Homework Help is Here – Start Your Trial Now!
Science
Biochemistry
Question: Estimate the pl of the tripeptide ? Step 1: Determine what can be protonated/deprotonated Step 2: Estimate where the net charge of the protein would be = 0 Step 3: Use the pka's that bracket the neutral form. +H₂N H H H соон сно CH₂ coo- CH3 CH₂ COO H3N pka= 9.82 pka= 3.86 O O=C H H H H CH3 CH3 COO pka= 2.19

Question: Estimate the pl of the tripeptide ? Step 1: Determine what can be protonated/deprotonated Step 2: Estimate where the net charge of the protein would be = 0 Step 3: Use the pka's that bracket the neutral form. +H₂N H H H соон сно CH₂ coo- CH3 CH₂ COO H3N pka= 9.82 pka= 3.86 O O=C H H H H CH3 CH3 COO pka= 2.19

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
See similar textbooks
icon
Related questions
Question
Question: Estimate the pl of the tripeptide ? Step 1: Determine what can be protonated/deprotonated Abundance Step 2: Estimate where the net charge of the protein would be = 0 Step 3: Use the pka's that bracket the neutral form. +H₂N COOH تیار کیا ہے CH₂ H CC H +1 H₂N H COOH CH3 CH3 0 1 2 cook CH₂ coof H pkg= 2.19 O H H₂N No charge H H соон CH3 CH3 3 4 pka= 3.86 Coo COO™ CH₂ H H H coof CH3 CH3 pka= 4.25 COO - 2 5 6 6 Coo J. CH₂ 7 pH O H H 8 H coo- CH3 CH3 COO" 9 + Н. H3N pka= 9.82 10 pka= 9.82 pka= 3.86 CH₂ H₂N 11 H H H coo CH₂ p - 3 O=C H H H 12 H pka= 4.25 O CH3 1 CH3 coo- CH3 CH3 COO 13 COO pka= 2.19 coo 14
Transcribed Image Text:Question: Estimate the pl of the tripeptide ? Step 1: Determine what can be protonated/deprotonated Abundance Step 2: Estimate where the net charge of the protein would be = 0 Step 3: Use the pka's that bracket the neutral form. +H₂N COOH تیار کیا ہے CH₂ H CC H +1 H₂N H COOH CH3 CH3 0 1 2 cook CH₂ coof H pkg= 2.19 O H H₂N No charge H H соон CH3 CH3 3 4 pka= 3.86 Coo COO™ CH₂ H H H coof CH3 CH3 pka= 4.25 COO - 2 5 6 6 Coo J. CH₂ 7 pH O H H 8 H coo- CH3 CH3 COO" 9 + Н. H3N pka= 9.82 10 pka= 9.82 pka= 3.86 CH₂ H₂N 11 H H H coo CH₂ p - 3 O=C H H H 12 H pka= 4.25 O CH3 1 CH3 coo- CH3 CH3 COO 13 COO pka= 2.19 coo 14
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 3 steps with 6 images

SEE SOLUTIONCheck out a sample Q&A here
Blurred answer
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781319114671
Author:
Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:
W. H. Freeman
Lehninger Principles of Biochemistry
Lehninger Principles of Biochemistry
Biochemistry
ISBN:
9781464126116
Author:
David L. Nelson, Michael M. Cox
Publisher:
W. H. Freeman
Fundamentals of Biochemistry: Life at the Molecul…
Fundamentals of Biochemistry: Life at the Molecul…
Biochemistry
ISBN:
9781118918401
Author:
Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:
WILEY
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305961135
Author:
Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:
Cengage Learning
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305577206
Author:
Reginald H. Garrett, Charles M. Grisham
Publisher:
Cengage Learning
Fundamentals of General, Organic, and Biological …
Fundamentals of General, Organic, and Biological …
Biochemistry
ISBN:
9780134015187
Author:
John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher:
PEARSON
SEE MORE TEXTBOOKS