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Q: 979
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A: The right option is : None of them
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Q: Which of the following physical traits are associated with Down syndrome? Check All That Apply short…
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Q: How many total sister chromatids would be present a human cell for the following? 1) Mitosis,…
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Explain what gene mapping is and discuss any three methods used to interpret
gene maps. please expain brifly with examples
Step by step
Solved in 3 steps
- Discuss the principles underlying genetic linkage and recombination, and the use of these in gene mapping.Briefly describe the steps or methods for studying genes. Start with targeting a gene region and end with gel electrophoresis. How does using gel electrophoresis help to determine the genotypes of individuals?What is a molecular marker? Give two examples. Discuss why it isgenerally easier to locate and map molecular markers rather thanfunctional genes.
- You would like to isolate loci in the genome that influence plant height in tomato plants. Describe how you would achieve this through QTL mapping. Choose a true breeding tall strain and a true breeding short strain and compare the genomic sequences. Choose a true breeding tall strain and true breeding short strain and type them for molecular markers. Mate them together to produce F1 offspring and evaluate whether the F1 are tall or short. Choose two true breeding tall strains and compare the genomic sequences. Choose a true breeding tall strain and true breeding short strain and type them for molecular markers. Mate them together to produce F1 offspring. Genotype the F1 to identify makers that are associated with differences in plant height. Choose a true breeding tall strain and true breeding short strain and type them for molecular markers. Mate them together to produce F1 offspring, then backeross the F1 offspring to produce F2 offspring carrying recombinant chromosomes from tall…Describe why genetic mapping is useful?List three clinical indications for chromosome and/or genome analysis and why the process might be important for each indication.
- What provides a convenient bridge between the low resolution of a karyotype and the ultra-high resolution of a complete genomic sequence?ISSR is generally a dominant STS DNA marker. Nonetheless, with validated experimental evidence (e.g. laboratory and population genetics data), the marker can be used in codominance marker genotyping. Briefly explain each case below: a) Codominant marker targets specific locus and reveals allelic variations in that locus among DNA samples. b) Dominant marker: primers can complement other repeat sequences or in multiple loci thereby non-specificity in sampled genomes.Bioinformatics is an interdisciplinary field that integrates computer science with mathematics and statistics to solve biological questions. Many bioinformatic tools for gene prediction, homology modelling and such are available free online. State the functions of CLUSTAL W, BLAST and GLIDE (Schrödinger).
- List at least two ways in which computerized analysis oftranscriptomes aids genetic research.Describe the principle of a banding technique that can be used to helpvisualise chromosomes and chromosome regions during karyotyping.Summarize the basic steps in Differential Expression analysis starting with a directory of un-trimmed RNA-Seq reads and a genome. I’m looking for general descriptions of the steps, not code. Thank you!