Write T if the statement is correct; write F if the statement is not correct. Antigen fragments that bind to MHC class I molecules are typically in endosomes. " " TAP1 and TAP2 are present on the plasma membrane of APCs. " " Proteasomes process antigens within the endoplasmic reticulum. " " Newly synthesized MHC class I molecules can be found within endosomes. " " Newly synthesized MHC class I α chains assemble in the ER with calnexin. " "

Write T if the statement is correct; write F if the statement is not correct. Antigen fragments that bind to MHC class I molecules are typically in endosomes. " " TAP1 and TAP2 are present on the plasma membrane of APCs. " " Proteasomes process antigens within the endoplasmic reticulum. " " Newly synthesized MHC class I molecules can be found within endosomes. " " Newly synthesized MHC class I α chains assemble in the ER with calnexin. " "

Biology 2e

2nd Edition

ISBN:9781947172517

Author:Matthew Douglas, Jung Choi, Mary Ann Clark

Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark

Chapter42: The Immune System

Section: Chapter Questions

Problem 1VCQ: Figure 42.11 Which of the following statements about T cells is false? Helper T cells release...

See similar textbooks

Similar questions

Write T if the statement is correct; write F if the statement is not correct. Interferons enhance antigen presentation. " " Peptides that bind to MHC class II molecules are longer than those that bind MHC class I molecules. " " MHC molecules that lack a bound peptide is unstable. " " MHC class I:peptide:TCRcomplexes and MHC class II:peptide:TCR complex shows very similar orientation. " " The Golgi apparatus is part of the endomembrane system. " "
Indicate whether each of the cell components or processes given is involved the processing and presentation of exogenous antigens, endogenous antigens, or both. (Assume n cross-presentation here.) Exognenous Both Possible answers proteasomes MHC class II molecules No Answers Chosen No Answers Chosen phagocytosis or endocytosis invariant chains calnexin tapasin Endogenous No Answers Chosen vesicular transport from RER to Golgi lysosomal hydrolases TAP1 and TAP2 proteins MHC class I molecules
Write T if the statement is correct; write F if the statement is not correct. P and E selectins are expressed by endothelial cells. " " TCRs consist of heavy and light chains. " " A disulfide bond can be found on TCRs. " " The antigen binding site in TCRs is contributed by the variable region of the H chain and the variable region of the light chain. " " CD4, but not CD8, interacts with Lck. " "
Which of the following statements is NOT correct? Group of answer choices -Natural killer cells are cytolytic lymphocytes that mediate ADCC -Neutrophils carry out phagocytosis of C3b-tagged particles -Macrophages carry out phagocytosis of C3b-tagged particles -Mast cells produce granules containing the cytotoxin perforin -B lymphocytes express a receptor for complement proteins
Identify the cells that display MHC class I and MHC class IIproteins on their surfaces
The cytokine that activates macrophages, inhibits viral replication, and increases MHC Class I expression is interferon. True False
Why would a virus that can interfere with a host cell’s production of MHC class I molecules be at an advantage?
You are working in a hospital and saw a patient who has rashes on his body, conjunctivitis, facial paralysis, and a swollen knee. Since you just learned about lymphocytes and the MHC classes in Dr. Starnges lecture, what MHC class and lymphocyte will work together to remove the infection? As we know all the lymphocytes that recognize self peptides are eliminated by immune system but why, after treatment with antibiotic, did the patient develop chronic arthritis?
The virus shown in the diagram below is only able to infect and replicate in epithelial cells. In order for the cross-presenting dendritic cell to display viral peptides, rather than self peptides on its surface MHC class I proteins, which of the following procedures could be utilized, starting with the components shown in the figure below? Mix epithelial cells with heat-killed virus, wait 24 hrs, wash away any virus particles outside the epithelial cells, then add epithelial cells to dendritic cells. Mix epithelial cells with viral peptides, wait 24 hrs, wash away any viral peptides not bound to the epithelial cells, then add epithelial cells to dendritic cells. Mix epithelial cells with live virus particles, wait 24 hrs, wash away any virus particles outside the epithelial cells, then add epithelial cells to dendritic cells. Mix dendritic cells with viral nucleic acids and epithelial cells for 24 hrs. MIx epithelial cells will viral nucleic acids, wait 24 hrs, wash away any viral…
Write T if the statement is correct; write F if the statement is not correct. Bacterial LPS is recognized by TLR3. " " TLRs act as an alarm system to alert both the innate and adaptive immune systems that an infection is brewing. " " Cytokines released by activated macrophages increase permeability of blood vessels. " " Acute phase proteins are produced by activated macrophages. " " TNF-alpha may be released systemically. "
Which statement is true? Class I MHCs display exogenous antigen and are present on all nucleated cells. Class II MHCs display exogenous antigen and are present on antigen presenting cells. Class I MCHs display endogenous antigen and are present on antigen presenting cells. Class II MCHs display endogenous antigen and are present on all nucleated cells.
MHC class I proteins: A. both are on all nucleated cells and present endogenous antigens to the immune system B. present endogenous antigens to the immune system C. are on all nucleated cells