Isozymes: d) One way of regulating metabolic pathways is through isozymes. What is an isozyme? e) Provide a concrete example of an isozyme from carbohydrate metabolism. f) From your chosen isozyme in part b), describe how it is regulated differently in various cells.
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- Acetyl COA (ACC) is a critically important molecule in metabolic pathways. This molecule can be used for gluconeogenesis or fatty acid synthesis. It can also proceed through the TCA cycle to generate energy. Which of these molecules would be a negative allosteric regulator of ACC? A) citrate ACC is allosterically regulated. B) ATP C) palmitoyl COA D) glucose E) acetyl COAWhich of the following statements regarding catabolism and anabolism is incorrect? a) All metabolic reactions give off energy as their by-product. b) Synthesis of polysaccharides from monosaccharides is an example of anabolic process. c) Hydrolysis of oligosaccharides to monosaccharides is an example of catabolic process. d) Some, but not all, metabolic reactions involve catabolism.Which of the following is an important end product of disassembly of fatty acids? answer choices A.) DNA gyrase B.) Pyruvate C.) Acetyl CoA D.) Succinate dehydrogenase
- The fats metabolic pathway represented above corresponds to lipolysis (i.e., oxidation of fatty acids) and is a… Question 5 options: a) Catabolic pathway. b) Anabolic pathway. c) Both a catabolic and an anabolic pathway. d) Allosteric pathway. e) None of the above.Which of the following statement regarding coenzyme A is incorrect? a) The B vitamin pantothenic acid is present as a subunit of its structure. b) Its main biochemical function is to transfer acetyl groups. c) Its structure contains a phosphorylated ADP.. d) The B vitamin pantothenic acid is the “active” subunit of the coenzyme A.Phosphofructokinase catalyzes the conversion of ... A) oxaloacetate to citrate OB) glucose to fructose 6-phosphate C) fructose 6-phosphate to fructose 1,6-bisphosphate D) pyruvate to acetyl CoA E) a phosphorylated 6-carbon sugar to two 3-carbon sugars
- complex allosteric regulation of the aspartate transcarbamoylase reaction is significant because it links? a) citric acid cycle and catecholamine biosynthesis b)glycolysis and lactic acid fermentation c) opiate with neurotransmitter d) glycolysis and fatty acid metabolism e) amino acid and nitrogenous base metabolismIn the metabolic pathway, A->B->C->D->E what effect would molecule E likely have on the enzyme that catalyzes A->B? (The answer is A. Could you justify the reason why the answer is A?) a) Allosteric inhibitor b)Allosteric activator c) Competitive inhibitor d) feedback activator e) coenzymeWhich of the following describes a purpose for the function of phosphoglucoisomerase? a) allows for phosphorylation for trapping the molecule in the cell b)promotes substrate level phosphorylation and formation of ATP c) allows formation of a primary alcohol necessary for the next step of phosphorylation d)facilitates epimerization, the change in stereochemistry at one chiral carbon
- The major control enzyme in glycolysis is: a) hexokinase b) phosphofructokinase c) aldolase d) pyruvate kinase In step 4, when fructose-1,6-biphosphate is cleaved, the two molecules formed are: a) GAP and DHAP b) GAP and 3-PG c) 3-PG and 2-PG d) PEP and pyruvate NAD is used in which step? A) conversion of DHAP to GAP b) conversion of GAP to 1,3-BPG c) conversion of 1,3-BPG to 3-PG d) conversion of PEP to pyrunate The number of ATP molecules formed at the substrate level in glycolysis is: a) 1 B) 2 c) 3 d) 5 The number of ATP molecules formed indirectly via oxidative phosphorylation in glycolysis is: a) 1 B) 2 c) 3 d) 5If a slight deficiency in the Vitamin B1 derivative Thiamine Pyrophosphate (TPP) leads to an accumulation of substrates for reactions utilizing this cofactor, A) what substrates would ‘accumulate’ in a human after eating a an enormous amount of sugar-laden Halloween candy, AND what would be the regulatory consequences on carbohydrate metabolism? B) what substrates would accumulate in yeast cells cultured under anaerobic (no oxygen) conditions AND what would be the regulatory consequences on carbohydrate metabolism? C) and lastly, what substrates would accumulate in plant cells incorporating carbon and generating energy solely using photosynthesis?If a slight deficiency in the Vitamin B1 derivative Thiamine Pyrophosphate (TPP) leads to an accumulation of substrates for reactions utilizing this cofactor, A) what substrates would ‘accumulate’ in a human after eating a an enormous amount of sugar-laden Halloween candy, AND what would be the regulatory consequences on carbohydrate metabolism? B) What substrates would accumulate in yeast cells cultured under anaerobic (no oxygen) conditions AND what would be the regulatory consequences on carbohydrate metabolism? C) What substrates would accumulate in plant cells incorporating carbon and generating energy solely using photosynthesis?