"In most differentiated tissues, daughter cells retain a memory of gene expression patterns that were present in the parent cell through mechanisms that do not involve changes in the sequence of their genomic DNA" is true or false.

"In most differentiated tissues, daughter cells retain a memory of gene expression patterns that were present in the parent cell through mechanisms that do not involve changes in the sequence of their genomic DNA" is true or false.

Name: "In most differentiated tissues, daughter cells retain a memory of gen
Uploaded: 2024-03-20T06:42:41.000Z
Channel: Bartleby
Description: "In most differentiated tissues, daughter cells retain a memory of gene expression patterns that were present in the parent cell through mechanisms that do not involve changes in the sequence of their genomic DNA" is true or false.

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter12: Genes And Cancer

Section: Chapter Questions

Problem 15QP: Which of the following mutations will result in cancer? a. homozygous recessive mutation in a...

See similar textbooks

Similar questions

"once cells have differentiated to their final specialized forms, they never again alter expression of their genes" is true or false.
List the following steps of gene expression in eukaryotes in chronological order. Also indicate which events take place in the nucleus and which take place in the cytoplasm. RNA processing, transcription, translation, RNA breakdown into nucleotides
Twist transcription factors (TF) play key roles in embryonic development and are largelyundetectable in normal adult tissues; however, their expression is reactivated during tumorprogression and correlates with invasive and metastatic lesions. Transcription of the Twistgene is activated by Wnt signals and the Twist TF represses the gene for E-cadherin.Answer the following questions as briefly as possible, based on what was presented in class,not an internet search (complex answers that go beyond class material may lose points)a. Outline the steps from the Wnt signal to the E-cadherin gene (inclusive);e.g., A → B → C (with some clarifications such as “binds to”, “activates”, “represses”)b. What are the normal cellular and embryonic (morphological) consequences of Twist expression?c. How would inappropriate expression contribute to cancer?
D) The level of carbon dioxide increases with the level of available oxygen. 60) The TP53 gene provides instructions for making a protein called tumor protein p53. Known as the guardian of the genome, this protein acts as a tumor suppressor, which means that it regulates cell division by keeping cells from growing and dividing too fast or in an uncontrolled way. The p53 protein is located in the nucleus of cells throughout the body, where it attaches directly to DNA and plays a critical role in determining whether the DNA will be repaired or the damaged cell will self- destruct (undergo apoptosis). If the DNA can be repaired, p53 activates other genes to fix the damage. If the DNA cannot be repaired, this protein prevents the cell from dividing and signals it to undergo apoptosis. eg Suppose chromosomes in a skin cell are damaged by ultraviolet radiation. If the damaged genes do not affect p53, which choice correctly predict if the cell will become cancerous and why? No, the cell will…
MSH2 is a gene commonly associated with HNPCC (Hereditary nonpolyposis colorectal cancer). This gene encodes a protein that is involved in mismatch repair. Why are individuals who are heterozygous for the deletion mutation of MSH2 gene (MSH2+/MSH2-) from birth are very likely to develop colon cancer very early in their lives?
D) The level of carbon dioxide increases with the level of available oxygen. 60) The TPS3 gene provides instructions for making a protein called tumor protein p53. Known as the guardlan of the genome, this protein acts as a tumor suppressor, which means that it regulates cell division by keeping cells from growing and dividing t0o fast or in an uncontrolled way. The p53 protein is located in the nucleus of cells throughout the body, where it attaches directly to DNA and plays a critical role in determining whether the DNA will be repaired or the damaged cell will self- destruct (undergo apoptosis). If the DNA can be repaired, p53 activates other genes to fix the damage. If the DNA cannot be repaired, this protein prevents the cell from dividing and signals it to undergo apoptosis. Suppose chromosomes in a skin cell are damaged by ultraviolet radiation. If the damaged genes do not affect p53, which choice correctly predict if the cell will become cancerous and why? No, the cell will not…
Explain how the same gen can be highly expressed in several distinct tissues (e.g. brain, liver, and lung) of an organism, yet silent in all other tissues. Hint: The answer is not that they share the same tissue-specific transcription factors..
Describe how mutations in genome maintenance factors promote tumorigenesis. Why would inactivation of a mis- match repair gene cause colon cancer?
Acquired mutation in the p53 gene is the most common genetic alteration found in human cancer (> 50% of all cancers). A germline mutation in p53 is the causative lesion of Li- Fraumeni familial cancer syndrome. In many tumors, one p53 allele on chromosome 17p is deleted and the other is mutated. What type of protein is encoded by the p53 gene? (A) Caspase (B) DNA repair enzyme (C) Membrane cell adhesion molecule (D) Serine phosphatase (E) Telomerase (F) Transcription factor (G) Tyrosine kinase
Describe the steps by which the TP53 gene responds to DNA damage and/or cellular stress to promote cell-cycle arrest and apoptosis. Given that TP53 is a recessive gene and is not located on the X chromosome, why would people who inherit just one mutant copy of a recessive tumor-suppressor gene be at higher risk of developing cancer than those without the recessive gene?
Long non-coding RNAs (lncRNA) can act as a scaffold to form protein/RNA complexes that regulate gene expression? True False Wnt is a regulatory factor that regulate myogenic stem cell proliferation? True False
"In the cellular regulatory pathways that control cell growth and proliferation, the products of oncogenes are stimulatory components and the products of tumor suppressor genes are inhibitory components" is true or false.