Relative Relative H3/H4 Acetylation Relative H3 Acetylation H4 Acetylation DON -4Kb -3Kb -2Kb -1Kb +1 Insulin You are studying histone modification at the insulin gene in cell types that express insulin (3 & A 4) compared to cell types that do not express insulin (1 & 2). Enhancer Promoter 20 15 10 5 Discuss with your pod: In which cell type(s) is H3 acetylation highest? In which cell type(s) is H4 acetylation highest? 3. Is histone acetylation the same at the enhancer and promoter? 4. Based on the data, which histone modification is most 1. В 20 2. 15 10 5 C important for activating insulin gene expression?
Relative Relative H3/H4 Acetylation Relative H3 Acetylation H4 Acetylation DON -4Kb -3Kb -2Kb -1Kb +1 Insulin You are studying histone modification at the insulin gene in cell types that express insulin (3 & A 4) compared to cell types that do not express insulin (1 & 2). Enhancer Promoter 20 15 10 5 Discuss with your pod: In which cell type(s) is H3 acetylation highest? In which cell type(s) is H4 acetylation highest? 3. Is histone acetylation the same at the enhancer and promoter? 4. Based on the data, which histone modification is most 1. В 20 2. 15 10 5 C important for activating insulin gene expression?
Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter32: The Reception And Transmission Of Extracellular Information
Section: Chapter Questions
Problem 21P
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