Sulfonation of alcohols to form mesylates, tosylates, or triflates turns the ordinarily poor alcohol-leaving group into a good resonance- stabilized leaving group. Consider the synthetic scheme below, which involves a sulfonation, and predict the product of the two-step sequence. :.... : OH 1. MsCl 2. (CH3)3CONa

Sulfonation of alcohols to form mesylates, tosylates, or triflates turns the ordinarily poor alcohol-leaving group into a good resonance- stabilized leaving group. Consider the synthetic scheme below, which involves a sulfonation, and predict the product of the two-step sequence. :.... : OH 1. MsCl 2. (CH3)3CONa

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter10: Alcohols

Section: Chapter Questions

Problem 10.52P: Alcohols are important for organic synthesis, especially in situations involving alkenes. The...

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