You are presented with the following clinical scenario: "A 12 month old male child presents with recurrent bacterial infections. Flow cytometry shows a complete lack of B- lymphocytes." Using your knowledge of immunology and flow cytometry, identify which dot plots represent the healthy control and patient samples in each scenario and come up with a clinical diagnosis. Note that you may need to use additional background sources to fully understand what is going on at the cellular level for each diagnosis. What is the clinical diagnosis O HIV/AIDS O COVID-19 O LAD type 1 CD4-FITC CD8-PE CD45-PE CD8-PE 70% 13% 52% 10% 82% 27% 5% CD8-PE CD4-FITC CD20-FITC CD4-FITC 17% 38% 13% 68% Agammaglobulinaemia CD45-PE CD4-FITC CD45-PE CD45-PE 35% 8% 93% 22% CD15-FITC CD8-PE CD20-FITC CD15-FITC Select the flow cytometry dot plot that corresponds to the healthy control sample Select the flow cytometry dot plot that corresponds to the patient sample 30% 0% 77%

You are presented with the following clinical scenario: "A 12 month old male child presents with recurrent bacterial infections. Flow cytometry shows a complete lack of B- lymphocytes." Using your knowledge of immunology and flow cytometry, identify which dot plots represent the healthy control and patient samples in each scenario and come up with a clinical diagnosis. Note that you may need to use additional background sources to fully understand what is going on at the cellular level for each diagnosis. What is the clinical diagnosis O HIV/AIDS O COVID-19 O LAD type 1 CD4-FITC CD8-PE CD45-PE CD8-PE 70% 13% 52% 10% 82% 27% 5% CD8-PE CD4-FITC CD20-FITC CD4-FITC 17% 38% 13% 68% Agammaglobulinaemia CD45-PE CD4-FITC CD45-PE CD45-PE 35% 8% 93% 22% CD15-FITC CD8-PE CD20-FITC CD15-FITC Select the flow cytometry dot plot that corresponds to the healthy control sample Select the flow cytometry dot plot that corresponds to the patient sample 30% 0% 77%

An Illustrated Guide To Vet Med Term

4th Edition

ISBN:9781305465763

Author:ROMICH

Publisher:ROMICH

Chapter15: Feed And Protect Me

Section: Chapter Questions

Problem 1CP

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Select the flow cytometry dot plot that corresponds to the healthy control sample Select the flow cytometry dot plot that corresponds to the patient sample
As a perinatal Nurse, you must discuss the results of Parvovirus B19 antibody testing with your 22-year old patient. The patient is pregnant and has a high Parvovirus IgM titer. What does the high IgM titer indicate? (1 or 2 words) What does it mean if the patient above had high IgG and low IgM titers? (2 or 3 words)
Please explain, would the answer be C). This patient is at risk for infection because of his low white blood cell count. 64-year-old African American male visits his primary care physician with complaints of bone pain, fatigue, nausea, loss of appetite, and constipation. The patient has a history of good health and exercises regularly. However, his recent symptoms have started to interfere with his active lifestyle. After a physical examination, his physician orders laboratory analysis to identify what might be causing his symptoms. Based on the CBC results and your knowledge of the cellular components of the immune system, what is an immunological concern for this patient? A). This patient is at increased risk for bruising and bleeding because of his low platelet count. B). The patient’s fatigue is caused by the lack of red blood cells (anemia). C). This patient is at risk for infection because of his low white blood cell count.
Case scenario A 19-year-old male visits his primary care physician with a sore throat, swollen lymph nodes, and extreme fatigue. During the visit, the nurse finds that he has a fever. The patient reports that he is attending his second year of college at a local university. The physician performs a physical examination, which confirms large, swollen, painful lymph nodes. He decides to send the patient to the office laboratory for blood work. He orders a complete blood count (CBC) and viral and bacterial studies. Question: 1. Based on the information obtained thus far, what does the laboratory analysis indicate? Explain your answer. 2. The patient's symptoms of fever and painful, swollen lymph nodes are caused by what innate immune mechanisms? Explain your answer 3. About 50% of patients with chronic viral infection develop splenomegaly. Based on what you know about the organs of the immune system, why would this condition develop?
When a patient exhibits a four-fold or greater rise in antibody titer against a specific microbial antigen between acute-phase and convalescent-phase serum samples, this is considered to be a “seroconversion”. Which of the following would be a correct interpretation of a seroconversion? what option below is the answer? None of the other four answers are a correct interpretation of a seroconversion These results show that the microbe itself has been detected in the patient’s sample(s) These findings cannot be interpreted because antibodies aren’t specific enough for antigens There is no evidence of current active infection because that would require that the antibody titer is decreasing rather than increasing The results show evidence of current or recent infection by the specific microbe because there has been an active immunologic response to its antigen
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A 18 month-old child is found to have measles antibodies in his blood. Suggest 3 different ways how the child could have acquired such antibodies 2. Describe what usually happens in a phagocytic vesicle after a phagocyte has engulfed a bacterium (diagrams maybe used but not required):
When a patient exhibits a four-fold or greater rise in antibody titer against a specific microbial antigen between acute-phase and convalescent-phase serum samples, this is considered to be a "seroconversion". Which of the following would be a correct interpretation of a seroconversion? None of the other four answers are a correct interpretation of a seroconversion These findings cannot be interpreted because antibodies aren't specific enough for antigens There is no evidence of current active infection because that would require that the antibody titer is decreasing rather than increasing These results show that the microbe itself has been detected in the patient's sample(s) The results show evidence of current or recent infection by the specific microbe because there has been an active immunologic response to its antigen
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A lab tech was rushed to the ER after a needlestick injury due to improper needle disposal. A Hepatitis Panel was ordered and the results were as follows: A Hepatitis Panel was ordered, and the results were as follows:HBsAg: negativeAnti- HBc (IgM): negativeAnti-HBc: negativeAnti-HBs: positiveAnti-HCV: negative Question: What is the test(s) used to indicate current Hep B infection?
asap Which of the following would not be consistent with Infectious Mononucleosis (IM): a Absolute Lymphocyte count of <4.0 x 109/L b Relative Lymphocyte count usually >50% c Greater than 20% reactive lymphocytes counted on manual differential d Positive heterophile antibody test.
A laboratory scientist working in the hematology department receives a patient sample for a CBC. The scientist checks the sample for clots and mixes the tube well. They place the tube on the instruments and await the results. The results indicate that there are elevated numbers of white blood cells, with a large majority of lymphocytes. This resulted in the addition of a differential examination. The lab scientist then prepares a stained peripheral push smear for differential review. Once dry, the slide is placed on the microscope for review. When scanning with 10x objective, the lab scientist finds the feathered edge and changes to an objective with higher magnification. On higher magnification the lab scientist has difficulty finding a clear view. The view is foggy and lacks resolution. When the scientist checks the sample of clots and mixes the tube before testing, they are checking for what kind of variable that could have an effect on testing? The laboratory scientist…