The sequence shown below is an actual sequence of the toxin gene from Salmonella enterica subspecies serovar Typhimurium strain obtained from the NCBI database. ATGCGAACCTTCAAAACCAGGTGGTTTAACAGAGAAGCGAAGCCCCACACGATAAAAGATGACGAGTTAA GCGAGGCCATCAACGCCGTACTGCAAGGAAAAGCAGATAATCTTGGCGGCGGGGTTTATAAAAAACGTCT CAATCAAAATCGCGATCGCGCAATCGTGTTGGCAAAGGGAGGCGAACATTGGTTTTACACCTTCCTGTAT GCCAAACAGGATATGGCCAACATTAGCTATCGCGAACTCGCGGGTTTCCGTGAGTTAGCAAAACACTATG CTTGCCTGACCGAAGATCAGATAACGGCACTCATTAATAACAAAGAACTGGTAGAGGTGCGCCATGTCAG CAAAAACTAA (i) Is the nucleotide sequence above translatable into a complete protein? Give justification. (ii) Is the sequence above represented in the standard FASTA format? Explain your answer. (iii) Liliana, a research officer would like to perform a multiple sequence alignment between the sequence above with eight other toxin genes sequences obtained from other researchers. Define multiple sequence alignment. (iv) Which multiple sequence alignment program would you recommend to Liliana for the comparison of the toxin sequence above with other toxin genes from other organisms?

The sequence shown below is an actual sequence of the toxin gene from Salmonella enterica subspecies serovar Typhimurium strain obtained from the NCBI database. ATGCGAACCTTCAAAACCAGGTGGTTTAACAGAGAAGCGAAGCCCCACACGATAAAAGATGACGAGTTAA GCGAGGCCATCAACGCCGTACTGCAAGGAAAAGCAGATAATCTTGGCGGCGGGGTTTATAAAAAACGTCT CAATCAAAATCGCGATCGCGCAATCGTGTTGGCAAAGGGAGGCGAACATTGGTTTTACACCTTCCTGTAT GCCAAACAGGATATGGCCAACATTAGCTATCGCGAACTCGCGGGTTTCCGTGAGTTAGCAAAACACTATG CTTGCCTGACCGAAGATCAGATAACGGCACTCATTAATAACAAAGAACTGGTAGAGGTGCGCCATGTCAG CAAAAACTAA (i) Is the nucleotide sequence above translatable into a complete protein? Give justification. (ii) Is the sequence above represented in the standard FASTA format? Explain your answer. (iii) Liliana, a research officer would like to perform a multiple sequence alignment between the sequence above with eight other toxin genes sequences obtained from other researchers. Define multiple sequence alignment. (iv) Which multiple sequence alignment program would you recommend to Liliana for the comparison of the toxin sequence above with other toxin genes from other organisms?

Biology: The Dynamic Science (MindTap Course List)

4th Edition

ISBN:9781305389892

Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Chapter19: Genomes And Proteomes

Section: Chapter Questions

Problem 1ITD: Below is a sequence of 540 bases from a genome. What information would you use to find the...

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The FDA finds that chickens across the US are infected with a new type of bird-flu. They determine the sequence coding for the virus's surface proteins and see that some chickens' viruses have code (1) and some chickens' viruses have code (II). (1) 5' CAUGAUAUUGUACUUU 3' (II) 5' GAAUGGAACUGCAACUC 3' nal Translate the partial sequence for type I flu protein. "Be sure to start translation at the start codon! Second letter U C G UUU Phe UUC. UUA UUG FLeu UCU UCC Ser UAU UAC Tyr UGCJoys UAA Stop UGA Stop UAG Stop UGG Trp G UCA UCG CUU CCU CC CA CCG CAU His CACJ Pro CAA1 GIin CAGJ CGU) CGC CUC Leu CUA CGA Arg CGG CUG ACU ACC ACA AUG Met ACG AAU AACJ AAA AAGJ AGU Ser AGC. AUU Asn AUC le Thr AUA AGA Arg Lys AGG. GUU GUC Val G GUA GUG GCU GCC GCA GCG GGU) GGC GAU Asp GAC. Ala GAA) Glu GAGJ GGA Gly GGG O Glu - Trp - Asn - Cys - Asn O Met - Glu - Leu - Gin - Leu O Met - lle - Val - Leu - Gly O Met - lle - Leu - Tyr - Phe O His - Asp - lle - Val - Leu First letter Third letter
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