. Acetylcholinesterase helps in stopping the excitation of a nerve cell after the transmission of impulse or in other words, one can say that this enzyme causes rapid hydrolysis of acetylcholine.

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