Write out the steps needed to synthesize the following peptide using the Merrifield method.

Organic Chemistry: A Guided Inquiry
2nd Edition
ISBN:9780618974122
Author:Andrei Straumanis
Publisher:Andrei Straumanis
Chapter24: Carboxylic Acids & Derivatives
Section: Chapter Questions
Problem 25E
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Write out the steps needed to synthesize the following peptide using the Merrifield method.

Expert Solution
Step 1

Merrifield Method:

In this method, the peptide is being produced by the removal of water from the C terminus chain of the amino acid to the other chain of amino acid in the presence of the compound N,N'-Dicyclohexylcarbodiimide (DCC) or either from the esterification of the amino acids.

Step 2

The steps for the synthesis of the following peptide are:

 

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